Retargeting T Cell-Mediated Inflammation: A New Perspective on Autoantibody Action

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

1996 • 581 citations

REGULATION OF OVARIAN FOLLICLE ATRESIA

1997 • 448 citations

A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease.

1987 • 368 citations

Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease.

1995 • 367 citations

Experimental Allergic Encephalomyelitis. A Useful Model for Multiple Sclerosis

1984 • 340 citations

B Lymphocytes Producing Demyelinating Autoantibodies: Development and Function in Gene-targeted Transgenic Mice

1998 • 241 citations

The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat

1995 • 231 citations

I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice.

1999 • 228 citations

Vaccination with a Synthetic Zona Pellucida Peptide Produces Long-Term Contraception in Female Mice

1989 • 213 citations

Fc receptors

1997 • 198 citations

Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida.

1992 • 190 citations

I-Ag7-Mediated Antigen Presentation by B Lymphocytes Is Critical in Overcoming a Checkpoint in T Cell Tolerance to Islet β Cells of Nonobese Diabetic Mice

1999 • 190 citations

Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

1997 • 178 citations

Transgenic tumor necrosis factor (TNF)-alpha production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-alpha and TNF-beta transgenic mice.

1993 • 169 citations

Distribution of histopathology and Ia positive cells in actively induced and passively transferred experimental autoimmune orchitis.

1987 • 147 citations

Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody

1992 • 146 citations

Myelin Oligodendrocyte Glycoprotein Induces Experimental Autoimmune Encephalomyelitis in the “Resistant” Brown Norway Rat: Disease Susceptibility Is Determined by MHC and MHC-Linked Effects on the B Cell Response

1999 • 144 citations

Autoimmunity and Autoimmune Diseases

1989 • 137 citations

Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice

1991 • 129 citations

Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes. A gene therapy model for autoimmune diabetes.

1996 • 128 citations

A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology.

1995 • 124 citations

Interaction between myelin basic protein-sensitized T lymphocytes and murine cerebral vascular endothelial cells.

1986 • 117 citations

The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells.

1996 • 104 citations

Adoptive T cell transfer of autoimmune nonobese diabetic mouse diabetes does not require recruitment of host B lymphocytes.

1988 • 92 citations

Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis

1992 • 86 citations

Immunohistochemical Studies of the Adult Human Ovary: Possible Contribution of Immune and Epithelial Factors to Folliculogenesis

1995 • 80 citations

T cell peptide of a self-protein elicits autoantibody to the protein antigen. Implications for specificity and pathogenetic role of antibody in autoimmunity.

1993 • 73 citations

A modified method to induce immune polyclonal ascites fluid in BALB/c mice using Sp2/0-Ag14 cells

1986 • 66 citations

Major Histocompatibility Complex Class II Expression by Intrinsic Renal Cells Is Required for Crescentic Glomerulonephritis

1998 • 64 citations

A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha.

1989 • 60 citations

A Contraceptive Peptide Vaccine Targeting Sulfated Glycoprotein ZP2 of the Mouse Zona Pellucida1

1999 • 50 citations

Study of the immunopathogenesis of tubulointerstitial nephritis using model systems

1989 • 49 citations

Autoimmune Ovarian Inflammation Triggered by Proinflammatory (Th1) T Cells Is Compatible with Normal Ovarian Function in Mice1

1999 • 47 citations

Structural and Functional Aspects of the Interaction of Inflammatory Cells with the Blood-Brain Barrier in Experimental Brain Inflammation

1991 • 47 citations

Rapid induction of autoantibodies by endogenous ovarian antigens and activated T cells: implication in autoimmune disease pathogenesis and B cell tolerance.

1996 • 42 citations

Cell-to-cell communication in the ovarian follicle: developmental and hormonal regulation of the expression of connexin43

1998 • 33 citations

The blood-retinal barrier in experimental autoimmune uveoretinitis (EAU): a review

1992 • 30 citations

Induction, characterization, and cell transfer of autoimmune tubulointerstitial nephritis

1987 • 26 citations

Role of the target organ in determining susceptibility to experimental autoimmune myasthenia gravis

1998 • 20 citations

Macrophages in experimental autoimmune diseases in the rat: a review

1992 • 17 citations

Altered target organ. A mechanism of postrecovery resistance to murine autoimmune oophoritis.

1995 • 17 citations

Experimental allergic encephalomyelitis (EAE): Role of B cell and T cell epitopes in the development of EAE in lewis rats

1987 • 13 citations

Dose-dependency of MBP-induced demyelination in the guinea pig

1985 • 13 citations

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