Patterns of DNA methylation in selected human genes in different Hodgkin's lymphoma and leukemia cell lines and in normal human lymphocytes.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Genomic sequencing.

1984 • 8,343 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

1983 • 2,392 citations

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1977 • 2,134 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1983 • 1,407 citations

Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

1965 • 1,213 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium

1952 • 1,001 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

1986 • 711 citations

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

1985 • 652 citations

Human Lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization

1985 • 509 citations

Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses.

1982 • 309 citations

Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression.

1980 • 309 citations

Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line.

1983 • 290 citations

HL-60 cell line was derived from a patient with FAB-M2 and not FAB-M3

1988 • 233 citations

5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result

1979 • 182 citations

Patterns of integration of viral dna sequences in the genomes of adenovirus type 12-transformed hamster cells

1978 • 177 citations

Hodgkin's disease: Establishment and characterization of four in vitro cell lines

1981 • 162 citations

Two neoplastic cell lines with unique features derived from Hodgkin's disease

1980 • 159 citations

DNA methylation in adenovirus, adenovirus-transformed cells, and host cells.

1976 • 155 citations

Characteristics of Hodgkin's disease-derived cell lines.

1982 • 153 citations

Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.

1985 • 152 citations

Tandem Arrangement of Genes Coding for Tumor Necrosis Factor (TNF- ) and Lymphotoxin (TNF- ) in the Human Genome

1986 • 133 citations

Homologous cell-derived oncogenes in avian carcinoma virus MH2 and murine sarcoma virus 3611

1984 • 121 citations

Integration Sites of Adenovirus Type 12 DNA in Transformed Hamster Cells and Hamster Tumor Cells

1980 • 118 citations

Genomic sequencing reveals a 5-methylcytosine-free domain in active promoters and the spreading of preimposed methylation patterns.

1989 • 109 citations

Interleukin-2 Dependent Culture of Cytolytic T Cell Lines

1981 • 102 citations

Structural organization and expression of human DNA sequences related to the transforming gene of avian myeloblastosis virus.

1983 • 83 citations

Cell cycle dependency of a T-cell marker on lymphoblasts

1975 • 82 citations

Interindividual concordance of methylation profiles in human genes for tumor necrosis factors alpha and beta.

1990 • 67 citations

Eukaryotic DNA methylation: facts and problems

1990 • 63 citations

Shifts in the extent and patterns of DNA methylation upon explantation and subcultivation of adenovirus type 12-induced hamster tumor cells

1982 • 60 citations

Methylation of Integrated Viral DNA Sequences in Hamster Cells Transformed by Adenovirus 12

1980 • 54 citations

A Laboratory Guide to Genomic Sequencing

1987 • 46 citations

In vitro expression of human p53 cDNA clones and characterization of the cloned human p53 gene.

1985 • 38 citations

Morphologic, immunologic, enzymehistochemical and chromosomal analysis of a cell line derived from Hodgkin's disease

1985 • 30 citations

Complexities in Gene Regulation by Promoter Methylation

1989 • 25 citations

The significance of DNA methylation patterns: promoter inhibition by sequence-specific methylation is one functional consequence

1990 • 24 citations

Translocation t(8;22) in peripheral lymphocytes and established lymphoid cell lines from a patient with Hodgkin's disease followed by acute lymphatic leukemia

1982 • 20 citations

Molecular analysis of Hodgkin's disease‐derived cell lines

1988 • 15 citations