Correlations between biological activity and the number of functional groups chemically modified

Chemical Approaches to the Properties of Active Sites of Enzymes

1969 • 236 citations

A Method for Characterizing the Type and Numbers of Groups Involved in Enzyme Action

1961 • 236 citations

Relation between modification of functional groups of proteins and their biological activity. I.A graphical method for the determination of the number and type of essential groups.

1962 • 64 citations

Chemical modification of the arginines in transferrins

1978 • 62 citations

The Number of Catalytically Essential Carboxyl Groups in Pepsin

1972 • 59 citations

Modification of lactate oxidase with diethyl pyrocarbonate. Evidence for an active-site histidine residue

1977 • 43 citations

Essential Histidyl Residues in Arginine Oxygenase (Decarboxylating). Comparison with Amino Acid Oxidases

1971 • 39 citations

Effect of arginine modification on the catalytic activity and allosteric activation by adenosine diphosphate of the diphosphopyridine nucleotide specific isocitrate dehydrogenase of pig heart

1978 • 33 citations

Essential arginyl residues in yeast enolase

1978 • 32 citations

Inactivation of purine nucleoside phosphorylase by modification of arginine residues

1978 • 14 citations