Binding characteristics of scavenger receptors on liver endothelial and Kupffer cells for modified low-density lipoproteins

Beyond Cholesterol

1989 • 6,533 citations

Efficient Trace-labelling of Proteins with Iodine

1958 • 2,571 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

Determination of free amino groups in proteins by trinitrobenzenesulfonic acid

1966 • 2,029 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

Separation of plasma lipoproteins by density-gradient ultracentrifugation

1975 • 1,114 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

1980 • 851 citations

The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages

1980 • 543 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

In vivo and in vitro uptake and degradation of acetylated low density lipoprotein by rat liver endothelial, Kupffer, and parenchymal cells.

1983 • 396 citations

Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein.

1985 • 388 citations

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.

1991 • 386 citations

Specificity of receptor-mediated recognition of malondialdehyde-modified low density lipoproteins.

1982 • 279 citations

Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells

1991 • 275 citations

Charged collagen structure mediates the recognition of negatively charged macromolecules by macrophage scavenger receptors.

1993 • 243 citations

The complete cDNA and amino acid sequence of human apolipoprotein B-100.

1986 • 227 citations

Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts.

1991 • 219 citations

Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells.

1985 • 219 citations

The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands.

1993 • 150 citations

Rat liver Kupffer and endothelial cells express different binding proteins for modified low density lipoproteins. Kupffer cells express a 95-kDa membrane protein as a specific binding site for oxidized low density lipoproteins.

1994 • 70 citations

Coupling of the antiviral drug ara-AMP to lactosaminated albumin leads to specific uptake in rat and human hepatocytes

1993 • 44 citations

In vivo fate and scavenger receptor recognition of oxidized lipoprotein[a] isoforms in rats.

1992 • 38 citations