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Influence of Testosterone on the GH—IGF-I Axis in Healthy Elderly Men

Data up to Jan 2025

Published1999
Citations8
References55

Total Citations Per Year

Abstract

References (55)

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Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men.

1992 • 154 citations

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1994 • 141 citations

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1992 • 140 citations

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1987 • 130 citations

Estrogen and Testosterone, But Not a Nonaromatizable Androgen, Direct Network Integration of the Hypothalamo-Somatotrope (Growth Hormone)-Insulin-Like Growth Factor I Axis in the Human: Evidence from Pubertal Pathophysiology and Sex-Steroid Hormone Replacement

1997 • 122 citations

Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay

1995 • 118 citations

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1987 • 98 citations

Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass

1992 • 84 citations

Estrogen receptor blockade with tamoxifen diminishes growth hormone secretion in boys: evidence for a stimulatory role of endogenous estrogens during male adolescence

1994 • 76 citations

Growth hormone (GH)-releasing hormone-(1-29) twice daily reverses the decreased GH and insulin-like growth factor-I levels in old men

1992 • 74 citations

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1998 • 73 citations

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1993 • 73 citations

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1996 • 70 citations

Maturation of the Regulation of Growth Hormone Secretion in Young Males with Hypogonadotropic Hypogonadism Pharmacologically Exposed to Progressive Increments in Serum Testosterone

1997 • 69 citations

Tamoxifen attenuates pulsatile growth hormone secretion: mediation in part by somatostatin.

1992 • 65 citations

Short-Term Modulation of the Androgen Milieu Alters Pulsatile, But Not Exercise- or Growth Hormone (GH)-Releasing Hormone-Stimulated GH Secretion in Healthy Men: Impact of Gonadal Steroid and GH Secretory Changes on Metabolic Outcomes1

1997 • 62 citations

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1993 • 57 citations

Activation of the somatotropic axis by testosterone in adult males: evidence for the role of aromatization

1993 • 51 citations

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1993 • 50 citations

Transcriptional regulation of rat P-450 2C gene subfamily members by the sexually dimorphic pattern of growth hormone secretion

1992 • 45 citations

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Androgen receptor blockade with flutamide enhances growth hormone secretion in late pubertal males: evidence for independent actions of estrogen and androgen

1993 • 39 citations

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1996 • 34 citations

Short-Term Modulation of the Androgen Milieu Alters Pulsatile, But Not Exercise- or Growth Hormone (GH)-Releasing Hormone-Stimulated GH Secretion in Healthy Men: Impact of Gonadal Steroid and GH Secretory Changes on Metabolic Outcomes

1997 • 33 citations

Effect of Estrogen on the Growth Hormone Response to theα-Adrenergic Agonist Clonidine in Women with Menopausal Flushing*

1987 • 28 citations

Serum IGF-Binding Protein-3 is Related to IGF-I, But Not to Spontaneous GH Release, in Healthy Old Men

1992 • 28 citations

Effects of sex and age on the growth hormone response to galanin in healthy human subjects

1993 • 27 citations

Growth hormone binding protein in the rat: effects of gonadal steroids

1993 • 26 citations

Estradiol inhibits growth hormone receptor gene expression in rabbit liver

1994 • 26 citations

Tamoxifen attenuates pulsatile growth hormone secretion: mediation in part by somatostatin

1992 • 23 citations

Androgens Do Not Regulate the Growth Hormone Response to GHRH in Elderly Men

1989 • 10 citations

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