Mechanism of mutation at the aprt locus in Chinese hamster ovary cells: analysis of heterozygotes and hemizygotes.

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

DNA methylation and the frequency of CpG in animal DNA

1980 • 1,146 citations

Crossed Immunoelectrophoresis

1973 • 445 citations

Isolation of transforming DNA: Cloning the hamster aprt gene

1980 • 226 citations

Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured chinese hamster ovary cells

1980 • 151 citations

High-frequency nonrandom mutational event at the adenine phosphoribosyltransferase (aprt) locus of sib-selected CHO variants heterozygous foraprt

1982 • 87 citations

High-frequency mutation at the adenine phosphoribosyltransferase locus in Chinese hamster ovary cells due to deletion of the gene.

1983 • 52 citations

Model involving gene inactivation in the generation of autosomal recessive mutants in mammalian cells in culture.

1982 • 45 citations

Alterations of Gene Structure in Ethyl Methane Sulfonate-Induced Mutants of Mammalian Cells

1982 • 41 citations

Alterations of Gene Structure in Ethyl Methane Sulfonate-Induced Mutants of Mammalian Cells

1982 • 17 citations

Genetic instability in Drosophila melanogaster: deletion induction by insertion sequences.

1982 • 13 citations

Model Involving Gene Inactivation in the Generation of Autosomal Recessive Mutants in Mammalian Cells in Culture

1982 • 10 citations