Back to search

Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells

Data up to Jan 2025

Published2003
Citations82
References34

Total Citations Per Year

Abstract

References (34)

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

1965 • 1,338 citations

Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat

1990 • 650 citations

β-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial

2001 • 513 citations

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases.

1985 • 387 citations

Factors Associated with Early Remission of Type I Diabetes in Children Treated with Cyclosporine

1988 • 330 citations

Development of Type 1 Diabetes despite Severe Hereditary B-Cell Deficiency

2001 • 251 citations

Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation

1993 • 211 citations

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

2001 • 210 citations

Detection of GAD65-Specific T-Cells by Major Histocompatibility Complex Class II Tetramers in Type 1 Diabetic Patients and At-Risk Subjects

2002 • 198 citations

Redirection of Human Autoreactive T-Cells Upon Interaction With Dendritic Cells Modulated by TX527, an Analog of 1,25 Dihydroxyvitamin D3

2002 • 198 citations

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

2002 • 175 citations

Single-Cytokine-Producing CD4 Memory Cells Predominate in Type 1 and Type 2 Immunity

2000 • 174 citations

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

2002 • 148 citations

Autoreactive T cell Responses in Insulin-dependent (Type 1) Diabetes Mellitus. Report of the First International Workshop for Standardization of T cell assays

1999 • 130 citations

A T Cell Clone’s Avidity Is a Function of Its Activation State

2001 • 112 citations

ELISPOT Assay to Detect Cytokine‐Secreting Murine and Human Cells

2008 • 100 citations

Decreased Secretion of Th2 Cytokines Precedes Up-regulated and Delayed Secretion of Th1 Cytokines in Activated Peripheral Blood Mononuclear Cells from Patients with Insulin-Dependent Diabetes Mellitus

1998 • 80 citations

Characterization of Preparations of GAD65, Proinsulin, and the Islet Tyrosine Phosphatase IA-2 for Use in Detection of Autoreactive T-Cells in Type 1 Diabetes

2001 • 79 citations

Th1-like dominance in high-risk first-degree relatives of Type I diabetic patients

2000 • 78 citations

Application of the IFN-γ ELISPOT assay to quantify T cell responses against proteins

2001 • 74 citations

Increased Numbers ofin vivoActivated T cells in Patients with Recent Onset Insulin-dependent Diabetes Mellitus

1996 • 53 citations

A comparison between ELISPOT methods for the detection of cytokine producing cells: greater sensitivity and specificity using ELISA plates as compared to nitrocellulose membranes

1997 • 48 citations

Cytokine detection by ELISPOT: relevance for immunological studies in type 1 diabetes

2002 • 46 citations

Increase in Simultaneous Coexpression of Naive and Memory Lymphocyte Markers at Diagnosis of IDDM

1993 • 45 citations

<scp>ELISPOT</scp> Assay to Detect Cytokine‐Secreting Murine and Human Cells

1994 • 40 citations

DecreasedIn Vitroand IL-10 Production by Peripheral Blood in First Degree Relatives at High Risk of Diabetes Type-I

1998 • 31 citations

Detection of GAD65-Reactive T-Cells in Type 1 Diabetes by Immunoglobulin-Free ELISPOT Assays

2002 • 27 citations

Autoreactive T cells in endocrine/organ-specific autoimmunity: why has progress been so slow?

2002 • 22 citations

Increased CD69 and Human Leukocyte Antigen-DR Expression on T Lymphocytes in Insulin-Dependent Diabetes Mellitus of Long Standing

1998 • 19 citations

Increase in simultaneous coexpression of naive and memory lymphocyte markers at diagnosis of IDDM

1993 • 14 citations

Induction of Interferon-γ and IL-4 Production by Mitogen and Specific Antigens in Peripheral Blood Lymphocytes of Type 1 Diabetes Patients

2001 • 13 citations

Activated CD4+ and CD8+ T‐lymphocytes in Newly Diagnosed Type 1 Diabetes: a Prospective Study

1990 • 12 citations

Immunological studies on type 1 diabetes in identical twins.

1993 • 8 citations

Increased CD69 and Human Leukocyte Antigen-DR Expression on T Lymphocytes in Insulin-Dependent Diabetes Mellitus of Long Standing

1998 • 7 citations

Cited By (0)

No citing papers found in database

Comparison of cytokine ELISpot assay formats for the detection of islet antigen… (2003) – Journal of Autoimmunity | Metascience Observatory Explorer