Output Pathways Mediating Basal Ganglia Function

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Efferent connections of the substantia nigra and ventral tegmental area in the rat

1979 • 1,278 citations

The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat

1981 • 966 citations

Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining.

1978 • 741 citations

In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage

1978 • 599 citations

Stimulation of locomotor activity following injection of dopamine into the nucleus accumbens

1973 • 477 citations

Ibotenic acid-induced neuronal degeneration: A morphological and neurochemical study

1979 • 467 citations

Projections of the globus pallidus and adjacent structures: An autoradiographic study in the monkey

1976 • 411 citations

Evidence for a gabaergic projection from the substantia nigra to the ventromedial thalamus and to the superior colliculus of the rat

1979 • 397 citations

An immunohistochemical study of enkephalins and other neuropeptides in the striatum of the cat with evidence that the opiate peptides are arranged to form mosaic patterns in register with the striosomal compartments visible by acetylcholinesterase staining

1981 • 391 citations

Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat

1975 • 332 citations

An approach to tracing neuron networks in the cerebral cortex and basal ganglia. Combination of golgi staining, retrograde transport of horseradish peroxidase and anterograde degeneration of synaptic boutons in the same material

1979 • 329 citations

Evidence for the participation of nigrotectal γ-aminobutyrate-containing neurones in striatal and nigral-derived circling in the rat

1982 • 318 citations

Nucleus tegmenti pedunculopontinus: Efferent connections with special reference to the basal ganglia, studied in the rat by anterograde and retrograde transport of horseradish peroxidase

1983 • 307 citations

Mesolimbic dopaminergic neurones in the rotational model of nigrostriatal function

1976 • 296 citations

Specificity of 6-hydroxydopamine induced degeneration of central monoamine neurones: An electron and fluorescence microscopic study with special reference to intracerebral injection on the nigro-striatal dopamine system

1973 • 295 citations

Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

1976 • 294 citations

Organization of the nigrotectal connection: an experimental tracer study in the cat

1978 • 284 citations

Behavioural stimulation induced by muscimol and other GABA agonists injected into the substantia nigra

1977 • 279 citations

Projections of the pedunculopontine tegmental nucleus in the rat: evidence for additional extrapyramidal circuitry

1982 • 277 citations

The rotating rodent: A two component system?

1978 • 276 citations

Topography of choline acetyltransferase-containing neurons in the forebrain of the rat

1982 • 269 citations

Advances in pharmacology and chemotherapy

1969 • 269 citations

The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brain

1976 • 251 citations

Evidence suggesting secondary epileptogenic lesions after kainic acid: pretreatment with diazepam reduces distant but not local brain damage

1979 • 249 citations

Intranigral kainic acid is evidence that nigral non-dopaminergic neurones control posture

1977 • 243 citations

The organization of the efferent projections of the substantia nigra in the rat. A retrograde fluorescent double labeling study

1979 • 235 citations

Long-term central cholinergic hypofunction induced in mice by ethylcholine aziridinium ion (AF64A) in vivo.

1982 • 213 citations

Demonstration of nigrotectal and nigroreticular projections in the cat by axonal transport of proteins

1976 • 204 citations

Nigrotectal projections in the monkey: An autoradiographic study

1977 • 201 citations

The nigrotectal projection: a biochemical and ultrastructural characterization

1978 • 193 citations

Evidence for a GABAergic nigrothalamic pathway in the rat

1980 • 193 citations

Afferent connections of the zona incerta: A horseradish peroxidase study in the rat

1985 • 188 citations

5,7-Dihydroxytryptamine: Improvement in chemical lesioning of indoleamine neurons in the mammalian brain

1972 • 186 citations

A re-evaluation of the role of superior colliculus in turning behaviour

1982 • 186 citations

A histological study of kainic acid-induced lesions in the rat brain

1978 • 166 citations

Afferents to the periaqueductal gray in the rat. A horseradish peroxidase study

1983 • 161 citations

Feedback loop or output pathway in striato-nigral fibres?

1977 • 160 citations

Compartments in the striatum of the cat observed by retrograde cell labeling

1979 • 150 citations

The use of neurotoxic dihydroxytryptamines as tools for morphological studies and localized lesioning of central indolamine neurons

1973 • 145 citations

Afferent connections of the parvocellular reticular formation: A horseradish peroxidase study in the rat

1992 • 139 citations

The distribution and some morphological features of substantia nigra neurons that project to the thalamus, superior colliculus and pedunculopontine nucleus in the monkey

1982 • 138 citations

Pharmacology and Neurochemistry of Apomorphine

1978 • 128 citations

Striatal Efferent Fibers Play a Role in Maintaining Rotational Behavior in the Rat

1977 • 122 citations

A comparison of the intranigral distribution of nigrotectal neurons labeled with horseradish peroxidase in the monkey, cat, and rat.

1981 • 118 citations

Lesions in corpus striatum and cortex of rat brains and the effect on pharmacologically induced stereotyped, aggressive and cataleptic behaviour

1970 • 116 citations

Long collateral branches of substantia nigra pars reticulata axons to thalamus, superior colliculus and reticular formation in monkey and cat. Multiple retrograde neuronal labeling with fluorescent dyes

1983 • 116 citations

6-Hydroxydopamine lesions of olfactory tubercles and caudate nuclei: Effect on amphetamine-induced stereotyped behavior in rats

1974 • 116 citations

Electrophysiological evidence for branching nigral projections to the thalamus and the superior colliculus

1977 • 110 citations

A comparison of the intranigral distribution of nigrotectal neurons labeled with horseradish peroxidase in the monkey, cat, and rat

1981 • 110 citations

Role of GABA in the striatal output system: globus pallidus, nucleus entopeduncularis, substantia nigra and nucleus subthalamicus.

