Proteoglycans and Wound Repair

Angiogenic Factors

1987 • 3,702 citations

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

The Pathogenesis of Atherosclerosis

1976 • 2,000 citations

Cell Biology of Extracellular Matrix

1988 • 1,498 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Physiological function of connective tissue polysaccharides.

1978 • 995 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Glycosaminoglycans and Their Binding to Biological Macromolecules

1978 • 835 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Suppression by heparin of smooth muscle cell proliferation in injured arteries

1977 • 798 citations

Isolation of a heparan sulfate-containing proteoglycan from basement membrane.

1980 • 672 citations

Structure-activity relationship in heparin: A synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

1983 • 651 citations

The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.

1984 • 634 citations

Cell Adhesion Molecules in the Regulation of Animal Form and Tissue Pattern

1986 • 630 citations

Angiogenesis Inhibition and Tumor Regression Caused by Heparin or a Heparin Fragment in the Presence of Cortisone

1983 • 622 citations

Protamine is an inhibitor of angiogenesis

1982 • 582 citations

Interleukin 1: An Immunological Perspective

1985 • 576 citations

Cell-Surface Glycosaminoglycans

1984 • 552 citations

The fibronexus: a transmembrane association of fibronectin-containing fibers and bundles of 5 nm microfilaments in hamster and human fibroblasts

1979 • 536 citations

Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA.

1986 • 533 citations

Mechanism of the anticoagulant action of heparin

1982 • 486 citations

Structure and function of heparan sulphate proteoglycans

1986 • 485 citations

Proteoglycans in health and disease: structures and functions

1986 • 453 citations

Further characterization of the antithrombin-binding sequence in heparin

1982 • 450 citations

Mast cell heparin stimulates migration of capillary endothelial cells in vitro.

1980 • 445 citations

Dermatan sulphate-rich proteoglycan associates with rat tail-tendon collagen at the d band in the gap region

1981 • 440 citations

Glycosaminoglycans in Morphogenesis

1981 • 436 citations

Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.

1984 • 429 citations

Adhesion and cytoskeletal organisation of fibroblasts in response to fibronectin fragments.

1986 • 429 citations

Relationships between fibronectin (LETS protein) and actin

1978 • 428 citations

Native heparin from rat peritoneal mast cells.

1977 • 404 citations

Induction of fibroblast chemotaxis by fibronectin. Localization of the chemotactic region to a 140,000-molecular weight non-gelatin-binding fragment.

1981 • 372 citations

PROTEOGLYCAN CORE PROTEIN FAMILIES

1986 • 367 citations

A PATTERN OF EPIDERMAL CELL MIGRATION DURING WOUND HEALING

1971 • 365 citations

Structure of the antithrombin-binding site in heparin.

1979 • 362 citations

Hyaluronate production and removal during corneal development in the chick

1971 • 356 citations

Extension and structural variability of the antithrombin-binding sequence in heparin.

1984 • 340 citations

The extracellular matrix of the regenerating newt limb: Synthesis and removal of hyaluronate prior to differentiation

1971 • 329 citations

Migration of cranial neural crest cells in a cell-free hyaluronate-rich matrix

1975 • 317 citations

An antiproliferative heparan sulfate species produced by postconfluent smooth muscle cells.

1985 • 315 citations

Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro.

1984 • 314 citations

Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin. Possible role of a platelet endoglycosidase.

1982 • 312 citations

Inhibition of phagocytosis by high molecular weight hyaluronate.

1980 • 304 citations

The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans.

1985 • 301 citations

Binding and internalization of heparin by vascular smooth muscle cells

1985 • 298 citations

Fibronectin fragment(s) are chemotactic for human peripheral blood monocytes.

1982 • 292 citations

Basement membrane glycoprotein laminin binds to heparin

1980 • 286 citations

Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor.

1981 • 283 citations

Cell surface heparan sulfate mediates some adhesive responses to glycosaminoglycan-binding matrices, including fibronectin.

1983 • 281 citations

Effects of LETS glycoprotein on cell motility

1978 • 277 citations

Isolation of glycosaminoglycans (heparan sulfate) from glomerular basement membranes

1979 • 270 citations

Immunocytochemical localization of native chondroitin-sulfate in tissues and cultured cells using specific monoclonal antibody

1984 • 266 citations

In vivo co-distribution of fibronectin and actin fibers in granulation tissue: immunofluorescence and electron microscope studies of the fibronexus at the myofibroblast surface.

