Transduction and adaptation in sensory receptor cells

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

1991 • 4,793 citations

Experiments in Hearing

1963 • 1,763 citations

A cyclic nucleotide-gated conductance in olfactory receptor cilia

1987 • 1,134 citations

ENERGY, QUANTA, AND VISION

1942 • 1,101 citations

Responses of retinal rods to single photons.

1979 • 971 citations

A fast motile response in guinea‐pig outer hair cells: the cellular basis of the cochlear amplifier.

1987 • 826 citations

Measurement of basilar membrane motion in the guinea pig using the Mössbauer technique

1982 • 753 citations

The active cochlea

1992 • 708 citations

Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction

1984 • 694 citations

The photocurrent, noise and spectral sensitivity of rods of the monkey Macaca fascicularis.

1984 • 689 citations

Amplification and kinetics of the activation steps in phototransduction

1993 • 645 citations

Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells

1990 • 639 citations

A quantitative account of the activation steps involved in phototransduction in amphibian photoreceptors.

1992 • 632 citations

Cyclic GMP-Activated Conductance of Retinal Photoreceptor Cells

1989 • 582 citations

Changes in time scale and sensitivity in turtle photoreceptors

1974 • 539 citations

Kinetics of the receptor current in bullfrog saccular hair cells

1983 • 539 citations

Visual excitation and recovery

1991 • 530 citations

The electrical response of turtle cones to flashes and steps of light

1974 • 471 citations

Two components of electrical dark noise in toad retinal rod outer segments.

1980 • 462 citations

Furosemide alters organ of corti mechanics: evidence for feedback of outer hair cells upon the basilar membrane

1991 • 434 citations

Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin

1993 • 401 citations

Modulation of the cGMP-gated channel of rod photoreceptor cells by calmodulin

1993 • 401 citations

Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment

1985 • 381 citations

Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration

1988 • 349 citations

Signal sorting and amplification through G protein-coupled receptors

1989 • 338 citations

Adaptation of mechanoelectrical transduction in hair cells of the bullfrog's sacculus

1987 • 337 citations

Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells

1993 • 315 citations

The actions of calcium on the mechano‐electrical transducer current of turtle hair cells.

1991 • 315 citations

Variation of membrane properties in hair cells isolated from the turtle cochlea.

1987 • 304 citations

High-Frequency Motility of Outer Hair Cells and the Cochlear Amplifier

1995 • 304 citations

Activation and adaptation of transducer currents in turtle hair cells.

1989 • 296 citations

Discrimination of molecular signals by the olfactory receptor neuron

1994 • 293 citations

The calcium feedback signal in the phototransduction cascade of vertebrate rods

1994 • 290 citations

Calcium-activated chloride conductance in frog olfactory cilia

1991 • 288 citations

An active motor model for adaptation by vertebrate hair cells

1992 • 253 citations

Response latency of vertebrate hair cells

1979 • 242 citations

Calcium-dependent regulation of cyclic GMP phosphodiesterase by a protein from frog retinal rods

1991 • 242 citations

A voltage‐clamp study of the light response in solitary rods of the tiger salamander.

1979 • 241 citations

The concentration of cytosolic free calcium in vertebrate rod outer segments measured with fura-2

1988 • 234 citations

The relation between stimulus and response in olfactory receptor cells of the tiger salamander.

1993 • 232 citations

The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium

1991 • 224 citations

Signaling pathways in odorant detection

1992 • 218 citations

The relation between intercellular coupling and electrical noise in turtle photoreceptors.

1976 • 218 citations

Response properties of cones from the retina of the tiger salamander.

1991 • 215 citations

The transduction channel of hair cells from the bull‐frog characterized by noise analysis.

1986 • 215 citations

Light response of vertebrate photoreceptors

1990 • 208 citations

Role of cGMP and Ca2+ in Vertebrate Photoreceptor Excitation and Adaptation

1992 • 198 citations

Odor-Induced Membrane Currents in Vertebrate-Olfactory Receptor Neurons

1989 • 191 citations

On the frequency limit and phase of outer hair cell motility: effects of the membrane filter

1992 • 190 citations

Cyclic Nucleotide-Gated Ion Channels and Sensory Transduction in Olfactory Receptor Neurons

1994 • 190 citations

Ca2+-dependent adaptive properties in the solitary olfactory receptor cell of the newt

1990 • 187 citations

Calcium homeostasis in the outer segments of retinal rods from the tiger salamander.

