Posttranslational processing of human lysosomal acid beta-glucosidase: a continuum of defects in Gaucher disease type 1 and type 2 fibroblasts.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

1980 • 809 citations

Metabolism of glucocerebrosides II. Evidence of an enzymatic deficiency in Gaucher's disease

1965 • 800 citations

Nucleotide sequences of the mRNA's encoding the vesicular stomatitis virus G and M proteins determined from cDNA clones containing the complete coding regions

1981 • 404 citations

A Mutation in the Human Glucocerebrosidase Gene in Neuronopathic Gaucher's Disease

1987 • 343 citations

Molecular cloning and nucleotide sequence of human glucocerebrosidase cDNA.

1985 • 209 citations

Effect of microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane.

1984 • 209 citations

Genetic heterogeneity in type 1 Gaucher disease: multiple genotypes in Ashkenazic and non-Ashkenazic individuals.

1988 • 188 citations

Nucleotide sequences of the mRNA's encoding the vesicular stomatitis virus N and NS proteins

1981 • 169 citations

Protein synthesis in vesicular stomatitis virus-infected HeLa cells

1970 • 160 citations

Primary structure of the vesicular stomatitis virus polymerase (L) gene: evidence for a high frequency of mutations

1984 • 155 citations

Comparative Electrophoretic Analysis of the Virus Proteins of Four Rhabdoviruses

1974 • 144 citations

Biosynthesis of the lysosomal enzyme glucocerebrosidase.

1985 • 139 citations

Nucleotide sequence of cDNA containing the complete coding sequence for human lysosomal glucocerebrosidase.

1986 • 129 citations

Mutations of glucocerebrosidase: discrimination of neurologic and non-neurologic phenotypes of Gaucher disease.

1982 • 121 citations

Human acid beta-glucosidase. Use of conduritol B epoxide derivatives to investigate the catalytically active normal and Gaucher disease enzymes.

1986 • 65 citations

Genetic heterogeneity in Gaucher disease: Physicokinetic and immunologic studies of the residual enzyme in cultured fibroblasts from non‐neuronopathic and neuronopathic patients

1985 • 65 citations

Gaucher disease: genetic heterogeneity within and among the subtypes detected by immunoblotting.

1987 • 65 citations

Gaucher Disease Type 1: Cloning and Characterization of a cDNA Encoding Acid β-Glucosidase from an Ashkenazi Jewish Patient

1988 • 64 citations

Biosynthesis and maturation of arylsulfatase B in normal and mutant cultured human fibroblasts.

1983 • 62 citations

Cross-reacting material in Gaucher disease fibroblasts.

1984 • 47 citations

Pathology of the Gaucher cell.

1982 • 45 citations

Gaucher disease types 1, 2, and 3: differential mutations of the acid beta-glucosidase active site identified with conduritol B epoxide derivatives and sphingosine.

1985 • 43 citations

beta-Glucoside hydrolase activity of normal and glucosylceramidotic cultured human skin fibroblasts.

1977 • 40 citations

Glucocerebrosidase processing in normal fibroblasts and in fibroblasts from patients with type I, type II, and type III Gaucher disease.

1986 • 37 citations

Human acid beta-glucosidase: Northern blot and S1 nuclease analysis of mRNA from HeLa cells and normal and Gaucher disease fibroblasts.

1986 • 32 citations

Revision of the structure for an endo-beta-N-acetylglucosaminidase H substrate using a novel modification of the Smith degradation.

1981 • 29 citations

Complementation analysis in Gaucher disease using single cell microassay techniques. Evidence for a single ?Gaucher gene?

1983 • 26 citations

Immunological and catalytic quantitation of splenic glucocerebrosidase from the three clinical forms of Gaucher disease.

1983 • 25 citations

Comparison of Structural Polypeptides from Vesicular Stomatitis Virus (Indiana and New Jersey Serotypes) and Cocal Virus

1972 • 22 citations

Gaucher disease: a century of delineation and understanding.

1982 • 22 citations

Biochemical Studies in a Patient with Subacute Neuropathic Gaucher Disease without Visceral Glucosylceramide Storage

1983 • 20 citations