Transcriptional Responses to Growth Factor and G Protein‐Coupled Receptors in PC12 Cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

1994 • 3,249 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

The mitogen-activated protein kinase signal transduction pathway

1993 • 2,174 citations

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

1995 • 2,080 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

1996 • 1,946 citations

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

1991 • 1,300 citations

Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity

1995 • 1,287 citations

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1995 • 906 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.

1994 • 678 citations

Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor

1993 • 592 citations

The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

1998 • 582 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

Transcriptional regulation in the immune system: all roads lead to AP-1

1998 • 388 citations

α1-Adrenoceptor subtypes

1999 • 388 citations

Signaling routes to CREM and CREB: plasticity in transcriptional activation

1999 • 304 citations

Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).

1995 • 255 citations

Dynamic Complexes of β2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role of Gravin

1999 • 208 citations

Activation of P2Y2 Receptors by UTP and ATP Stimulates Mitogen-activated Kinase Activity through a Pathway That Involves Related Adhesion Focal Tyrosine Kinase and Protein Kinase C

1998 • 179 citations

Cloning, Functional Expression and Tissue Distribution of Human cDNA for the α1C-Adrenergic Receptor

1993 • 154 citations

Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: titration of receptor density and responsiveness with inducible and repressible expression vectors.

1996 • 122 citations

The Cyclosporin A-sensitive Nuclear Factor of Activated T Cells (NFAT) Proteins Are Expressed in Vascular Smooth Muscle Cells

1998 • 102 citations

Differential Coupling of α1-, α2-, and β-Adrenergic Receptors to Mitogen-activated Protein Kinase Pathways and Differentiation in Transfected PC12 Cells

1998 • 102 citations

Phosphorylation-Dependent Formation of a Quaternary Complex at the c-fos SRE

1996 • 62 citations

Differential Activation of Mitogen‐Activated Protein Kinase Pathways in PC12 Cells by Closely Related α₁‐Adrenergic Receptor Subtypes

1999 • 58 citations

Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells.

1995 • 51 citations

No Role for Ca⁺⁺or Protein Kinase C inAlpha-1A Adrenergic Receptor Activation of Mitogen-Activated Protein Kinase Pathways in Transfected PC12 Cells

1999 • 36 citations

G-Protein-Linked Receptors as Tyrosine Kinase Substrates

1998 • 30 citations

Differential Regulation of Vascular Smooth Muscle Nuclear Factor kappa-B by G α q-coupled and Cytokine Receptors

2000 • 28 citations

Activation of tyrosine kinases by α1A-adrenergic and growth factor receptors in transfected PC12 cells

1999 • 24 citations

Activation of tyrosine kinases by α1A-adrenergic and growth factor receptors in transfected PC12 cells

1999 • 7 citations