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1991 • 421 citations

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1990 • 273 citations

Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation.

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Therapeutic potential of ACAT inhibitors as lipid lowering and anti-atherosclerotic agents

1991 • 193 citations

Studies on the assembly of apo B-100-containing lipoproteins in HepG2 cells.

1988 • 186 citations

Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment.

1990 • 182 citations

The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells. ApoB 100 is cotranslationally integrated into lipoproteins.

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Cholesterol is required for secretion of very-low-density lipoprotein by rat liver

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Studies on the synthesis and intracellular transport of lipoprotein particles in rat liver.

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Oleic acid stimulation of apolipoprotein B secretion from HepG2 and Caco-2 cells occurs post-transcriptionally

1990 • 151 citations

In vivo evidence that the lipid-regulating activity of the ACAT inhibitor CI-976 in rats is due to inhibition of both intestinal and liver ACAT.

1993 • 146 citations

The effect of low density lipoproteins, cholesterol, and 25-hydroxycholesterol on apolipoprotein B gene expression in HepG2 cells.

1992 • 136 citations

Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells.

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Lipoprotein apolipoprotein synthesis by human hepatoma cells in culture

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Regulation of hepatic secretion of very low density lipoprotein by dietary cholesterol.

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Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes

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1990 • 96 citations

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Pathogenesis of carbohydrate-induced hypertriglyceridemia using HepG2 cells as a model system.

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Effects of acyl-CoA: Cholesterol O-acyltransferase inhibition on cholesterol absorption and plasma lipoprotein composition in hamsters

1991 • 34 citations

Secretion of VLDL, but not HDL, by rat hepatocytes is inhibited by the ethanolamine analogue N-monomethylethanolamine.

1991 • 32 citations

Effect of simvastatin on the synthesis and secretion of lipoproteins in relation to the metabolism of cholesterol in cultured hepatocytes

1991 • 31 citations

Effect of chylomicron remnants on cholesterol metabolism in cultured rabbit hepatocytes: Very low density lipoprotein and bile acid production

1991 • 14 citations

VLDL apoprotein secretion and apo‐B mRNA level in primary culture of cholesterol‐loaded rabbit hepatocytes

1988 • 11 citations