Demonstration by radiation inactivation that insulin alters the structure of the insulin receptor in rat liver membranes.

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

Isolation of an organ specific protein antigen from cell-surface membrane rat liver

1968 • 883 citations

Site-site interactions among insulin receptors. Characterization of the negative cooperativity.

1976 • 601 citations

Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons.

1979 • 422 citations

Size determination of enzymes by radiation inactivation

1979 • 316 citations

Insulin receptor: covalent labeling and identification of subunits.

1979 • 243 citations

Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

1978 • 223 citations

Photoaffinity labeling of insulin receptor of rat adiopocyte plasma membrane.

1978 • 216 citations

Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins.

1979 • 211 citations

Photoaffinity labeling of insulin receptor proteins of liver plasma membrane preparations

1980 • 195 citations

Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody.

1980 • 187 citations

The subunit structure of rat liver insulin receptor. Antibodies directed against the insulin-binding subunit.

1980 • 144 citations

Characterization of the insulin receptor in its membrane environment by radiation inactivation.

1980 • 131 citations

Photoreactive insulin analogues used to characterise the insulin receptor

1980 • 101 citations

Insulin receptor: Interaction with nonreceptor glycoprotein from liver cell membranes

1978 • 100 citations

Insulin-induced dissociation of its receptor into subunits: Possible molecular concomitant of negative cooperativity

1976 • 96 citations

Insulin binding to solubilized material from fat cell membranes: Evidence for two binding species

1978 • 75 citations

Hormone Binding Alters the Conformation of the Insulin Receptor

1980 • 70 citations

Autoantibodies Against the Insulin Receptor Recognize the Insulin Binding Subunits of an Oligomeric Receptor

1981 • 64 citations

Subunit structure of the insulin receptor of the human lymphocyte

1980 • 61 citations

Multiple Redox Forms of the Insulin Receptor in Native Liver Membranes

1980 • 58 citations

Effects of insulin on insulin-binding components extracted from rat fat cell membranes

1979 • 26 citations

The Binding and Degradation of Insulin by Rat Liver Membranes: Demonstration of Three Distinct Insulin-Binding Components in Detergent-Solubilized Material from Liver Plasma Membrane*

1980 • 21 citations

Characteristics of the solubilized insulin receptor of human placenta

1978 • 20 citations

Target Molecular Weight of Mitochondrial ATPase*

1969 • 10 citations