The GABAB Receptor Profile of a Series of Phosphinic Acids: Agonist and Antagonist Activity in a Range of Peripheral Tissues

(–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

1980 • 1,091 citations

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1981 • 1,044 citations

GABAB receptors and their significance in mammalian pharmacology

1989 • 400 citations

Characteristics of GABA_B receptor binding sites on rat whole brain synaptic membranes

1983 • 377 citations

Bicuculline-insensitive gaba receptors on peripheral autonomic nerve terminals

1981 • 376 citations

Phaclofen: a peripheral and central baclofen antagonist

1987 • 349 citations

Characteristics of GABA_B receptor binding sites on rat whole brain synaptic membranes

1997 • 294 citations

2-Hydroxy-saclofen: an improved antagonist at central and peripheral GABAB receptors

1988 • 202 citations

Baclofen: 10 years on

1982 • 201 citations

The postjunctional effects and neural release of purine compounds in the guinea-pig vas deferens

1978 • 187 citations

GABAA- and GABAB-receptor-mediated modification of intestinal motility

1982 • 170 citations

GABA_A and GABA_B receptor‐mediated effects in guinea‐pig ileum

1983 • 167 citations

Electrophysiological characterization of potent agonists and antagonists at pre‐ and postsynaptic GABA_B receptors on neurones in rat brain slices

1990 • 152 citations

GABAB receptors in mammalian function

1991 • 146 citations

PRESYNAPTIC γ‐AMINOBUTYRIC ACID RECEPTORS IN THE RAT ANOCOCCYGEUS MUSCLE AND THEIR ANTAGONISM BY 5‐AMINOVALERIC ACID

1982 • 122 citations

γ-Aminobutyric acid action in guinea-pig ileal myenteric plexus

1982 • 112 citations

Systemic baclofen stimulates gastric motility and secretion via a central action in the rat

1986 • 65 citations

Hypothermia induced by baclofen, a possible index of GABA_B receptor function in mice, is enhanced by antidepressant drugs and ECS

1987 • 64 citations

Synthesis and pharmacological evaluation of .gamma.-aminobutyric acid analogs. New ligand for GABAB sites

1987 • 54 citations

Antagonism at GABAB receptors by saclofen and related sulphonic analogues of baclofen and GABA

1989 • 53 citations

Modulatory activity of GABA_B receptors on cholinergic tone in guinea‐pig distal colon

1985 • 35 citations

Synthesis of γ-Aminopropylphosphonous Acids Using Hypophosphorous Acid Synthons

1987 • 31 citations

3‐Aminopropylphosphinic acid—a potent, selective GABA_B receptor agonist in the guinea‐pig ileum and rat anococcygeus muscle

1989 • 29 citations

Benzofuran analogues of baclofen: a new class of central and peripheral GABAB-receptor antagonists

1989 • 26 citations

Antagonism of GABA_B‐receptor‐mediated responses in the guinea‐pig isolated ileum and vas deferens by phosphono‐analogues of GABA

1990 • 22 citations

Evidence that antagonism by σ-aminovaleric acid of GABAB receptors in the guinea-pig ileum may be due to an interaction between GABAA and GABAB receptors

1986 • 19 citations

Injection of baclofen into the ventromedial hypothalamus stimulates gastric motility in the rat

1987 • 16 citations

5‐AMINOVALERIC ACID INTERACTIONS WITH GABA_A AND GABA_B RECEPTORS IN GUINEA‐PIG ILEUM

1985 • 16 citations

GABAB receptor antagonist and GABAA receptor agonist properties of a δ-aminovaleric acid derivative, Z-5-aminopent-2-enoic acid

1988 • 12 citations

Confirming Inexact Generalizations

1988 • 2 citations