Retinal glutamate transporter changes in experimental glaucoma and after optic nerve transection in the rat.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral Sclerosis

1992 • 1,170 citations

Optic Nerve Damage in Human Glaucoma

1982 • 1,167 citations

The Toxic Effect of Sodium L-Glutamate on the Inner Layers of the Retina

1957 • 1,061 citations

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.

1995 • 922 citations

Elevated Glutamate Levels in the Vitreous Body of Humans and Monkeys With Glaucoma

1996 • 646 citations

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

1990 • 630 citations

A Rat Model of Chronic Pressure-induced Optic Nerve Damage

1997 • 511 citations

Neuronal Regulation of Glutamate Transporter Subtype Expression in Astrocytes

1997 • 497 citations

Glutamate Transporters in Neurologic Disease

2001 • 324 citations

Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats.

2002 • 310 citations

Chronic low-dose glutamate is toxic to retinal ganglion cells. Toxicity blocked by memantine.

1996 • 283 citations

N-methyl-D-aspartate (NMDA)--induced apoptosis in rat retina.

1999 • 268 citations

Differential expression of three glutamate transporter subtypes in the rat retina

1996 • 245 citations

Functions of the two glutamate transporters GLAST and GLT-1 in the retina

1998 • 240 citations

Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex

1996 • 237 citations

Swelling and Loss of Photoreceptors in Chronic Human and Experimental Glaucomas

2000 • 201 citations

High-affinity glutamate transporters in the rat retina: a major role of the glial glutamate transporter GLAST-1 in transmitter clearance

1997 • 198 citations

Heterogeneity in localization of isoforms of TGF-beta in human retina, vitreous, and choroid.

1993 • 180 citations

Vitreous body glutamate concentration in dogs with glaucoma

1997 • 169 citations

Elevation of Intraocular Glutamate Levels in Rats With Partial Lesion of the Optic Nerve

1998 • 168 citations

Neurotoxic effects of low doses of glutamate on purified rat retinal ganglion cells.

1998 • 154 citations

Concurrent downregulation of a glutamate transporter and receptor in glaucoma.

2000 • 149 citations

Primary open-angle glaucoma is not associated with photoreceptor loss.

1995 • 147 citations

Depression of retinal glutamate transporter function leads to elevated intravitreal glutamate levels and ganglion cell death.

2000 • 141 citations

Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous d-aspartate

1993 • 138 citations

Optic nerve transection in monkeys may result in secondary degeneration of retinal ganglion cells.

2001 • 136 citations

Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia.

1998 • 130 citations

Localization of the glutamate transporter protein GLAST in rat retina

1997 • 129 citations

Müller cell protection of rat retinal ganglion cells from glutamate and nitric oxide neurotoxicity.

2000 • 121 citations

Efficacy and Safety of Memantine, an NMDA-Type Open-Channel Blocker, for Reduction of Retinal Injury Associated with Experimental Glaucoma in Rat and Monkey

2001 • 119 citations

Comparison of Ganglion Cell Loss and Cone Loss in Experimental Glaucoma

1995 • 102 citations

Glial glutamate transporter GLT-1 down-regulation precedes delayed neuronal death in gerbil hippocampus following transient global cerebral ischemia

2000 • 99 citations

Diversity of glutamate transporter expression and function in the mammalian retina

2000 • 90 citations

Retinal TUNEL-positive cells and high glutamate levels in vitreous humor of mutant quail with a glaucoma-like disorder.

1999 • 88 citations

Are neuronal transporters relevant in retinal glutamate homeostasis?

2000 • 67 citations

N -Methyl- D -Aspartate (NMDA) Induced Apoptosis in Adult Rabbit Retinas

2000 • 58 citations

Elevated Glutamate Levels in the Vitreous Body of an In Vivo Model of Optic Nerve Ischemia

2000 • 34 citations

Effect of glutamate transporter on neuronal damage induced by photochemical thrombotic brain ischemia

1998 • 20 citations