The product of the UTH1 gene, required for Bax‐induced cell death in yeast, is involved in the response to rapamycin
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References (51)
Autophagy as a Regulated Pathway of Cellular Degradation
2000 • 3,453 citations
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1999 • 3,194 citations
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast
1991 • 1,937 citations
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy
1998 • 1,381 citations
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction.
1992 • 1,187 citations
Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells
2000 • 1,125 citations
Oxygen Stress: A Regulator of Apoptosis in Yeast
1999 • 1,012 citations
The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
1999 • 918 citations
Mitochondria and apoptosis
1998 • 892 citations
A Caspase-Related Protease Regulates Apoptosis in Yeast
2002 • 868 citations
Mitochondrial permeability transition is a central coordinating event of apoptosis.
1996 • 857 citations
A Yeast Mutant Showing Diagnostic Markers of Early and Late Apoptosis
1997 • 788 citations
The autophagosomal–lysosomal compartment in programmed cell death
2001 • 599 citations
The Tumor Suppressor PTEN Positively Regulates Macroautophagy by Inhibiting the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway
2001 • 561 citations
Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae
1995 • 496 citations
Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution
1999 • 424 citations
Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis
2001 • 414 citations
CytochromecRelease and Mitochondria Involvement in Programmed Cell Death Induced by Acetic Acid inSaccharomyces cerevisiae
2002 • 368 citations
14-3-3 Proteins Mediate an Essential Anti-apoptotic Signal
2001 • 305 citations
Celecoxib Induces Apoptosis by Inhibiting 3-Phosphoinositide-dependent Protein Kinase-1 Activity in the Human Colon Cancer HT-29 Cell Line
2002 • 297 citations
Release of cytochrome c and decrease of cytochrome c oxidase in Bax‐expressing yeast cells, and prevention of these effects by coexpression of Bcl‐xL
1997 • 288 citations
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast
2001 • 271 citations
Growth Factors Inactivate the Cell Death Promoter BAD by Phosphorylation of Its BH3 Domain on Ser155
2000 • 225 citations
On the evolution of programmed cell death: apoptosis of the unicellular eukaryote Leishmania major involves cysteine proteinase activation and mitochondrion permeabilization
2002 • 217 citations
Mammalian Bax triggers apoptotic changes in yeast
1998 • 195 citations
Role of mitochondria and C‐terminal membrane anchor of Bcl‐2 in Bax induced growth arrest and mortality in Saccharomyces cerevisiae
1996 • 178 citations
Autophagy in Yeast: Mechanistic Insights and Physiological Function
2001 • 173 citations
A critical role for ethylene in hydrogen peroxide release during programmed cell death in tomato suspension cells
2002 • 155 citations
Escape of mitochondrial DNA to the nucleus in ymel yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments
1998 • 150 citations
Investigation of bax‐induced release of cytochrome c from yeast mitochondria
1999 • 131 citations
Aging and oxidative stress: studies of some genes involved both in aging and in response to oxidative stress
2001 • 107 citations
Functional Conservation of 14-3-3 Isoforms in Inhibiting Bad-Induced Apoptosis
2001 • 106 citations
Structural and functional analyses of APG5 a gene involved in autophagy in yeast
1996 • 103 citations
Apg5p Functions in the Sequestration Step in the Cytoplasm-to-Vacuole Targeting and Macroautophagy Pathways
2000 • 86 citations
Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast
1998 • 74 citations
Comparison of the effects of bax‐expression in yeast under fermentative and respiratory conditions: investigation of the role of adenine nucleotides carrier and cytochrome c
1999 • 65 citations
[10] ATP synthase from Saccharomyces cerevisiae
1995 • 64 citations
The ?SUN? family: yeastSUN4/SCW3 is involved in cell septation
2000 • 64 citations
Review: To bud until death: The genetics of ageing in the yeast, Saccharomyces
1996 • 59 citations
Involvement of the Saccharomyces cerevisiae UTH1 gene in the oxidative-stress response
1998 • 59 citations
Bax‐induced cell death in yeast depends on mitochondrial lipid oxidation
2002 • 58 citations
A cytochrome c–GFP fusion is not released from mitochondria into the cytoplasm upon expression of Bax in yeast cells
2000 • 49 citations
Bax expression protects yeast plasma membrane against ethanol‐induced permeabilization
2002 • 48 citations
The “SUN” Family: UTH1, an Ageing Gene, Is Also Involved in the Regulation of Mitochondria Biogenesis in Saccharomyces cerevisiae
2000 • 47 citations
Mechanisms of mitochondrial DNA escape to the nucleus in the yeast Saccharomyces cerevisiae
1999 • 47 citations
Role of the C‐terminal domain of Bax and Bcl‐xL in their localization and function in yeast cells
1999 • 46 citations
The substitution of the C‐terminus of bax by that of bcl‐xL does not affect its subcellular localization but abrogates its pro‐apoptotic properties
2000 • 42 citations
Dual cell wall/mitochondria localization of the âSUNâ family proteins
2002 • 41 citations
An ARL1 mutation affected autophagic cell death in yeast, causing a defect in central vacuole formation
2002 • 40 citations
Mitochondrial AAA-Type Protease Yme1p Is Involved in Bax Effects on Cytochrome c Oxidase
2001 • 28 citations
The SUN family ofSaccharomyces cerevisiae: the double knock-out ofUTH1andSIM1promotes defects in nucleus migration and increased drug sensitivity
2000 • 22 citations