Estimating the power of a proposed linkage study for a complex genetic trait.

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

A General Model for the Genetic Analysis of Pedigree Data

1971 • 1,595 citations

Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

1974 • 1,022 citations

A genetic linkage map of the human genome

1987 • 913 citations

A comparison of sib‐pair linkage tests for disease susceptibility loci

1985 • 407 citations

Testing for heterogeneity of recombination fraction values in Human Genetics

1963 • 303 citations

Estimating the power of a proposed linkage study: a practical computer simulation approach.

1986 • 131 citations

The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity.

1983 • 124 citations

Genetic linkage between hereditary hemochromatosis and HLA.

1979 • 107 citations

Extensions to Pedigree Analysis

1983 • 87 citations

Detecting linkage for genetically heterogeneous diseases and detecting heterogeneity with linkage data.

1986 • 85 citations

Power of the affected‐sib‐pair method for heterogeneous disorders

1988 • 47 citations

Ancestral inference: I. The problem and the method

1978 • 19 citations

Sample-size considerations and strategies for linkage analysis in autosomal recessive disorders.

1986 • 13 citations

Sampling considerations in the design and analysis of family studies.

1984 • 11 citations

The impact of RFLPs on human gene mapping.

1984 • 9 citations