Factor IX New London: substitution of proline for glutamine at position 50 causes severe hemophilia B

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity

1981 • 4,191 citations

Prediction of protein conformation

1974 • 3,327 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Complete nucleotide sequences of the gene for human factor IX (antihemophilic factor B)

1985 • 683 citations

The nucleotide sequence of the gene for human protein C.

1985 • 360 citations

The solution structure of human epidermal growth factor

1987 • 322 citations

Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation.

1987 • 308 citations

[60] Computer analysis of nucleic acids and proteins

1980 • 238 citations

Gene deletions in patients with haemophilia B and anti-factor IX antibodies

1983 • 207 citations

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C

1986 • 204 citations

Proteolytic formation and properties of gamma-carboxyglutamic acid-domainless protein C.

1983 • 202 citations

Molecular pathology of haemophilia B.

1989 • 178 citations

Defective propeptide processing of blood clotting factor IX caused by mutation of arginine to glutamine at position −4

1986 • 176 citations

Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins.

1979 • 147 citations

Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor.

1986 • 129 citations

Calcium binding to the isolated β-hydroxyaspartic acid-containing epidermal growth factor-like domain of bovine factor X

1989 • 109 citations

Derivatives of blood coagulation factor IX contain a high affinity Ca2+-binding site that lacks gamma-carboxyglutamic acid.

1984 • 101 citations

Calcium-binding properties of bovine factor X lacking the gamma-carboxyglutamic acid-containing region.

1984 • 96 citations

Identification of the molecular defect in factor IX Chapel Hill: substitution of histidine for arginine at position 145.

1983 • 93 citations

Evidence for a prevalent dimorphism in the activation peptide of human coagulation factor IX.

1985 • 85 citations

Haemophilia B caused by a point mutation in a donor splice junction of the human factor IX gene

1985 • 84 citations

Molecular cloning of a cDNA encoding canine factor IX

1989 • 80 citations

Factor IXAlabama: a point mutation in a clotting protein results in hemophilia B

1987 • 60 citations

Two novel point mutations correlate with an altered developmental expression of blood coagulation factor IX (hemophilia B Leyden phenotype)

1989 • 55 citations

An intragenic deletion of the factor IX gene in a family with hemophilia B.

1985 • 47 citations

Monoclonal antibodies to factor IX: Characterization and use in immunoassays for factor IX

1984 • 40 citations

Characterization of the defect in activation of factor IX Chapel Hill by human factor XIa.

1981 • 39 citations

Hemophilia B Durham: a mutation in the first EGF-like domain of factor IX that is characterized by polymerase chain reaction

1988 • 37 citations

Hemophilia B with inhibitor: molecular analysis of the subtotal deletion of the factor IX gene

1985 • 30 citations

A de novo intragenic deletion of the potential EGF domain of the factor IX gene in a family with severe hemophilia B

1986 • 27 citations

Gene deletion in an Italian haemophilia B subject.

1985 • 24 citations

Defective propeptide processing and abnormal activation underlie the molecular pathology of factor IX Troed‐y‐Rhiw

1989 • 18 citations

A complete deletion of the factor IX gene and new TaqI variant in a hemophilia B kindred

1988 • 6 citations