Identification of a novel integrin beta subunit expressed on cultured monocytes (macrophages). Evidence that one alpha subunit can associate with multiple beta subunits.

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule.

1983 • 888 citations

Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin, fibrinogen, and von Willebrand factor.

1987 • 574 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.

1985 • 517 citations

Biologic properties in vitro of a recombinant human granulocyte- macrophage colony-stimulating factor

1986 • 458 citations

Induction of Macrophage Tumoricidal Activity by Granulocyte-Macrophage Colony-Stimulating Factor

1986 • 418 citations

Platelet Membrane Defects in Glanzmann's Thrombasthenia

1977 • 391 citations

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

1987 • 377 citations

Heterogeneous mutations in the β subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency

1987 • 373 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

Adhesive protein receptors on hematopoietic cells

1988 • 350 citations

The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the beta subunit.

1988 • 238 citations

Tenascin mediates cell attachment through an RGD-dependent receptor.

1989 • 231 citations

Regulatory properties of LFA-1 α and β chains in human T-lymphocyte activation

1988 • 225 citations

Orientation of cell-surface antigens in the lipid bilayer of lymphocyte plasma membrane

1977 • 175 citations

Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits.

1986 • 171 citations

Fibronectin receptors of phagocytes. Characterization of the Arg-Gly-Asp binding proteins of human monocytes and polymorphonuclear leukocytes.

1988 • 168 citations

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.

1986 • 152 citations

A murine antiglycoprotein Ib complex monoclonal antibody, SZ 2, inhibits platelet aggregation induced by both ristocetin and collagen

1987 • 146 citations

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits.

1987 • 131 citations

Isolation and Characterization of a Platelet Membrane Protein Related to the Vitronectin Receptor

1989 • 109 citations

The IIb-IIIa glycoprotein complex that mediates platelet aggregation is directly implicated in leukocyte adhesion

1986 • 83 citations

Monoclonal antibodies specific for platelet glycoproteins react with human monocytes

1984 • 71 citations

Synergism between membrane gangliosides and Arg-Gly-Asp-directed glycoprotein receptors in attachment to matrix proteins by melanoma cells.

1988 • 61 citations

Vitronectin (S protein) augments the functional activity of monocyte receptors for IgG and complement C3b

1988 • 49 citations

Monocytes and platelets share the glycoproteins IIb and IIIa that are absent from both cells in Glanzmann's thrombasthenia type I

1983 • 43 citations

In vitro growth of B lymphocytes infiltrating human melanoma tissue by transformation with EBV: evidence for secretion of anti-melanoma antibodies by some transformed cells.

1983 • 35 citations

Normal synthesis and expression of endothelial IIb/IIIa in Glanzmann's thrombasthenia

1987 • 29 citations

Characterization of calcium-dependent binding of endogenous factor VIII/von Willebrand factor to surface activated platelets

1984 • 22 citations