Regulation of gene expression for translation initiation factor eIF-2α: importance of the 3′ untranslated region

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Genomic sequencing.

1984 • 8,343 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Poly(A) signals

1991 • 438 citations

Control of Messenger RNA Stability

1993 • 394 citations

THE BIOCHEMISTRY OF 3′-END CLEAVAGE AND POLYADENYLATION OF MESSENGER RNA PRECURSORS

1992 • 387 citations

AUUUA Is Not Sufficient To Promote Poly(A) Shortening and Degradation of an mRNA: the Functional Sequence within AU-Rich Elements May Be UUAUUUA(U/A)(U/A)

1994 • 331 citations

How RNA polymerase II terminates transcription in higher eukaryotes

1989 • 301 citations

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation.

1984 • 282 citations

Regulation of protein synthesis initiation in eucaryotes

1983 • 227 citations

2B or not 2B: Regulation of the catalytic utilization of elF-2

1983 • 172 citations

The AU-rich sequences in the 3' untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids.

1991 • 170 citations

Erythroid Cell-Specific mRNA Stability Elements in the α2-Globin 39 Nontranslated Region

1995 • 167 citations

Cloning and sequencing of complementary DNAs encoding the alpha-subunit of translational initiation factor eIF-2. Characterization of the protein and its messenger RNA.

1987 • 110 citations

The HTLV-I rex response element mediates a novel form of mRNA polyadenylation

1991 • 101 citations

Complete thrombospondin mRNA sequence includes potential regulatory sites in the 3' untranslated region.

1989 • 72 citations

3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes.

1993 • 71 citations

Regulation of translation initiation factor gene expression during human T cell activation.

1992 • 64 citations

Alternative poly(A) site utilization during adenovirus infection coincides with a decrease in the activity of a poly(A) site processing factor.

1993 • 54 citations

Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals.

1988 • 53 citations

Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements.

1993 • 52 citations

Identification of the 1.4 KB and 4.0 KB messages for the lipoprotein associated coagulation inhibitor and expression of the encoded protein

1989 • 46 citations

The end of the message: 3'– end processing leading to polyadenylated messenger RNA

1992 • 44 citations

Increased eIF-2 alpha expression in mitogen-activated primary T lymphocytes.

1990 • 43 citations

Sequence elements upstream of the 3' cleavage site confer substrate strength to the adenovirus L1 and L3 polyadenylation sites.

1994 • 40 citations

Identification of a functional role for the 3′ region of the human oestrogen receptor gene

1993 • 39 citations

Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.

1994 • 34 citations

3' RNA Processing Efficiency Plays a Primary Role in Generating Termination-Competent RNA Polymerase II Elongation Complexes

1993 • 33 citations

Spatial constraints on polyadenylation signal function.

1990 • 30 citations

Isolation and characterization of the promoter and flanking regions of the gene encoding the human protein-synthesis-initiation factor 2α

1989 • 27 citations

Polyadenylation and transcription termination in gene constructs containing multiple tandem polyadenylation signals

1994 • 27 citations

Patterns of Polyadenylation Site Selection in Gene Constructs Containing Multiple Polyadenylation Signals

1988 • 26 citations

Heterogeneity in the 5′ untranslated region of mouse cytochrome c_TmRNAs leads to altered translational status of the mRNAs

1994 • 25 citations

Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16.

1991 • 23 citations

Use of a continuous‐flow cell separator in density gradient isolation of lymphocytes

1987 • 21 citations

Characterization of the Mouse β^maj Globin Transcription Termination Region: a Spacing Sequence is Required Between the Poly(A) Signal Sequence and Multiple Downstream Termination Elements

1993 • 21 citations

RNA 3'-end formation

1989 • 20 citations

Translation in vivo and in vitro of mRNAs Coding for Vitellogenin, Serum Albumin and Very-Low-Density Lipoprotein II from Chicken Liver. A Difference in Translational Efficiency

1981 • 20 citations

Alternative Poly(A) Site Utilization during Adenovirus Infection Coincides with a Decrease in the Activity of a Poly(A) Site Processing Factor

1993 • 18 citations

Different Forms of G_oα mRNA Arise by Alternative Splicing of Transcripts from a Single Gene on Human Chromosome 16

1991 • 5 citations

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