Zinc Fingers and Metallothionein in Gene Expression

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

METALLOTHIONEIN

1986 • 1,606 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Biochemistry of metallothionein

1988 • 1,222 citations

[69] Overview of metallothionein

1991 • 793 citations

‘Zinc fingers’: a novel protein motif for nucleic acid recognition

1987 • 676 citations

DNA recognition by GAL4: structure of a protein-DNA complex

1992 • 664 citations

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

1990 • 609 citations

Developmental biology : a comprehensive synthesis

1985 • 580 citations

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

1988 • 522 citations

Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein.

1986 • 518 citations

Zinc fingers and other metal-binding domains. Elements for interactions between macromolecules.

1990 • 509 citations

Solution structure of the DMA-binding domain of the oestrogen receptor

1990 • 458 citations

Metallothioneins: Proteins in search of function

1985 • 445 citations

Xenopus transcription factor A requires zinc for binding to the 5 S RNA gene.

1983 • 356 citations

Identification and preliminary characterization of a protein motif related to the zinc finger.

1993 • 327 citations

MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination.

1992 • 291 citations

Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Spl

1991 • 252 citations

EXAFS study of the zinc-binding sites in the protein transcription factor IIIA

1986 • 247 citations

Handbook of Metal-Ligand Interactions in Biological Fluids

1995 • 243 citations

A consensus zinc finger peptide: design, high-affinity metal binding, a pH-dependent structure, and a His to Cys sequence variant

1991 • 237 citations

DNA binding specificity of steroid receptors

1989 • 212 citations

GAL4 transcription factor is not a "zinc finger" but forms a Zn(II)2Cys6 binuclear cluster.

1990 • 211 citations

Zinc transfer from transcription factor IIIA fingers to thionein clusters.

1991 • 204 citations

Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes.

1988 • 189 citations

Mapping functional regions of transcription factor TFIIIA.

1988 • 178 citations

Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene.

1988 • 147 citations

High-fidelity transcription of 5S DNA injected into Xenopus oocytes.

1977 • 146 citations

Zinc Fingers

1993 • 137 citations

Immediate-early RNA 2.9 and early RNA 2.6 of bovine herpesvirus 1 are 3' coterminal and encode a putative zinc finger transactivator protein

1992 • 137 citations

Structure of the DNA-binding domain of zinc GAL4

1992 • 127 citations

The ontogeny of expression of murine metallothionein: Comparison with the α-fetoprotein gene

1984 • 127 citations

[4] Nutritional and physiologic significance of metallothionein

1991 • 127 citations

Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae

1992 • 123 citations

Zinc finger proteins: what we know and what we would like to know

1991 • 121 citations

Toxicological Significance of Metallothionein

1987 • 118 citations

castor encodes a novel zinc finger protein required for the development of a subset of CNS neurons in drosophila

1992 • 117 citations

The cysteine-rich domain of human proteins, neuronal chimaerin, protein kinase C and diacylglycerol kinase binds zinc. Evidence for the involvement of a zinc-dependent structure in phorbol ester binding

1991 • 115 citations

Altered levels of a 5 S gene-specific transcription factor (TFIIIA) during oogenesis and embryonic development of Xenopus laevis.

1984 • 111 citations

Developmental regulation, induction, and embryonic tissue specificity of sea urchin metallothionein gene expression

1984 • 106 citations

Identification and zinc dependence of the bovine herpesvirus 1 transactivator protein BICP0

1994 • 95 citations

Immunohistochemical localization of metallothionein in developing rat tissues.

1989 • 88 citations

Zinc-binding protein in the livers of neonatal, normal and partially hepatectomized rats

1978 • 83 citations

High Levels of Metallothionein Messenger RNAs in Male Germ Cells of the Adult Mouse

1991 • 78 citations

A role of metallothionein in zinc regulation after oestradiol induction of vitellogenin synthesis in rainbow trout, Salmo gairdneri

1989 • 70 citations

Progesterone Induction of Metallothionein-II_AGene Expression

1988 • 60 citations

Heavy metal ions in transcription factors from HeLa cells: Sp1, but not octamer transcription factor requires zinc for DNA binding and for activator function

1988 • 57 citations

Investigation of zinc‐binding affinities of moloney murine leukemia virus nucleocapsid protein and its related zinc finger and modified peptides

1991 • 53 citations

Identification and characterization of "zinc-finger" domains by the polymerase chain reaction.

1991 • 47 citations

Zinc release from Xenopus transcription factor IIIA induced by chemical modifications

1989 • 46 citations

Role for zinc in a cellular response mediated by protein kinase C in human B lymphocytes

1991 • 29 citations

Isolation and characterization of complementary DNA clones corresponding to genes induced in mouse epidermis in vivo by tumor promoters.

1990 • 27 citations

Induction of metallothionein mRNA by tumor promoters in mouse skin and its constitutive expression in papillomas

1989 • 25 citations

Xenopus transcription factor IIIA (XTFIIIA): after a decade of research

1991 • 12 citations

A neurofilament-specific sequence motif

1992 • 9 citations