Back to search

Spillover and synaptic cross talk mediated by glutamate and GABA in the mammalian brain

Data up to Jan 2025

Published2000
Citations91
References63

Total Citations Per Year

Abstract

References (63)

Glutamate receptor ion channels

2005 • 3,667 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

GABAA Receptor Channels

1994 • 1,948 citations

Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice

1995 • 1,342 citations

Evidence for silent synapses: Implications for the expression of LTP

1995 • 1,212 citations

(–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

1980 • 1,091 citations

GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2

1998 • 1,054 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

Perisynaptic Location of Metabotropic Glutamate Receptors mGluR1 and mGluR5 on Dendrites and Dendritic Spines in the Rat Hippocampus

1996 • 845 citations

Three-Dimensional Relationships between Hippocampal Synapses and Astrocytes

1999 • 844 citations

Segregation of Different GABAAReceptors to Synaptic and Extrasynaptic Membranes of Cerebellar Granule Cells

1998 • 829 citations

Molecular Biology of Mammalian Plasma Membrane Amino Acid Transporters

1998 • 820 citations

Cell Type and Pathway Dependence of Synaptic AMPA Receptor Number and Variability in the Hippocampus

1998 • 798 citations

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors.

1996 • 724 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Local and diffuse synaptic actions of GABA in the hippocampus

1993 • 709 citations

Different modes of expression of AMPA and NMDA receptors in hippocampal synapses

1999 • 673 citations

The Number of Glutamate Transporter Subtype Molecules at Glutamatergic Synapses: Chemical and Stereological Quantification in Young Adult Rat Brain

1998 • 666 citations

GABAB autoreceptors regulate the induction of LTP

1991 • 613 citations

Intercellular communication in the brain: Wiring versus volume transmission

1995 • 555 citations

Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons

1997 • 551 citations

Synaptic Activation of Glutamate Transporters in Hippocampal Astrocytes

1997 • 511 citations

Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses

1999 • 496 citations

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors

1997 • 469 citations

Extrasynaptic Glutamate Diffusion in the Hippocampus: Ultrastructural Constraints, Uptake, and Receptor Activation

1998 • 437 citations

Extrasynaptic Glutamate Spillover in the Hippocampus: Dependence on Temperature and the Role of Active Glutamate Uptake

1997 • 425 citations

Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization

1994 • 420 citations

The synaptic activation of kainate receptors

1997 • 417 citations

Kinetics of a human glutamate transporter

1995 • 401 citations

Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1α, mGluR2 and mGluR5, relative to neurotransmitter release sites

1997 • 391 citations

Pre- and postsynaptic GABAB receptors in the hippocampus have different pharmacological properties

1988 • 368 citations

Frequency‐dependent depression of inhibition in guinea‐pig neocortex in vitro by GABAB receptor feed‐back on GABA release.

1989 • 348 citations

Spillover-Mediated Transmission at Inhibitory Synapses Promoted by High Affinity α6 Subunit GABAA Receptors and Glomerular Geometry

1998 • 345 citations

Impairment of Hippocampal Mossy Fiber LTD in Mice Lacking mGluR2

1996 • 342 citations

Clearance of glutamate inside the synapse and beyond

1999 • 329 citations

Extrasynaptic glutamate spillover in the hippocampus: evidence and implications

1998 • 324 citations

Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated

1999 • 321 citations

GABAB‐receptor splice variants GB1a and GB1b in rat brain: developmental regulation, cellular distribution and extrasynaptic localization

1999 • 303 citations

High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus

1995 • 292 citations

LTP of AMPA and NMDA Receptor–Mediated Signals: Evidence for Presynaptic Expression and Extrasynaptic Glutamate Spill-Over

1996 • 291 citations

Amplitude fluctuations of

1994 • 288 citations

Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.

1996 • 285 citations

Development of Action Potential‐dependent and Independent Spontaneous GABAA Receptor‐mediated Currents in Granule Cells of Postnatal Rat Cerebellum

1997 • 277 citations

Basal expression and induction of glutamate decarboxylase GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus

1996 • 244 citations

Glutamate Spillover Mediates Excitatory Transmission in the Rat Olfactory Bulb

1999 • 226 citations

Functional kainate-selective glutamate receptors in cultured hippocampal neurons.

1993 • 224 citations

Activation of AMPA, Kainate, and Metabotropic Receptors at Hippocampal Mossy Fiber Synapses

1998 • 200 citations

Three-dimensional analysis of dendritic spines

1985 • 184 citations

Glutamate and γ-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus

1999 • 182 citations

Geometric and viscous components of the tortuosity of the extracellular space in the brain

1998 • 178 citations

Baclofen selectively inhibits excitatory synaptic transmission in the hippocampus

1981 • 161 citations

Mechanism and Kinetics of Heterosynaptic Depression at a Cerebellar Synapse

1997 • 145 citations

The alpha 6 subunit of the GABAA receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells

1996 • 139 citations

Hippocampal synapses: do they talk to their neighbours?

1999 • 123 citations

G protein activation kinetics and spillover of gamma-aminobutyric acid may account for differences between inhibitory responses in the hippocampus and thalamus.

1995 • 115 citations

Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the α6 subunit gene

1999 • 112 citations

N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons.

1993 • 93 citations

Kainate Reveals Its Targets

1997 • 85 citations

Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-d-aspartate receptors in the rat hippocampus

1999 • 80 citations

Reduction by baclofen of monosynaptic EPSPs in lumbosacral motoneurones of the anaesthetized cat.

1989 • 75 citations

Synaptic coexistence of AMPA and NMDA receptors in the rat hippocampus: A postembedding immunogold study

1998 • 65 citations

Chapter 8 Synaptic arrangement of glutamate receptors

1998 • 24 citations

Cited By (0)

Loading...
Spillover and synaptic cross talk mediated by glutamate and GABA in the mammalian brain (2000) – Progress in brain research | Metascience Observatory Explorer