PROTEOLYTIC EVENTS IN VIRAL REPLICATION

Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity by proteolytic cleavage of an inactive precursor protein of Sendai virus

1974 • 931 citations

Activation of influenza A viruses by trypsin treatment

1975 • 831 citations

Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus

1976 • 651 citations

Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide

1975 • 602 citations

Complement

1975 • 594 citations

Trypsin Action on the Growth of Sendai Virus in Tissue Culture Cells III. Structural Difference of Sendai Viruses Grown in Eggs and Tissue Culture Cells

1973 • 520 citations

A protein covalently linked to poliovirus genome RNA.

1977 • 424 citations

Role of proteolytic enzymes in biological regulation (a review).

1976 • 410 citations

Basic Mechanisms in Blood Coagulation

1975 • 366 citations

Polypeptide cleavages in the formation of poliovirus proteins.

1968 • 353 citations

Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus.

1977 • 344 citations

In vitro synthesis and processing of a putative precursor for the small subunit of ribulose-1,5-bisphosphate carboxylase of Chlamydomonas reinhardtii.

1977 • 332 citations

Proteolytic cleavage of bacteriophage lambda repressor in induction.

1975 • 326 citations

Further evidence on the formation of poliovirus proteins

1970 • 312 citations

Generation of avian myeloblastosis virus structural proteins by proteolytic cleavage of a precursor polypeptide

1975 • 308 citations

Homology in amino-terminal sequence of precursors to pancreatic secretory proteins.

1975 • 272 citations

The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.

1976 • 271 citations

Morphogenesis of poliovirus

1968 • 263 citations

Evidence for large precursor proteins in poliovirus synthesis.

1968 • 253 citations

5'-terminal structure of poliovirus polyribosomal RNA is pUp.

1976 • 247 citations

Water in Biological Systems

1971 • 242 citations

RNA metabolism of murine leukemia virus: Detection of virus-specific RNA sequences in infected and uninfected cells and identification of virus-specific messenger RNA

1973 • 223 citations

Sodium ions and the shut-off of host cell protein synthesis by picornaviruses

1976 • 222 citations

Activation of precursors to both glycoproteins of Newcastle disease virus by proteolytic cleavage

1977 • 207 citations

Zinc ions inhibit replication of rhinoviruses

1974 • 199 citations

FUSION OF CULTURED MULTIPLE-SCLEROSIS BRAIN CELLS WITH INDICATOR CELLS: PRESENCE OF NUCLEOCAPSIDS AND VIRIONS AND ISOLATION OF PARAINFLUENZA-TYPE VIRUS

1972 • 195 citations

Protease activation mutants of Sendai virus

1976 • 169 citations

Cleavage of Rous sarcoma viral polypeptide precursor into internal structural proteins in vitro involves viral protein p15.

1977 • 167 citations

Three structural polypeptides coded for by minite virus of mice, a parvovirus

1976 • 158 citations

Specific cleavage of viral proteins as steps in the synthesis and maturation of enteroviruses.

1968 • 156 citations

Identification of a Large Polypeptide Precursor of Avian Oncornavirus Proteins

1973 • 145 citations

Studies on the assembly of the envelope of Newcastle disease virus

1976 • 145 citations

Biosynthesis of Rauscher leukemia viral proteins: Presence of p30 and envelope p15 sequences in precursor polypeptides

1976 • 144 citations

Translation of Sindbis virus 26 S RNA and 49 S RNA in lysates of rabbit reticulocytes

1974 • 144 citations

Bacteriophage T4 prehead proteinase

1976 • 140 citations

Competition between cellular and viral mRNAs in vitro is regulated by a messenger discriminatory initiation factor.

