The Nature and Significance of Osteopontin

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

1986 • 1,078 citations

Isolation and characterization of two sialoproteins present only in bone calcified matrix

1985 • 557 citations

Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization

1988 • 519 citations

A Comparative Study of Human Periodontal Ligament Cells and Gingival Fibroblasts in vitro

1988 • 505 citations

Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone.

1987 • 437 citations

Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone.

1987 • 373 citations

Tissue specificity and developmental expression of rat osteopontin

1987 • 317 citations

Dentin phosphoprotein: an extracellular calcium-binding protein

1977 • 225 citations

Developmental expression of 44-kDa bone phosphoprotein (osteopontin) and bone γ-carboxyglutamic acid (Gla)-containing protein (osteocalcin) in calcifying tissues of rat

1988 • 218 citations

Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor.

1988 • 206 citations

1,25-Dihydroxyvitamin D3 Regulates the Biosynthesis of Osteopontin, a Bone-Derived Cell Attachment Protein, in Clonal Osteoblast-Like Osteosarcoma Cells

1987 • 187 citations

Immunohistochemical demonstration of a 44-KD phosphoprotein in developing rat bones.

1987 • 187 citations

Phosphophoryns—major noncollagenous proteins of rat incisor dentin

1978 • 160 citations

Molecular cloning of a tumor promoter‐inducible mRNA found in JB6 mouse epidermal cells: Induction is stable at high, but not at low, cell densities

1987 • 132 citations

Transcriptional regulation of osteopontin production in rat osteoblast-like cells by parathyroid hormone.

1989 • 130 citations

Mechanism of fibroblast attachment to bone extracellular matrix: Role of a 44 kilodalton bone phosphoprotein

1987 • 123 citations

Human bone sialoprotein I and II enhance fibroblast attachmentin vitro

1988 • 123 citations

Multiple forms of rat dentin phosphoproteins

1983 • 122 citations

Identification of the major phosphoprotein secreted by many rodent cell lines as 2AR/osteopontin: Enhanced expression in H-RAS-transformed 3T3 cells

1988 • 117 citations

44-kDal bone phosphoprotein (osteopontin) antigenicity at ectopic sites in newborn rats: kidney and nervous tissues

1988 • 116 citations

Calcium-specific Precipitation of Dentin Phosphoprotein: A New Method of Purification and the Significance for the Mechanism of Calcification

1979 • 110 citations

Bovine dentin phosphophoryn: composition and molecular weight

1983 • 110 citations

Production and characterization of antibodies against murine dentine phosphoprotein

1985 • 91 citations

Cell Attachment Activity of the 44 Kilodalton Bone Phosphoprotein is not Restricted to Bone Cells

1989 • 91 citations

A comparative immunocytochemical study on the subcellular distributions of 44 kDa bone phosphoprotein and bone γ-carboxyglutamic acid (Gla)-containing protein in osteoblasts

1987 • 88 citations

Identification of organic phosphorus covalently bound to collagen and non-collagenous proteins of chicken-bone matrix. The presence of O-phosphoserine and O-phosphothreonine in non-collagenous proteins, and their absence from phosphorylated collagen

1979 • 82 citations

Secreted phosphoprotein markers for neoplastic transformation of human epithelial and fibroblastic cells.

1985 • 71 citations

The extraction and characterization of soluble anionic phosphoproteins from bone

1972 • 69 citations

Purification, composition, and31P NMR spectroscopic properties of a noncollagenous phosphoprotein isolated from chicken bone matrix

1981 • 65 citations

The isolation of anionic phosphoproteins from bovine cortical bone Via the periodate solubilization of bone collagen

1972 • 61 citations

Noncollagenous proteins of rat compact bone.

1983 • 50 citations

Isolation and chemical characterization of the phosphoproteins of chicken bone matrix: heterogeneity in molecular weight and composition

1986 • 47 citations

The Role of Collagen and Phosphoproteins in the Calcification of Bone and Other Collagenous Tissues

1985 • 26 citations

Regulation of the attachment and migration of bone cells in vitro

1982 • 16 citations

Comparative Studies of Phosphoprotein Preparations from Rat Incisor Dentin

1980 • 13 citations