Differential Effect of Anti-B7-1 and Anti-M150 Antibodies in Restricting the Delivery of Costimulatory Signals from B Cells and Macrophages

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 • 1,271 citations

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.

1992 • 1,029 citations

Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells

1988 • 917 citations

Signals and signs for lymphocyte responses

1994 • 868 citations

IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

1993 • 862 citations

Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

1992 • 843 citations

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells.

1990 • 679 citations

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

1995 • 577 citations

IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.

1997 • 528 citations

New perspectives of C1328-137-mediated T cell costimulation

1995 • 526 citations

A novel receptor involved in T-cell activation

1995 • 487 citations

Inducible T cell antigen 4-1BB. Analysis of expression and function.

1993 • 416 citations

Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD4+ T lymphocytes.

1992 • 395 citations

Absence of B7-dependent responses in CD28-deficient mice

1994 • 386 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.

1994 • 367 citations

B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.

1994 • 367 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations.

1991 • 355 citations

The role of T-cell subsets and cytokines in the regulation of infection

1991 • 352 citations

Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway

1991 • 325 citations

Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.

1995 • 271 citations

CD40 preferentially costimulates activation of CD4+ T lymphocytes.

1994 • 255 citations

Heat-stable antigen is a costimulatory molecule for CD4 T cell growth.

1992 • 254 citations

Antigen-reactive T cell clones. I. Transcomplementing hybrid I-A-region gene products function effectively in antigen presentation.

1980 • 252 citations

The ups and downs of T cell costimulation

1994 • 240 citations

T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells.

1988 • 212 citations

B7, a B-cell-restricted antigen that identifies preactivated B cells.

1987 • 211 citations

Inhibition of B lymphocyte activation by interferon-gamma.

1987 • 164 citations

B cell-stimulatory factor 1 (BSF-1) promotes growth of helper T cell lines.

1986 • 154 citations

B7–2 (CD86) is essential for the development of IL-4-producing T cells

1996 • 150 citations

Induction of B cell costimulatory function by recombinant murine CD40 ligand

1994 • 148 citations

Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells.

1990 • 144 citations

Murine B7 antigen provides an efficient costimulatory signal for activation of murine T lymphocytes via the T-cell receptor/CD3 complex.

1992 • 138 citations

CD43 is a murine T cell costimulatory receptor that functions independently of CD28.

1995 • 137 citations

Co‐stimulation of murine CD4 T cell growth: cooperation between B7 and heat‐stable antigen

1992 • 135 citations

Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo.

1994 • 132 citations

Nature and evolution of the eclipsing millisecond binary pulsar PSR1957 + 20

1988 • 125 citations

B7/CD28-dependent and -independent induction of CD40 ligand expression.

1995 • 91 citations

Novel mAbs reveal potent co-stimulatory activity of murine CD27

1995 • 83 citations

Human T helper cell differentiation is regulated by the combined action of cytokines and accessory cell-dependent costimulatory signals.

1997 • 62 citations

Functional drug targeting to erythrocytes in vivo using antibody bearing liposomes as drug vehicles

1987 • 56 citations

Costimulatory requirements of murine Th1 clones. The role of accessory cell-derived signals in responses to anti-CD3 antibody.

1990 • 56 citations

Monocytes provide a novel costimulatory signal to T cells that is not mediated by the CD28/B7 interaction.

1994 • 32 citations

Costimulatory signals can selectively modulate cytokine production by subsets of CD4+ T cells.

1995 • 30 citations

T cell receptor stimulation, but not CD28 costimulation, is dependent on LFA‐1‐mediated events

1994 • 29 citations

Activated B cells express CD28/B7-independent costimulatory activity.

1996 • 26 citations

A 150‐kDa molecule of macrophage membrane stimulates interleukin‐2 and interferon‐γ production and proliferation of ovalbumin‐specific CD4⁺ T cells

1994 • 16 citations