Interindividual Variation in the DNA Binding of Chemical Genotoxins Following Metabolism by Human Bladder and Bronchus Explants

IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

1980 • 3,166 citations

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.

1977 • 507 citations

Tumours Of The Urinary Bladder in Workmen Engaged in the Manufacture and Use Of Certain Dyestuff Intermediates In The British Chemical Industry. Part I. The Role Of Aniline, Benzidine, Alpha-Naphthylamine, And Beta-Naphthylamine

1954 • 425 citations

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

1979 • 412 citations

Dietary aflatoxins and liver cancer – a population based study in Kenya

1973 • 304 citations

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.

1978 • 246 citations

Carcinogenic effects of low dietary levels of aflatoxin B1 in rats

1974 • 215 citations

Dietary aflatoxins and human liver cancer. IV. Incidence of primary liver cancer in two municipal populations of Thailand

1972 • 165 citations

Polymorphisms of Oxidation at Carbon Centers of Drugs and Their Clinical Significance

1979 • 163 citations

Smoking and Cancer of the Lower Urinary Tract

1971 • 159 citations

Metabolism of benzo[a]pyrene

1975 • 148 citations

The effect of added dietary tryptophane on the occurrence of 2-acetylaminofluorene-induced liver and bladder cancer in rats.

1950 • 140 citations

Interindividual Variation in Binding of Benzo[ a ]pyrene to DNA in Cultured Human Bronchi

1976 • 138 citations

Effects of physical training in intermittent claudication

1978 • 135 citations

Experimental Tobacco Carcinogenesis

1968 • 115 citations

Metabolism of benzo(a)pyrene and identification of the major benzo(a)pyrene-DNA adducts in cultured human colon.

1978 • 107 citations

Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans

1980 • 102 citations

Long-term organ culture of human bronchial epithelium.

1976 • 80 citations

Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon.

1979 • 75 citations

In vitro metabolic conversion of aflatoxins and benzo(alpha)pyrene to nucleic acid-binding metabolites.

1975 • 72 citations

Metabolism of benzo(a)pyrene, N-nitrosodimethylamine, and N-nitrosopyrrolidine and identification of the major carcinogen-DNA adducts formed in cultured human esophagus.

1979 • 70 citations

Excision repair of aflatoxin B1-DNA adducts in human fibroblasts.

1981 • 69 citations

Metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in cultured human bronchus and pancreatic duct.

1977 • 65 citations

Chapter 2 Identification and Culture of Human Bronchial Epithelial Cells

1980 • 51 citations

Covalent interaction of carcinogens with DNA

1975 • 50 citations

Comparison of benzo(a)pyrene metabolism in bronchus, esophagus, colon, and duodenum from the same individual.

1982 • 49 citations

Explant culture of human peripheral lung. I. Metabolism of benzo[alpha]pyrene.

1978 • 49 citations

Large interindividual variations in metabolism of benzo(α)pyrene by peripheral lung tissue from lung cancer patients

1979 • 48 citations

High blood pressure related to carcinogen-induced unscheduled DNA synthesis, DNA carcinogen binding, and chromosomal aberrations in human lymphocytes.

1976 • 48 citations

Spontaneous reactions of aflatoxin B1 modified deoxyribonucleic acid in vitro

1980 • 47 citations

A high pressure liquid chromatography study on the removal of DNA-bound aflatoxin B¹ in rat liver and in vitro

1980 • 47 citations

Mechanisms of Chemical Carcinogenesis

1983 • 46 citations

Metabolism and DNA binding of benzo[a]pyrene in cultured human bladder and bronchus

1982 • 46 citations

Comparison of the hydroxylation of benzo(a)pyrene with the metabolism of vinyl chloride, N-nitrosomorpholine, and N-nitroso-N'-methylpiperazine to mutagens by human and rat liver microsomal fractions.

1980 • 44 citations

The Biology and Clinical Management of Bladder Cancer.

1976 • 44 citations

The activation of aflatoxin B₁ in liver slices and in bacterial mutagenicity assays using livers from different species including man

1981 • 40 citations

Formation and removal of aflatoxin B1-induced DNA lesions in epithelioid human lung cells.

1979 • 38 citations

Metabolism and binding of benzo(a)pyrene and 2-acetylaminofluorene by short-term organ cultures of human and rat bladder.

1982 • 36 citations

Carcinogenicity of Aflatoxin B1 in Rhesus Monkeys: Two Additional Cases of Primary Liver Cancer2

1976 • 35 citations

Interspecies comparisons of benzo(a)pyrene metabolism and DNA-adduct formation in cultured human and animal bladder and tracheobronchial tissues.

1983 • 32 citations

Metabolism of dimethylnitrosamine and 1,2-dimethylhydrazine in cultured human bronchi.

1977 • 31 citations

Factors influencing the induction of tumours of the urinary bladder and liver by 2-acetylaminofluorene in the mouse

1969 • 30 citations

In vitro reaction of radioactive 7β,8α,-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene and 7β,8α-dihydroxy-9β,10β-epoxy-7,8,9,10-tetrahydrobenzo(A)pyrene with DNA

1977 • 29 citations

Induction of hepatic carcinoma with aflatoxin in the rhesus monkey

1972 • 28 citations

DNA binding and adduct formation of aflatoxin B₁ in cultured human and animal tracheobronchial and bladder tissues

1982 • 28 citations

Metabolism of aflatoxin B₁, benzo[a]pyrene, and 1,2‐dimethylhydrazine by cultured rat and human colon

1981 • 27 citations

Aryl Hydrocarbon Hydroxylase in Human Bronchial Epithelium and Blood Monocyte<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref><xref ref-type="fn" rid="fn4">4</xref>

1981 • 20 citations

The in vitro oxidative metabolism of benzo(a)pyrene in human liver measured by different assays

1977 • 19 citations

Pharmacogenetics

1975 • 17 citations