1981 • 106 citations

Dissociation of d-amphetamine-induced locomotor activity and stereotyped behaviour by lesions of the superior colliculus

1980 • 106 citations

Substantia nigra as an out-put station for striatal dopaminergic responses: Role of a GABA-mediated inhibition of pars reticulata neurons

1979 • 102 citations

Behavioural effects of GABA-agonists and antagonists infused in the mesencephalic reticular formation - deep layers of superior colliculus

1981 • 96 citations

Striatal evoked inhibition of identified nigro-thalamic neurons

1976 • 89 citations

Role of thalamic γ-aminobutyrate in motor functions: Catalepsy and ipsiversive turning after intrathalamic muscimol

1979 • 88 citations

Evidence that nigral GABA mediates behavioural responses elicited by striatal dopamine receptor stimulation

1978 • 84 citations

Superior colliculus lesions selectively attenuate apomorphine-induced oral stereotypy: a possible role for the nigrotectal pathway

1980 • 79 citations

Efferent projections of the deep mesencephalic nucleus (pars medialis) in the rat

1980 • 75 citations

GABA and the basal ganglia

1981 • 69 citations

The reticular formation revisited: specifying function for a nonspecific system

1980 • 67 citations

A method for simultaneous recording of eight behavioral parameters related to monoamine neurotransmission

1978 • 67 citations

Evidence that a nigral gabaergic-chrolinergic balance controls posture

1979 • 56 citations

Efferent projections of the deep mesencephalic nucleus (pars lateralis) in the rat

1980 • 56 citations

Evidence that the nigrotegmental GABAergic projection mediates stereotypy induced by apomorphine and intranigral muscimol

1983 • 52 citations

Role of dorsal mesencephalic reticular formation and deep layers of superior colliculus as out-put stations for turning behaviour elicited from the substantia nigra pars reticulata

1981 • 46 citations

Electrophysiological evidence for branching nigral projections to pontine reticular formation, superior colliculus and thalamus

1982 • 46 citations

The neurological basis of motor asymmetry following unilateral 6-hydroxydopamine brain lesions in the rat: the effect of motor decortication

1977 • 46 citations

Lesions of substantia nigra by kainic acid: Effects on apomorphine-induced stereotyped behaviour

1980 • 45 citations

Oral behaviour induced by intranigral muscimol is unaffected by haloperidol but abolished by large lesions of superior colliculus

1982 • 45 citations

Afferent connections of the mesencephalic reticular formation: A horseradish peroxidase study in the rat

1983 • 44 citations

Role of dorsal mesencephalic reticular formation and deep layers of superior colliculus in turning behaviour elicited from the striatum

1981 • 42 citations

Afferent projections to the deep mesencephalic nucleus in the rat

1982 • 40 citations

Role of the ventromedial nucleus of the thalamus in motor behaviour—I. Effects of focal injections of drugs

1983 • 39 citations

Basal ganglia outflow pathways and circling behaviour in the rat

1983 • 39 citations

The neurological basis of motor asymmetry following unilateral nigrostriatal lesions in the rat: the effect of secondary superior colliculus lesions

1978 • 37 citations

The anatomical substrate of the turning behaviour seen after lesions in the nigrostriatal dopamine system

1983 • 37 citations

Dopamine-mediated circling behaviour does not involve the nigro-tectal pathway

1979 • 36 citations

Role of GABA neurons in the expression of striatal motor functions.

1981 • 32 citations

Distribution of γ-aminobutyrate in the rat thalamus: Specific decreases in thalamic γ-aminobutyrate following lesion or electrical stimulation of the substantia nigra

1981 • 32 citations

Role of substantia nigra pars reticulata neurons in the expression of neuroleptic-induced catalepsy

1981 • 30 citations

Ipsiversive turning behaviour after discrete unilateral lesions of the dorsal mesencephalic reticular formation by kainic acid

1981 • 30 citations

Role of the ventromedial nucleus of the thalamus in motor behaviour—II. Effects of lesions

1983 • 28 citations

A freeze‐fracture study of intercellular junctions between various kinds of epithelial cells surrounding common endolymphatic space in the hearing organ of the chick

1980 • 27 citations

Nigro-reticular pathway in the rat: an intracellular study

1981 • 26 citations

Suppression of apomorphine-induced oral stereotypy in rats by microinjection of muscimol into midbrain

1982 • 26 citations

The role of nigral projections to the thalamus in drug-induced circling behaviour in the rat

1981 • 19 citations

Redundancy in ascending and descending pathways mediating head turning elicited by entopenduncular stimulation in the cat

1983 • 17 citations

Drug-induced circling after unilateral 6-hydroxydopamine lesions of the nigro-striatal pathway is mediated via the midbrain periaqueductal grey and adjacent reticular formation (angular complex)

1981 • 14 citations

Investigation of the connection between the substantia nigra and the medullary reticular formation in the rat

1983 • 13 citations

Study of the neural basis of circling behavior induced by l-DOPA in lesioned entopeduncular cats

1982 • 9 citations