1984 • 261 citations

A unique heparan sulfate in the nuclei of hepatocytes: structural changes with the growth state of the cells.

1986 • 260 citations

Oligosaccharides on proteoglycans from the swarm rat chondrosarcoma.

1980 • 256 citations

Role of ternary complexes, in which heparin binds both antithrombin and proteinase, in the acceleration of the reactions between antithrombin and thrombin or factor Xa.

1986 • 254 citations

Anticoagulantly active heparin-like molecules from vascular tissue

1984 • 248 citations

Cell-surface heparan sulfate: an intercalated membrane proteoglycan.

1981 • 246 citations

Biosynthesis of heparin

1986 • 245 citations

The behaviour of fibroblasts migrating from chick heart explants: changes in adhesion, locomotion and growth, and in the distribution of actomyosin and fibronectin

1979 • 244 citations

Human apolipoprotein E. Determination of the heparin binding sites of apolipoprotein E3.

1986 • 242 citations

Involvement of phosphatidylinositol and insulin in the coordinate regulation of proteoheparan sulfate metabolism and hepatocyte growth.

1987 • 237 citations

Prevention of gastrulation but not neurulation by antibodies to fibronectin in amphibian embryos

1984 • 235 citations

Sulfated proteoglycans synthesized by vascular endothelial cells in culture.

1983 • 233 citations

Complexing of fibronectin glycosaminoglycans and collagen

1980 • 233 citations

Control of corneal differentiation by extracellular materials. Collagen as a promoter and stabilizer of epithelial stroma production

1974 • 225 citations

A heparin-binding domain from N-CAM is involved in neural cell-substratum adhesion.

1986 • 216 citations

Regulation of granulocyte function by hyaluronic acid. In vitro and in vivo effects on phagocytosis, locomotion, and metabolism.

1980 • 213 citations

A proteoglycan form of heparin and its degradation to single-chain molecules.

1978 • 211 citations

Inhibition of vascular smooth muscle cell migration by heparin‐like glycosaminoglycans

1984 • 207 citations

Fibronectin promotes epithelial migration of cultured rabbit cornea in situ.

1983 • 206 citations

Binding of hyaluronate to the surface of cultured cells.

1979 • 204 citations

Molecular cloning and sequence analysis of a chondroitin sulfate proteoglycan cDNA.

1985 • 202 citations

Neutralization of heparin-related saccharides by histidine-rich glycoprotein and platelet factor 4.

1986 • 200 citations

Contractile systems in non-muscle tissues

1977 • 193 citations

The Interaction of Heparin with an Apoprotein of Human Very Low Density Lipoprotein

1977 • 193 citations

Structural determinants of the capacity of heparin to inhibit the proliferation of vascular smooth muscle cells

1984 • 189 citations

The turnover of basal lamina glycosaminoglycan correlates with epithelial morphogenesis

1982 • 187 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.

1985 • 185 citations

Domain structure of vitronectin. Alignment of active sites.

1984 • 181 citations

Synthesis of hyaluronate in differentiated teratocarcinoma cells. Mechanism of chain growth

1983 • 178 citations

Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells.

1976 • 177 citations

The cell attachment domain of fibronectin. Determination of the primary structure.

1982 • 177 citations

Cell Migration in the Vertebrate Embryo: Role of Cell Adhesion and Tissue Environment in Pattern Formation

1985 • 174 citations

Fibronectin has a dual role in locomotion and anchorage of primary chick fibroblasts and can promote entry into the division cycle.

1982 • 168 citations

Binding of lipoprotein lipase to endothelial cells in culture.

1981 • 164 citations

Relationship of heparan sulfate proteoglycans to the cytoskeleton and extracellular matrix of cultured fibroblasts.

1984 • 162 citations

Structural determinants of the capacity of heparin to inhibit the proliferation of vascular smooth muscle cells. II. Evidence for a pentasaccharide sequence that contains a 3-O-sulfate group.

1986 • 162 citations

Morphology Of Delayed-Type Hypersensitivity Reactions In Man

1976 • 161 citations

Distribution and synthesis of glycosaminoglycans during quail neural crest morphogenesis

1978 • 156 citations

Chondroitin sulfate proteoglycan (PG-M-like proteoglycan) is involved in the binding of hyaluronic acid to cellular fibronectin.