1992 • 186 citations

Reverse transduction measured in the isolated cochlea by laser Michelson interferometry

1993 • 185 citations

Two-tone distortion in the basilar membrane of the cochlea

1991 • 176 citations

Localization of the hair cell's transduction channels at the hair bundle's top by iontophoretic application of a channel blocker

1991 • 172 citations

Activation by odorants of cation‐selective conductance in the olfactory receptor cell isolated from the newt.

1989 • 165 citations

Purification and identification of photoreceptor guanylate cyclase

1991 • 162 citations

Light adaptation and photopigment bleaching in cone photoreceptors in situ in the retina of the turtle

1994 • 161 citations

Role of calcium in regulating the cyclic GMP cascade of phototransduction in retinal rods.

1986 • 160 citations

Calcium controls light-triggered formation of catalytically active rhodopsin

1994 • 153 citations

Localization of cholinergic and purinergic receptors on outer hair cells isolated from the guinea-pig cochlea

1992 • 142 citations

The involvement of rod photoreceptors in dark adaptation

1981 • 141 citations

Time course of the membrane current underlying sensory transduction in salamander olfactory receptor neurones.

1990 • 138 citations

Block by amiloride and its derivatives of mechano‐electrical transduction in outer hair cells of mouse cochlear cultures.

1994 • 135 citations

Kinetics of phototransduction in retinal rods of the newt Triturus cristatus.

1989 • 133 citations

A molecular dissection of spatial patterning in the olfactory system

1994 • 130 citations

Auditory illusions and the single hair cell

1993 • 122 citations

Calcium and the mechanism of light adaptation in vertebrate photoreceptors

1990 • 112 citations

Free calcium concentrations in bullfrog rods determined in the presence of multiple forms of Fura-2

1994 • 106 citations

Models for electrical tuning in hair cells

1985 • 92 citations

Dark adaptation of toad rod photoreceptors following small bleaches

1994 • 91 citations

Quantal-like current fluctuations induced by odorants in olfactory receptor cells

1995 • 89 citations

Analysis of electrical noise in turtle cones

1977 • 86 citations

The role of outer hair cell motility in cochlear tuning

1991 • 75 citations

High density cAMP-gated channels at the ciliary membrane in the olfactory receptor cell

1991 • 74 citations

Spontaneous quantal events induced in toad rods by pigment bleaching

1980 • 68 citations

Brownian Motion in the Cochlear Partition

1968 • 68 citations

Activation kinetics of retinal cones and rods: response to intense flashes of light

1990 • 64 citations

Incorporation of chelator into guinea‐pig rods shows that calcium mediates mammalian photoreceptor light adaptation.

1991 • 54 citations

Conductance and kinetics of single cGMP‐activated channels in salamander rod outer segments.

1995 • 52 citations

Hair cell based amplification in the cochlea

1994 • 52 citations

The cloning of a mechano-gated membrane ion channel

1994 • 43 citations

Cyclic nucleotide-gated channels in visual and olfactory transduction

1995 • 42 citations

Biophysical principles of sensory transduction.

1992 • 40 citations

Cyclic GMP‐activated channels of salamander retinal rods: spatial distribution and variation of responsiveness.

1992 • 36 citations

Cyclic GMP-Activated Conductance Of Retinal Photoreceptor Cells

1989 • 34 citations

Gating, selectivity and blockage of single channels activated by cyclic GMP in retinal rods of the tiger salamander.

1994 • 32 citations

The Ear's Gears: Mechanoelectrical Transduction by Hair Cells

1994 • 31 citations

The G.L. Brown Prize Lecture. The cellular machinery of the cochlea

1994 • 31 citations

Role Of cGMP And Ca2+ In Vertebrate Photoreceptor Excitation And Adaptation

1992 • 29 citations

Selectivity and Single-Channel Properties of the cGMP-Activated Channel in Amphibian Retinal Rods

1994 • 13 citations

Molecular Aspects of Photoreceptor Adaptation in Vertebrate Retina

1993 • 12 citations

Brownian Motion in the Cochlear Partition

1966 • 4 citations