1976 • 138 citations

Encephalomyocarditis Virus Infection of Mouse Plasmacytoma Cells I. Inhibition of Cellular Protein Synthesis

1974 • 128 citations

Effect of Pactamycin on Synthesis of Poliovirus Proteins: a Method for Genetic Mapping

1971 • 127 citations

How a single sindbis virus mRNA directs the synthesis of one soluble protein and two integral membrane glycoproteins

1977 • 124 citations

Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus: Synthesis, identification, and processing

1976 • 122 citations

Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus

1975 • 121 citations

Structural difference between the 5' termini of viral and cellular mRNA in poliovirus-infected cells: possible basis for the inhibition of host protein synthesis

1976 • 120 citations

Presence of murine leukemia virus envelope proteins gp70 and p15(E) in a common polyprotein of infected cells

1976 • 118 citations

Translation of murine leukemia virus RNA in cell-free systems from animal cells

1976 • 116 citations

Characterization of the Large Picornaviral Polypeptides Produced in the Presence of Zinc Ion

1974 • 116 citations

Virus-Specific Proteins Synthesized in Encephalomyocarditis Virus-Infected HeLa Cells

1971 • 114 citations

High molecular weight precursor polypeptides to structural proteins of Rauscher murine leukemia virus

1976 • 113 citations

Trypsin Action on the Growth of Sendai Virus in Tissue Culture Cells

1971 • 112 citations

A protease inhibitor blocks SOS functions in Escherichia coli: antipain prevents lambda repressor inactivation, ultraviolet mutagenesis, and filamentous growth.

1977 • 112 citations

Synthesis of Avian RNA Tumor Virus Structural Proteins

1974 • 110 citations

Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides

1976 • 106 citations

Structural Studies of Avian Myeloblastosis Virus: Comparison of Polypeptides in Virion and Core Component by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1974 • 100 citations

Cleavage of Viral Precursor Proteins In Vivo and In Vitro

1972 • 100 citations

Translation of poliovirus RNA in vitro: Detection of two different initiation sites

1975 • 96 citations

Bacteriophage T4 prehead proteinase

1976 • 95 citations

A fucose-deficient glycoprotein precursor to Rauscher leukemia virus gp69/71.

1976 • 94 citations

Vaccinia Virus Structural Polypeptide Derived from a High-Molecular-Weight Precursor: Formation and Integration into Virus Particles

1970 • 93 citations

Post-Translational Cleavage of Polypeptide Chains: Role in Assembly

1975 • 91 citations

Cytoplasm from Poliovirus-infected HeLa Cells inhibits Cell-free Haemoglobin Synthesis

1971 • 90 citations

Complete translation of poliovirus RNA in a eukaryotic cell-free system.

1975 • 90 citations

Cell-free translation of virion RNA from nondefective and transformation-defective Rous sarcoma viruses

1976 • 88 citations

Isolation of a Viral Polypeptide Associated with Poliovirus RNA Polymerase

1974 • 88 citations

Murine leukemia virus mutants with temperature-sensitive defects in precursor polypeptide cleavage

1975 • 87 citations

Synthesis and Cleavage of Enterovirus Polypeptides in Mammalian Cells

1970 • 86 citations

The Initiation of Protein Synthesis Directed by the RNA from Encephalomyocarditis Virus

1973 • 85 citations

A core polyprotein of murine leukemia virus on the surface of mouse leukemia cells

1976 • 77 citations

Maturation of the head of bacteriophage T4. V. A possible DNA packaging mechanism: In vitro cleavage of the head proteins and the structure of the core of the polyhead

1974 • 76 citations

Sequential translation of nonstructural proteins in cells infected with a Semliki Forest virus mutant.

1976 • 76 citations

Structure and Molecular Weight of the 60-70S RNA and the 30-40S RNA of the Rous Sarcoma Virus

1974 • 74 citations

Kinetics of synthesis and cleavage of encephalomyocarditis virus-specific proteins

1972 • 71 citations

Inhibition of Cleavage of Large Poliovirus-Specific Precursor Proteins in Infected HeLa Cells by Inhibitors of Proteolytic Enzymes

1972 • 70 citations

Determination of the Gene Sequence of Poliovirus with Pactamycin

1971 • 69 citations

Viral proteins expressed on the surface of murine leukemia cells

1977 • 68 citations

Identification of a Precursor Protein to the Major Glycoproteins of Mouse Mammary Tumor Virus

1976 • 67 citations

Tryptic peptide analysis on nonstructural and structural precursor proteins from Semliki Forest virus mutant-infected cells

1975 • 66 citations

Monomer molecular weight of T antigen from simian virus 40-infected and transformed cells.

