The catalytic role of Cys124 in the dual specificity phosphatase VHR.

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

[6] Statistical analysis of enzyme kinetic data

1979 • 2,002 citations

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

1993 • 1,531 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes

1991 • 973 citations

The cdc25 protein contains an intrinsic phosphatase activity

1991 • 595 citations

PROTEIN TYROSINE PHOSPHATASES

1993 • 532 citations

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

1991 • 509 citations

Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate.

1991 • 468 citations

A Tyr/Ser protein phosphatase encoded by vaccinia virus

1991 • 403 citations

1002 Protein Phosphatases?

1992 • 330 citations

Protein-tyrosine phosphatases: The other side of the coin

1989 • 308 citations

The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts.

1993 • 305 citations

A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila.

1989 • 303 citations

Active site labeling of the Yersinia protein tyrosine phosphatase: The determination of the pKa of the active site cysteine and the function of the conserved histidine 402

1993 • 276 citations

The cdc25 M-phase inducer: An unconventional protein phosphatase

1992 • 266 citations

MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.

1994 • 241 citations

cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.

1992 • 234 citations

The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase.

1993 • 203 citations

Substrate specificity of the protein tyrosine phosphatases.

1993 • 189 citations

Expression cloning of a human dual-specificity phosphatase.

1992 • 188 citations

Oncogenes and the molecular origins of cancer

1990 • 177 citations

Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr protein phosphatase

1993 • 170 citations

KAP: a dual specificity phosphatase that interactswith cyclin-dependent kinases.

1994 • 147 citations

Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase.

1991 • 132 citations

Isolation and structural elucidation of a novel phosphocysteine intermediate in the LAR protein tyrosine phosphatase enzymic pathway

1992 • 103 citations

A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation.

1992 • 92 citations

Active site labeling of a receptor-like protein tyrosine phosphatase.

1992 • 63 citations

Cysteamine S-Phosphoric Acid.

1960 • 52 citations

Acidic residues are involved in substrate recognition by two soluble protein tyrosine phosphatases, PTP-5 and rrbPTP-1

1993 • 43 citations