Establishment and characterization of a novel acute promyelocytic leukemia cell line (UF-1) with retinoic acid-resistant features

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1988 • 2,380 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1991 • 1,298 citations

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments]

1990 • 1,224 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)

1991 • 884 citations

Role of retinoids in differentiation and carcinogenesis.

1983 • 780 citations

Acute Promyelocytic Leukemia

2015 • 764 citations

Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

1983 • 585 citations

Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

1990 • 330 citations

Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: comparison with recombinant human granulocyte-macrophage colony-stimulating factor

1987 • 216 citations

Expression of cellular retinoic acid binding protein (CRABP) in Escherichia coli. Characterization and evidence that holo-CRABP is a substrate in retinoic acid metabolism.

1991 • 202 citations

Resistance to all-trans retinoic acid (ATRA) therapy in relapsing acute promyelocytic leukemia: study of in vitro ATRA sensitivity and cellular retinoic acid binding protein levels in leukemic cells [see comments]

1993 • 191 citations

Retinoid resistance in acute promyelocytic leukemia: new mechanisms, strategies, and implications [editorial; comment]

1993 • 190 citations

Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity

1992 • 190 citations

CD7+, CD4-, CD8- acute leukemia: a syndrome of malignant pluripotent lymphohematopoietic cells

1989 • 156 citations

Prognostic value of lymphocyte surface markers in acute myeloid leukemia [see comments]

1991 • 149 citations

A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell.

1990 • 134 citations

Clinical importance of CD7 expression in acute myelocytic leukemia. The Japan Cooperative Group of Leukemia/Lymphoma [see comments]

1993 • 116 citations

CD 7 positive acute myeloid leukaemia: a subtype associated with cell immaturity

1989 • 105 citations

Mechanisms of retinoid resistance in leukemic cells: possible role of cytochrome P450 and P-glycoprotein

1996 • 103 citations

Leukemia cell lines: In vitro models for the study of acute promyelocytic leukemia

1995 • 95 citations

A retinoid acid 'resistant' t(15;17) acute promyelocytic leukemia cell line: isolation, morphological, immunological, and molecular features.

1992 • 89 citations

Clinical importance of CD7 expression in acute myelocytic leukemia. The Japan Cooperative Group of Leukemia/Lymphoma

1993 • 64 citations

CD7+ acute non-lymphocytic leukemia: Evidence for an early multipotential progenitor

1990 • 56 citations

Characterization of differentiation-inducer-resistant HL-60 cells

1985 • 41 citations

In vivo and in vitro activity of neutrophil alkaline phosphatase in acute myelocytic leukemia with 8;21 translocation

1981 • 38 citations

Giant Mitochondria with Filamentous Structures in Bone Marrow Macrophages

1985 • 10 citations