1976 • 65 citations

Investigation of the structure of polio- and human rhinovirions through the use of selective chemical reactivity

1976 • 64 citations

Gene 21 protein-dependent proteolysis in vitro of purified gene 22 product of bacteriophage T4

1975 • 62 citations

Cleavage of Poliovirus-Specific Polypeptide Aggregates

1973 • 60 citations

Fractionation of biologically active and inactive populations of human rhinovirus type 2

1975 • 59 citations

Murine Type-C Virus Group-Specific Antigens: Interstrain Immunochemical, Biophysical, and Amino Acid Sequence Differences

1974 • 59 citations

Translation of Semliki-Forest-Virus Intracellular 26-S RNA. Characterisation of the Products Synthesized in vitro

1975 • 59 citations

Formation of Sindbis Virus Capsid Protein in Mammalian Cell-Free Extracts Programmed with Viral Messenger RNA

1974 • 59 citations

Formation of Influenza Virus Proteins

1973 • 56 citations

Inhibition of initiation of protein synthesis in mammalian tissue culture cells by L-1-tosylamido-2-phenylethyl chloromethyl ketone.

1975 • 55 citations

A Proposed Regulator for Poliovirus: The Equestron

1973 • 52 citations

PHYSICAL AND IMMUNOLOGICAL PROPERTIES OF A SOLUBLE PRECURSOR OF THE POLIOVIRUS CAPSID

1964 • 52 citations

Synthesis and processing of the precursor to the major core protein of adenovirus type 2

1977 • 51 citations

Reverse Transcriptase and RNase H: Present in a Murine Virus and in Both Subunits of an Avian Virus

1974 • 51 citations

Selective decrease in the rate of cleavage of an intracellular precursor to Rauscher leukemia virus p30 by treatment of infected cells with actinomycin D

1976 • 51 citations

Synthesis of viral-specific polypeptides in Mengo virus-infected L cells: Evidence for asymmetric translation of the viral genome

1974 • 51 citations

Identification of a viral protein involved in post-translational maturation of the encephalomyocarditis virus capsid precursor

1975 • 50 citations

Animal RNA Viruses: Genome Structure and Function

1974 • 48 citations

Protein cleavage during virus assembly: Characterization of cleavage in T4 phage

1975 • 45 citations

A Model for Foot-and-Mouth Disease Virus

1972 • 42 citations

Components in T4-infected cells associated with phage assembly

1966 • 42 citations

Cells transformed by certain strains of moloney sarcoma virus contain murine p60

1977 • 42 citations

Isolation and Properties of the Replicase of Encephalomyocarditis Virus

1976 • 41 citations

Evidence for the existence of protomers in the assembly of encephalomyocarditis virus

1975 • 41 citations

A p60 polypeptide in the feline leukemia virus pseudotype of Moloney sarcoma virus with murine leukemia virus p30 antigenic determinants.

1975 • 41 citations

Cleavage of Mengovirus Polyproteins In Vivo

1974 • 40 citations

Defective cleavage of a precursor polypeptide in a temperature-sensitive mutant of avian sarcoma virus

1976 • 39 citations

Sensitive, solid-phase assay of proteolytic activity

1976 • 38 citations

Trypsin action on the growth of Sendai virus in tissue culture cells. IV. Evidence for activation of sendai virus by cleavage of a glycoprotein

1976 • 38 citations

INHIBITION OF VIRAL RNA SYNTHESIS BY PARAFLUOROPHENYLALANINE

1961 • 38 citations

Replication of rhinoviruses

1976 • 36 citations

Changes in ribosomal proteins associated with mutants in a locus that affects Escherichia coli ribosomes

1968 • 35 citations

Proteinase activity in purified animal viruses

1972 • 35 citations

Two active forms of RD-114 virus DNA polymerase in infected cells

1975 • 34 citations

Cleavage of Virus-specified Polypeptides in Cells Infected with Semliki Forest Virus

1974 • 33 citations

Inhibition of Sindbis virus replication by zinc lons

1976 • 33 citations

Structure of the Mengo virion

1976 • 32 citations

Evidence of ambiguous processing and selective degradation in the noncapsid proteins of rhinovirus 1A

