Genetic analysis of adenine metabolism in Leishmania donovani promastigotes. Evidence for diploidy at the adenine phosphoribosyltransferase locus.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Evidence for diploidy and mating in trypanosomes

1980 • 226 citations

A novel adenosine and ara‐a deaminase inhibitor, (R)‐3‐(2‐deoxy‐β‐D‐erythro‐pentofuranosyl)‐3,6,7,8‐tetrahydroimidazo[4,5 ‐d] [1,3]diazepin‐8‐ol

1974 • 226 citations

Purine metabolism in Leishmania donovani and Leishmania braziliensis

1978 • 204 citations

Isotopes incorporated in the Nucleic Acids of Trypanosoma mega

1956 • 196 citations

On the DNA content and ploidy of trypanosomes

1982 • 169 citations

High Efficiency Plating Method for Leishmania Promastigotes in Semidefined or Completely-Defined Medium

1983 • 147 citations

Incorporation of Radioactive Precursors into DNA and RNA of Plasmodium knowlesi in vitro

1970 • 134 citations

Purine phosphoribosyltransferases from Leishmania donovani.

1980 • 134 citations

Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells

1974 • 133 citations

Inherited Disorder of Purine Metabolism

1967 • 130 citations

Mutants of cultured chinese hamster cells deficient in adenine phosphoribosyl transferase

1974 • 128 citations

Purine and Pyrimidine Synthesis by the Avian Malaria Parasite, Plasmodium lophurae*

1968 • 112 citations

Pyrazolopyrimidine metabolism in the pathogenic trypanosomatidae

1983 • 107 citations

A re-examination of purine and pyrimidine synthesis in the three main forms of Trypanosoma cruzi

1979 • 91 citations

Evidence for distinct 5′- and 3′-nucleotidase activities in the surface membrane fraction of Leishmania donovani promastigotes

1983 • 88 citations

High-frequency nonrandom mutational event at the adenine phosphoribosyltransferase (aprt) locus of sib-selected CHO variants heterozygous foraprt

1982 • 87 citations

Purine metabolism in Trypanosoma cruzi

1981 • 83 citations

Nucleosidases from Leishmania donovani. Pyrimidine ribonucleosidase, purine ribonucleosidase, and a novel purine 2'-deoxyribonucleosidase.

1979 • 81 citations

Characterization of DNA from Trypanosoma brucei and related trypanosomes by restriction endonuclease digestion

1980 • 79 citations

Metabolism of pyrazolo(3,4-d)pyrimidines in Leishmania braziliensis and Leishmania donovani. Allopurinol, oxipurinol, and 4-aminopyrazolo(3,4-d)pyrimidine.

1979 • 78 citations

Purine and pyrimidine salvage pathways in Leishmania donovani

1982 • 59 citations

Genetic effects of N-methyl-N′-nitro-N-nitrosoguanidine and its homologs

1982 • 58 citations

Model involving gene inactivation in the generation of autosomal recessive mutants in mammalian cells in culture.

1982 • 45 citations

Characterization of a mutant Leishmania donovani deficient in adenosine kinase activity

1984 • 45 citations

Adenine aminohydrolase: occurrence and possible significance in trypanosomid flagellates.

1979 • 44 citations

Purine Metabolism in Trypanosomatids*

1979 • 35 citations

Purification of Adenine Phosphoribosyltransferase by Affinity Chromatography

1978 • 34 citations

Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes.

1983 • 34 citations

[8] High-performance liquid chromatographic analysis of adenosyl-sulfur compounds related to polyamine biosynthesis

1983 • 29 citations

Mutations causing deficiency of APRT in fibroblasts cultured from humans heterozygous for mutantAPRT alleles

1982 • 29 citations

Reconstitution of malate-aspartate and α-glycerophosphate shuttle activity in rat skeletal muscle mitochondria

1979 • 6 citations