Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk.

Statistical Methods in Cancer Research

1980 • 6,825 citations

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

1977 • 1,196 citations

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1991 • 1,173 citations

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

1991 • 997 citations

Genetic Polymorphisms in the 5′-Flanking Region Change Transcriptional Regulation of the Human Cytochrome P450IIE1 Gene1

1991 • 671 citations

Relevance of nitrosamines to human cancer

1984 • 489 citations

Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene

1990 • 487 citations

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

1990 • 451 citations

Ethnic Differences in Alcohol Sensitivity

1972 • 373 citations

Isoenzyme(S) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow up study

1990 • 372 citations

Cytochrome P450IIe1: Roles in Nitrosamine Metabolism and Mechanisms of Regulation

1990 • 361 citations

Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes.

1982 • 269 citations

Association between Restriction Fragment Length Polymorphism of the Human Cytochrome P450IIE1 Gene and Susceptibility to Lung Cancer

1991 • 222 citations

Interindividual variation among humans in carcinogen metabolism, DNA adduct formation and DNA repair

1989 • 201 citations

Molecular Epidemiology and the Genetics of Environmental Cancer

1991 • 187 citations

The human glutathione S-transferases: a case-control study of the incidence of the GST1 0 phenotype in patients with adenocarcinoma

1991 • 176 citations

Lung Cancer and the Debrisoquine Metabolic Phenotype

1990 • 162 citations

cDNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment

1991 • 143 citations

Urinary excretion of N-nitrosamino acids and nitrate by inhabitants of high- and low-risk areas for esophageal cancer in Northern China: endogenous formation of nitrosoproline and its inhibition by vitamin C.

1986 • 136 citations

Pstl and Rsal RFLPs in complete linkage disequilibrium at the CYP2E gene

1990 • 97 citations

Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects

1988 • 90 citations

Radioimmunoassay of O⁶-methyldeoxyguanosine in DNA of cells alkylated in vitro and in vivo

1983 • 81 citations

Relevance of N-Nitroso Compounds to Human Cancer: Exposures and Mechanisms

1987 • 71 citations

Relevance of N-nitrosamines to esophageal cancer in China

1986 • 63 citations

Urinary excretion of N-nitrosamino acids and nitrate by inhabitants in high- and low-risk areas for stomach cancer in northern Japan.

1987 • 55 citations

Human debrisoquine hydroxylase gene polymorphisms in cancer patients and controls

1990 • 45 citations

Formation of dna adducts and water‐soluble metabolites of benzo[a]pyrene in human monocytes is genetically controlled

1988 • 40 citations

A correlation study on urinary excretion of N-nitroso compounds and cancer mortality in China: interim results.

1987 • 20 citations

Population studies of polymorphism in drug oxidation and its relevance to carcinogenesis.

1982 • 13 citations