1976 • 31 citations

The Synthesis of Encephalomyocarditis Virus Polypeptides in Infected L-Cells and Cell-Free Systems

1974 • 30 citations

Effect of temperature on the cleavage of polypeptides during growth of LSc poliovirus

1971 • 29 citations

Primary structure of bacteriophage T4 internal protein II and characterization of the cleavage upon phage maturation

1976 • 29 citations

Formation of a Sindbis virus nonstructural protein and its relation of 42S mRNA function

1976 • 29 citations

RNA Virus Gene Expression and its Control

1972 • 29 citations

Early synthesis of Semliki Forest virus-specific proteins in infected chicken cells

1976 • 27 citations

Chemical modification of DNA polymerase phosphoprotein from avian myeloblastosis virus

1977 • 25 citations

Protein cleavage during virus assembly: a novel specificity of assembly dependent cleavage in bacteriophage T4.

1976 • 25 citations

In vitro assembly of polioviruses

1973 • 25 citations

T4-Induced Activity Required for Specific Cleavage of a Bacteriophage Protein In Vitro

1974 • 24 citations

Synthesis and Cleavage of Influenza Virus Proteins

1971 • 23 citations

Picornaviral capsid assembly: similarity of rhinovirus and enterovirus precursor subunits

1977 • 23 citations

Cleavage site alterations in poliovirus-specific precursor proteins

1976 • 21 citations

Poliovirus Polypeptides Examined in More Detail

1975 • 21 citations

Structural proteins of polyoma virus: proteolytic degradation of virion proteins by exogenous and by virion-associated proteases

1976 • 19 citations

Protease activity associated with HeLa cell ribosomes

1977 • 19 citations

Cell-Free Translation of Foot-and-Mouth Disease Virus RNA into Identifiable Non-capsid and Capsid Proteins

1976 • 18 citations

Analysis of intracellular feline leukemia virus proteins. I. Identification of a 60,000-dalton precursor of feline leukemia virus p30

1976 • 17 citations

Identification of gene products required for in vitro formation of the internal peptides of bacteriophage T4

1976 • 16 citations

Studies on phage internal proteins

1974 • 16 citations

Virus-specific Polypeptides in Ascites Cells Infected with Encephalomyocarditis Virus

1972 • 16 citations

Relations Between Poliovirus Polypeptides as shown by Tryptic Peptide Analysis

1975 • 15 citations

Antigenic Specificity of Poliovirus-Related Particles

1971 • 14 citations

Studies on the nonneutralizable fraction of poliovirus

1972 • 14 citations

Proteins specified by Sindbis virus in chick embryo fibroblast cells

1973 • 13 citations

Processing of mengovirus precursor polypeptides in the presence of zinc ions and sulfhydryl compounds

1976 • 12 citations

The electrophoretic mobilites of adapted MEF1 poliomyelitis virus and its soluble antigen

1957 • 11 citations

Reversible Inhibition of Poliovirus RNA Synthesis In Vivo and In Vitro by Viral Products

1974 • 11 citations

Parainfluenza 1 virus and multiple sclerosis: The conversion of 6/94 virus released from human brain cells and other mammalian cells into and infectious form by passage in macrophages

1974 • 10 citations

Lysosomal Enzyme Activity in Poliovirus-infected HeLa Cells and Vesicular Stomatitis Virus-infected L Cells: biochemical and Histochemical Comparative Analysis with Computer-aided Techniques

1974 • 10 citations

Evidence for control of translation of the viral genome during replication of Mengo virus and poliovirus

1975 • 10 citations

Host restriction of Friend Leukemia virus coat protein synthesis

1976 • 9 citations

Tosyl lysine chloromethyl ketone inhibition of the initiation of hemoglobin synthesis

1973 • 8 citations

Bacteriophage T4D-induced proteinase

1974 • 7 citations

The potential role of phagocytically active cells in establishing chronic parainfluenza 1 virus infections in human brain

1975 • 5 citations

Proteins Specified by Sindbis Virus in HeLa Cells

1974 • 4 citations

Kinetic evidence for the processing of ribosomal proteins S6 and S8

1976 • 4 citations

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