Characterization of the promoter region of the porcine opn (osteopontin, secreted phosphoprotein 1) gene

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

1986 • 1,078 citations

Osteopontin--a possible anchor of osteoclasts to bone.

1990 • 816 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo

1989 • 672 citations

The Nature and Significance of Osteopontin

1989 • 561 citations

Isolation and characterization of two sialoproteins present only in bone calcified matrix

1985 • 557 citations

Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization

1988 • 519 citations

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

1990 • 467 citations

Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone.

1987 • 437 citations

THE PATHWAY OF EUKARYOTIC mRNA FORMATION

1983 • 429 citations

Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.

1986 • 427 citations

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins.

1988 • 381 citations

Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone.

1987 • 373 citations

RNA Processing and the Intervening Sequence Problem

1979 • 353 citations

Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.

1990 • 343 citations

Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection.

1989 • 319 citations

Tissue specificity and developmental expression of rat osteopontin

1987 • 317 citations

Contacts between hormone receptor and DNA double helix within a glucocorticoid regulatory element of mouse mammary tumor virus.

1984 • 247 citations

Expression of bone matrix proteins associated with mineralized tissue formation by adult rat bone marrow cells in vitro: Inductive effects of dexamethasone on the osteoblastic phenotype

1991 • 238 citations

Developmental expression of 44-kDa bone phosphoprotein (osteopontin) and bone γ-carboxyglutamic acid (Gla)-containing protein (osteocalcin) in calcifying tissues of rat

1988 • 218 citations

Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin

1989 • 194 citations

Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer

1990 • 193 citations

Immunohistochemical demonstration of a 44-KD phosphoprotein in developing rat bones.

1987 • 187 citations

Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation.

1988 • 187 citations

1,25-Dihydroxyvitamin D3 Regulates the Biosynthesis of Osteopontin, a Bone-Derived Cell Attachment Protein, in Clonal Osteoblast-Like Osteosarcoma Cells

1987 • 187 citations

[8] Purification and cryopreservation of phagocytes from human blood

1986 • 174 citations

The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone

1991 • 169 citations

The Z-DNA motif d(TG)30 promotes reception of information during gene conversion events while stimulating homologous recombination in human cells in culture.

1990 • 147 citations

The cDNA and derived amino acid sequence for human osteopontin

1989 • 147 citations

Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues

1990 • 143 citations

Characterization of fetal porcine bone sialoproteins, secreted phosphoprotein I (SPPI, osteopontin), bone sialoprotein, and a 23-kDa glycoprotein. Demonstration that the 23-kDa glycoprotein is derived from the carboxyl terminus of SPPI.

1990 • 128 citations

Two silencers regulate the tissue-specific expression of the collagen II gene.

1990 • 128 citations

The mouse osteopontin gene. Expression in monocytic lineages and complete nucleotide sequence.

1990 • 125 citations

Identification of the major phosphoprotein secreted by many rodent cell lines as 2AR/osteopontin: Enhanced expression in H-RAS-transformed 3T3 cells

1988 • 117 citations

44-kDal bone phosphoprotein (osteopontin) antigenicity at ectopic sites in newborn rats: kidney and nervous tissues

1988 • 116 citations

Normal rat kidney cells secrete both phosphorylated and nonphosphorylated forms of osteopontin showing different physiological properties

1989 • 104 citations

Multiple forms of SppI (secreted phosphoprotein, osteopontin) synthesized by normal and transformed rat bone cell populations: Regulation by TGF-β

1989 • 103 citations

Cell Attachment Activity of the 44 Kilodalton Bone Phosphoprotein is not Restricted to Bone Cells

1989 • 91 citations

Sulphation of secreted phosphoprotein I (SPPI, osteopontin) is associated with mineralized tissue formation

1989 • 91 citations

Differential regulation of the 55 and 44 kDa forms of secreted phosphoprotein 1 (SPP-1, osteopontin) in normal and transformed rat bone cells by osteotropic hormones, growth factors and a tumor promoter

1991 • 74 citations

Full length cDNA sequence of porcine secreted phosphoprotein-I (SPP-I, osteopontin)

1989 • 61 citations

Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance)

1989 • 59 citations

Characterization of the Promoter Region of the Human Thrombospondin Gene

1989 • 54 citations

Regulation of transformation-sensitive secreted phosphoprotein (SPPI/osteopontin) expression by transforming growth factor-β. Comparisons with expression of SPARC (secreted acidic cysteine-rich protein)

1991 • 50 citations

Evidence for Positive and Negative Regulatory Elements in the 5′-Flanking Sequence of the Mouse Sparc (osteonectin) Gene

1989 • 48 citations

Transcription and Splicing

1989 • 37 citations

Homologous recombination enhancement conferred by the Z-DNA motif d(TG)30 is abrogated by simian virus 40 T antigen binding to adjacent DNA sequences.

1990 • 27 citations

Identification of pre-osteonectin produced by cell-free translation of fetal porcine calvarial mRNA.

1985 • 22 citations