Cell-free synthesis of deoxyhypusine. Separation of protein substrate and enzyme and identification of 1,3-diaminopropane as a product of spermidine cleavage.

Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs

1978 • 998 citations

Polyamines as physiological substrates for transglutaminases.

1980 • 310 citations

Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor.

1981 • 267 citations

High-pressure liquid chromatographic determination of putrescine, cadaverine, spermidine and spermine

1979 • 210 citations

Identification of the hypusine-containing protein hy+ as translation initiation factor eIF-4D.

1983 • 205 citations

The biosynthesis of protein-bound hypusine (N epsilon -(4-amino-2-hydroxybutyl)lysine). Lysine as the amino acid precursor and the intermediate role of deoxyhypusine (N epsilon -(4-aminobutyl)lysine).

1982 • 154 citations

Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization.

1986 • 122 citations

Hypusine formation in protein by a two-step process in cell lysates.

1987 • 80 citations

Post-translational modification of the protein-synthesis initiation factor eIF-4D by spermidine in rat hepatoma cells

1986 • 74 citations

New methods for rapid separation and detection of oligosaccharides from glycoproteins

1988 • 62 citations

The biosynthesis of hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine). Alignment of the butylamine segment and source of the secondary amino nitrogen.

1984 • 54 citations

[256] Chemical synthesis of N-Acetyl-1,4-diamiho-butane, N1-Acetylpermidine, and N8-Acetyl-spermidine

1971 • 50 citations

Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides.

1987 • 47 citations

Cellular proliferation and hypusine synthesis

1984 • 39 citations

NAD⁺ stimulated the spermidine‐dependent hypusine formation on the 18 kDa protein in cytosolic lysates derived from NB‐15 mouse neuroblastoma cells

1988 • 38 citations

Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.

1986 • 37 citations

[53] Polyamine oxidase (oat seedlings)

1983 • 27 citations

The identification of an eukaryotic initiation factor 4D precursor in spermidine-depleted Chinese hamster ovary cells.

1988 • 23 citations

[80] Chromatographic identification of hypusine[N1-(4-amino-2-hydroxybutyl)lysine] and deoxyhypusine [N1-(4-aminobutyl)lysine]

1983 • 15 citations

Biosynthetic labeling of hypusine in mammalian cells. Carbon-hydrogen bond fissions revealed by dual labeling.

1986 • 13 citations

[241] Spermidine dehydrogenase (Serratia marcescens)

1971 • 6 citations