Evidence for a reactive gamma-carboxyl group (Glu-418) at the herbicide glyphosate binding site of 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

An improved assay for nanomole amounts of inorganic phosphate

1979 • 2,157 citations

The herbicide glyphosate is a potent inhibitor of 5-enolpyruvylshikimic acid-3-phosphate synthase

1980 • 1,022 citations

A Method for the Quantitative Modification and Estimation of Carboxylic Acid Groups in Proteins

1967 • 927 citations

[36] High-sensitivity sequencing with a gas-phase sequenator

1983 • 670 citations

Adsorption, Mobility, and Microbial Degradation of Glyphosate in the Soil

1975 • 464 citations

Alkylation and Identification of the Histidine Residues at the Active Site of Ribonuclease

1963 • 423 citations

Expression in plants of a mutant aroA gene from Salmonella typhimurium confers tolerance to glyphosate

1985 • 370 citations

Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

1970 • 345 citations

Mode of action of N-phosphonomethylglycine. Inhibition of aromatic amino acid biosynthsis

1972 • 309 citations

Kinetics of 5‐enolpyruvylshikimate‐3‐phosphate synthase inhibition by glyphosate

1983 • 262 citations

A single amino acid substitution in the enzyme 5-enolpyruvylshikimate-3-phosphate synthase confers resistance to the herbicide glyphosate.

1985 • 232 citations

5‐Enolpyruvylshikimate‐3‐phosphate synthase of Klebsiella pneumoniae

1984 • 151 citations

The isolation and nucleotide sequence of the complexAROMlocus ofAspergillus nidulans

1986 • 133 citations

The shikimate pathway

1974 • 133 citations

Structure, expression, and evolution of the 5-enolpyruvylshikimate-3-phosphate synthase genes of petunia and tomato.

1988 • 128 citations

The Enzymatic Formation and Isolation of 3-Enolpyruvylshikimate 5-Phosphate

1964 • 108 citations

Evaluation of 5-enolpyruvoylshikimate-3-phosphate synthase substrate and inhibitor binding by stopped-flow and equilibrium fluorescence measurements

1988 • 103 citations

On the Mechanism of 5-Enolpyruvylshikimate 3-Phosphate Synthetase

1971 • 87 citations

Mechanism of enolpyruvylshikimate-3-phosphate synthase exchange of phosphoenolpyruvate with solvent protons

1983 • 72 citations

5‐Enolpyruvylshikimate‐3‐phosphate synthase of Klebsiella pneumoniae

1984 • 70 citations

The purification of 5‐enolpyruvylshikimate 3‐phosphate synthase from an overproducing strain of Escherichia coli

1984 • 68 citations

The complete amino acid sequence of Escherichia coli 5‐enolpyruvylshikimate 3‐phosphate synthase

1984 • 65 citations

Stable enzyme-phosphoenolpyruvate intermediate in the synthesis of uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-0-enolpyruvyl ether

1973 • 58 citations

Identification of the reactive cysteines of Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase and their nonessentiality for enzymatic catalysis.

1988 • 51 citations

Correlations between biological activity and the number of functional groups chemically modified

1979 • 47 citations

5-Enolpyruvyl shikimate 3-phosphate synthase from Escherichia coli. Identification of Lys-22 as a potential active site residue.

1988 • 39 citations

Mechanism of pyruvate-uridine diphospho-N-acetylglucosamine transferase. Evidence for an enzyme-enolpyruvate intermediate.

1975 • 36 citations

The fate of the hydrogens of phosphoenolpyruvate in the reaction catalyzed by 5-enolpyruvylshikimate-3-phosphate synthase. Isotope effects and isotope exchange.

1982 • 34 citations

Reaction of 5-enol-pyruvoylshikimate-3-phosphate synthase with diethyl pyrocarbonate: Evidence for an essential histidine residue

1987 • 17 citations

Proton magnetic resonance studies of DES‐(121–124)‐ribonuclease A

1973 • 16 citations