Reaction of Local Anesthetics with Phospholipids

The Permeability of Natural Membranes

1944 • 752 citations

Effects of calcium ions and local anaesthetics on electrical properties of Purkinje fibres

1955 • 708 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. I. The resting cell and its alteration by extrinsic factors.

1958 • 579 citations

Effect of procaine on electrical properties of squid axon membrane

1959 • 285 citations

The effect of calcium on the myelinated nerve fibre

1957 • 252 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. II. The action potential and excitation.

1958 • 240 citations

On the Mechanism of the Relaxing Effect of Fragmented Sarcoplasmic Reticulum

1963 • 236 citations

New Measurements of the Capacity and the Resistance of the Myelin Sheath and the Nodal Membrane of the Isolated Frog Nerve Fiber

1955 • 215 citations

Aqueous Dispersions of Phosphatidylserine

1964 • 186 citations

ELECTROKINETIC MEMBRANE PROCESSES IN RELATION TO PROPERTIES OF EXCITABLE TISSUES

1959 • 182 citations

On the active structure of local anesthetics.

1961 • 168 citations

ANESTHETIC AND CALCIUM ACTION IN THE VOLTAGE CLAMPED SQUID GIANT AXON

1959 • 167 citations

Inhibition of Caffeine Rigor and Radiocalcium Movements by Local Anesthetics in Frog Sartorius Muscle

1963 • 152 citations

Phospholipid-Cholesterol Membrane Model

1962 • 125 citations

The Effect of Anesthetic Agents on Skeletal Muscle Membrane

1956 • 119 citations

ELECTROKINETIC MEMBRANE PROCESSES IN RELATION TO PROPERTIES OF EXCITABLE TISSUES

1959 • 102 citations

Experimentally altered structure related to function in the lobster axon with an extrapolation to molecular mechanisms in excitation

1958 • 85 citations

Isolation and identification of the acetylcholine receptor protein of electric tissue

1960 • 80 citations

Interactions of Veratrum Alkaloids, Procaine, and Calcium with Monolayers of Stearic Acid and Their Implications for Pharmacological Action

1960 • 71 citations

The action of calcium and of local anesthetics on nerve cells, and their interaction during excitation.

1963 • 68 citations

THE TITRATION OF SOME PHOSPHATIDES AND RELATED COMPOUNDS IN A NON-AQUEOUS MEDIUM

1956 • 68 citations

THE EFFECT OF CALCIUM IONS ON ELECTRICAL PROPERTIES OF STRIATED MUSCLE FIBRES

1957 • 68 citations

MECHANISM OF THE SELECTIVE FLUX OF SALTS AND IONS THROUGH NONAQUEOUS LIQUID MEMBRANES*

1961 • 65 citations

A PROPOSED COMMON MECHANISM OF ACTION FOR GENERAL AND LOCAL ANAESTHETICS IN THE CENTRAL NERVOUS SYSTEM

1963 • 63 citations

THE CATION CONTENT OF PHOSPHOLIPIDES FROM SWINE ERYTHROCYTES

1958 • 46 citations

Tissue lipids as ion exchangers for cations and the relationship to physiological processes

1962 • 43 citations

The active form of local anesthetics

1962 • 41 citations

The Role of Lipids

1958 • 39 citations

Acetylcholine and Nerve Activity

1964 • 34 citations

Basic Electrical Measurements

2005 • 34 citations

A study on the mechanism of action of cocaine on amphibian peripheral nerve.

1961 • 33 citations

THE HYDRATE MICROCRYSTAL THEORY OF GENERAL ANESTHESIA*

1964 • 22 citations

Role of the Cell Membrane and Mitochondria in the Phenomenon of Ion Transport in Cardiac Muscle

1954 • 16 citations

Physico-Chemical Experiments with Phosphatidyl Ethanolamine Sols

1963 • 13 citations

Depolarizing action of calcium-ion depletion on frog nerve and its inhibition by compounds acting on the acetylcholine system

1962 • 11 citations

[Effect of local anesthetics on ion-determined resting potential changes of myelinated nerve fibers in frogs].

1956 • 11 citations

The Influence of Amphoteric Surface Active Agents on the Diffusion and Carrier Transport of Salts and Ions Through Liquid Non-Aqueous Membranes

1962 • 11 citations

CONDUCTION BLOCK BY COCAINE IN SODIUM-DEPLETED NERVES WITH ACTIVITY MAINTAINED BY LITHIUM, HYDRAZINIUM OR GUANIDINIUM IONS.

1963 • 10 citations

Phosphatidylethanolamine and Lysophosphatidylethanolamine

1963 • 10 citations

Transfer of hydrophilic cations from an aqueous to a lipophilic phase by phosphatidic acids

1963 • 9 citations

THE EFFECTS OF CALCIUM IONS UPON THE SIZE OF THE ACTION CURRENT OF SINGLE MYELINATED NERVE FIBRES OF THE TOAD

1957 • 4 citations