Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The determination of enzyme inhibitor constants

1953 • 4,050 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

A thousand and one protein kinases

1987 • 1,066 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells.

1990 • 336 citations

Protein kinases. Regulation by autoinhibitory domains.

1990 • 322 citations

Protein Phosphorylation Controls Translation Rates

1989 • 303 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases.

1988 • 282 citations

Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6.

1991 • 265 citations

Identification and characterization of a mitogen-activated S6 kinase.

1988 • 223 citations

Translation In Eukaryotes

1991 • 209 citations

MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

1991 • 208 citations

Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6.

1986 • 207 citations

A protein kinase from Xenopus eggs specific for ribosomal protein S6.

1985 • 195 citations

Molecular structure of a major insulin/mitogen-activated 70-kDa S6 protein kinase.

1990 • 194 citations

An activated S6 kinase in extracts from serum- and epidermal growth factor-stimulated Swiss 3T3 cells.

1984 • 193 citations

Identification of the 40 S ribosomal protein S6 phosphorylation sites induced by cycloheximide.

1988 • 184 citations

Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily.

1990 • 179 citations

Role of acidic residues as substrate determinants for casein kinase I

1991 • 158 citations

Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification.

1985 • 153 citations

Mitogen-activated 70K S6 kinase. Identification of in vitro 40 S ribosomal S6 phosphorylation sites.

1991 • 152 citations

Intrasteric regulation of protein kinases and phosphatases

1991 • 151 citations

Purification of a Hepatic S6 Kinase from Cycloheximide-treated Rats

1989 • 127 citations

Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif.

1990 • 125 citations

EGF induces biphasic S6 kinase activation: Late phase is protein kinase C-dependent and contributes to mitogenicity

1989 • 122 citations

S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment.

1988 • 118 citations

Ordered phosphorylation of 40S ribosomal protein S6 after serum stimulation of quiescent 3T3 cells.

1983 • 97 citations

The phosphorylation of eukaryotic ribosomal protein S6 by protein kinase C

1985 • 91 citations

Phosphorylation of hepatic ribosomal protein S6 on 80 and 40 S ribosomes. Primary structure of S6 in the region of the major phosphorylation sites for cAMP-dependent protein kinases.

1984 • 91 citations

A stimulated S6 kinase from rat liver: identity with the mitogen activated S6 kinase of 3T3 cells.

1989 • 82 citations

Magnetic resonance studies of the effect of the regulatory subunit on metal and substrate binding to the catalytic subunit of bovine heart protein kinase.

1980 • 82 citations

Purification and Characterization of a 40 S Ribosomal Protein S6 Kinase from Vanadate-stimulated Swiss 3T3 Cells

1989 • 76 citations

Unmasking a growth factor/oncogene-activated S6 phosphorylation cascade

1989 • 73 citations

Intracellular messengers and the control of protein synthesis

1991 • 60 citations

Reviews of Physiology, Biochemistry and Pharmacology, 119

1992 • 58 citations

Further definition of the substrate specificity of the alpha-herpesvirus protein kinase and comparison with protein kinases A and C

1991 • 52 citations

Relative stoichiometry in ribosomal proteins in HeLa cell nucleoli.

1976 • 39 citations

[34] Separation of multiple phosphorylated forms of 40 S ribosomal protein S6 by two-dimensional polyacrylamide gel electrophoresis

1987 • 37 citations

Purification and characterization of ribosomal protein S6 kinase I from Xenopus eggs.

1991 • 37 citations

Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase.

1990 • 30 citations

Determinants of multi-site phosphorylation of peptide analogues of ribosomal protein S6 by novel protease-activated protein kinases.

1991 • 9 citations