FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1988 • 2,754 citations

Gases as biological messengers: nitric oxide and carbon monoxide in the brain

1994 • 1,052 citations

Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson disease

1997 • 676 citations

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

1995 • 632 citations

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.

1996 • 626 citations

Nitric oxide synthase and neuronal vulnerability in parkinson's disease

1996 • 588 citations

Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease

1994 • 576 citations

Protein Nitration in Parkinsonʼs Disease

1998 • 551 citations

Oxidative mechanisms in nigral cell death in Parkinson's disease.

1998 • 517 citations

Inhibition of neuronal nitric oxide synthase prevents MPTP–induced parkinsonism in baboons

1996 • 422 citations

Nitric oxide mediates iron release from ferritin

1990 • 290 citations

Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism

1996 • 271 citations

The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.

1995 • 270 citations

Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts.

1995 • 226 citations

Induction of Fc epsilon R2/CD23 on human epidermal Langerhans cells by human recombinant interleukin 4 and gamma interferon.

1989 • 209 citations

Expression, Structure, and Function of the CD23 Antigen

1991 • 207 citations

Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival.

1994 • 193 citations

Nitric oxide production by human monocytes: evidence for a role of CD23

1995 • 192 citations

A B cell-specific differentiation antigen, CD23, is a receptor for IgE (Fc epsilon R) on lymphocytes.

1987 • 183 citations

Ropinirole in the treatment of early Parkinson's disease: A 6‐month interim report of a 5‐year levodopa‐controlled study

1998 • 181 citations

Cloning and expression of the cDNA coding for a human lymphocyte IgE receptor.

1987 • 177 citations

Production and characterization of a monoclonal antibody specific for the human lymphocyte low affinity receptor for IgE: CD 23 is a low affinity receptor for IgE.

1987 • 159 citations

Inducible Nitric-oxide Synthase and Nitric Oxide Production in Human Fetal Astrocytes and Microglia

1997 • 150 citations

Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma.

1988 • 139 citations

Increased cerebrospinal fluid concentration of nitrite in Parkinsonʼs disease

1995 • 136 citations

Iron metabolism and Parkinson's disease.

1998 • 125 citations

The low-affinity receptor for IgE (CD23) on B lymphocytes is spatially associated with HLA-DR antigens.

1988 • 111 citations

Does Oxidative Stress Participate in Nerve Cell Death in Parkinson’s Disease?

1993 • 104 citations

Interleukin-4 stimulates cGMP production by IFN-gamma-activated human monocytes. Involvement of the nitric oxide synthase pathway

1994 • 100 citations

Structural and Functional Impact of the Transgenic Expression of Cytokines in the CNS^a

1998 • 80 citations

MPP+Induced Substantia Nigra Degeneration Is Attenuated in nNOS Knockout Mice

1997 • 69 citations

Involvement of Fcε:RII/CD23 and L-argininedependent pathway in IgE-mediated stimulation of human monocyte functions

1994 • 68 citations

Detection and characterization of monoclonal antibodies specific to IgE receptors on human lymphocytes by flow cytometry.

1985 • 66 citations

Distribution of manganese-dependent superoxide dismutase in the human brain

1994 • 65 citations

Functional implication for the topographical relationship between MHC class II and the low‐affinity IgE receptor: occupancy of CD23 prevents B lymphocytes from stimulating allogeneic mixed lymphocyte responses

1990 • 58 citations

Differential distribution of the normal and mutated forms of huntingtin in the human brain

1997 • 52 citations

Cyclosporin A attenuates degeneration of dopaminergic neurons induced by 6-hydroxydopamine in the mouse brain

1996 • 48 citations

Nitric oxide synthesis in rat peritoneal macrophages is induced by IgE/DNP complexes and cyclic AMP analogues. Evidence in favor of a common signaling mechanism.

1995 • 45 citations

Ligation of CD23 activates soluble guanylate cyclase in human monocytes via an L-arginine–dependent mechanism

1995 • 44 citations

CD23-Mediated Nitric Oxide Synthase Pathway Induction in Human Keratinocytes Is Inhibited by Retinoic Acid Derivatives

1996 • 42 citations

Simultaneous detection of ferritin and HIV-1 in reactive microglia

1992 • 36 citations

Receptors for IgE

1993 • 35 citations

Involvement of FcϵRII/CD23 and L-Arginine Dependent Pathway in IgE-Mediated Activation of Human Eosinophils

1994 • 35 citations

IgE receptors on human lymphocytes I. Identification of the molecules binding to monoclonal anti‐Fcε receptor antibodies

1986 • 32 citations

Thalidomide reduces MPTP-induced decrease in striatal dopamine levels in mice

1997 • 29 citations

REGULATION BY ENDOGENOUS INTERLEUKIN-10 OF THE EXPRESSION OF NITRIC OXIDE SYNTHASE INDUCED AFTER LIGATION OF CD23 IN HUMAN MACROPHAGES

1998 • 24 citations