1986 • 154 citations

Cell surface proteoglycan of mammary epithelial cells. Protease releases a heparan sulfate-rich ectodomain from a putative membrane-anchored domain.

1985 • 154 citations

Primordial germ cells of Xenopus embryos: The role of fibronectin in their adhesion during migration

1981 • 152 citations

Proteoglycans

1981 • 151 citations

Interaction of plasma lipoproteins containing apolipoproteins B and E with heparin and cell surface receptors

1979 • 150 citations

Structural analyses on the matrical organization of glycosaminoglycans in developing endocardial cushions

1978 • 148 citations

A unique family of endothelial cell polypeptide mitogens: the antigenic and receptor cross-reactivity of bovine endothelial cell growth factor, brain-derived acidic fibroblast growth factor, and eye-derived growth factor-II.

1985 • 146 citations

Effects of detergent solubilization on the hyaluronate-binding protein from membranes of simian virus 40-transformed 3T3 cells.

1983 • 141 citations

The Biosynthesis of Hyaluronic Acid by Streptococcus

1969 • 138 citations

Heparan sulfate proteoglycans of rat embryo fibroblasts. A hydrophobic form may link cytoskeleton and matrix components.

1985 • 138 citations

Relationship of transformation, cell density, and growth control to the cellular distribution of newly synthesized glycosaminoglycan.

1976 • 136 citations

Inhibition of leukocyte locomotion by hyaluronic acid

1981 • 134 citations

Cell surface changes correlated with density-dependent growth inhibition. Glycosaminoglycan metabolism in 3T3, SV3T3, and Con A selected revertant cells

1975 • 132 citations

Modulation of sulfated proteoglycan synthesis by bovine aortic endothelial cells during migration.

1986 • 131 citations

Biosynthesis of heparin. Concerted action of late polymer-modification reactions.

1980 • 130 citations

Cartilage proteoglycans inhibit fibronectin-mediated adhesion

1981 • 128 citations

Purification of a hyaluronate-binding protein fraction that modifies cell social behavior

1982 • 124 citations

The primary structure of link protein from rat chondrosarcoma proteoglycan aggregate.

1986 • 123 citations

The cell binding fragment of fibronectin is chemotactic for fibroblasts

1981 • 122 citations

Enhanced synthesis and extracellular accumulation of hyaluronic acid during stimulation of quiescent human fibroblasts by mouse epidermal growth factor

1976 • 120 citations

The inhibition of sulphate incorporation in isolated adult chondrocytes by hyaluronic acid

1973 • 116 citations

Inhibition of proteoglycan biosynthesis by hyaluronic acid in chondrocytes in cell culture

1976 • 116 citations

Depression by hyaluronic acid of glycosaminoglycan synthesis by cultured chick embryo chondrocytes

1974 • 115 citations

Identification of core protein, an intermediate in proteoglycan biosynthesis in cultured chondrocytes from the Swarm rat chondrosarcoma.

1981 • 115 citations

Synthesis of hyaluronate in differentiated teratocarcinoma cells. Characterization of the synthase

1983 • 115 citations

Evidence for an ionic binding of lipoprotein lipase to heparin

1971 • 111 citations

Characterization of platelet endoglycosidase degrading heparin-like polysaccharides

1980 • 111 citations

Glycosaminoglycans that bind cold-insoluble globulin in cell-substratum adhesion sites of murine fibroblasts.

1980 • 110 citations

Physical characteristics of hyaluronate binding to the surface of simian virus 40-transformed 3T3 cells.

1980 • 109 citations

Effect of a proteoglycan produced by rat tumor cells on their adhesion to fibronectin-collagen substrata.

1983 • 105 citations

Cloning and sequence analysis of a partial cDNA for chicken cartilage proteoglycan core protein.

1986 • 105 citations

Production of a heparin-binding angiogenesis factor by the embryonic kidney.

1986 • 105 citations

Glycosaminoglycan synthesis in rat embryos during the formation of the primary mesenchyme and neural folds

1977 • 102 citations

Remodelling of the Basement Membrane: Morphogenesis and Maturation

1984 • 101 citations

Isolation and characterization of the heparan sulfate proteoglycan of the bovine glomerular basement membrane.

1984 • 100 citations

Stimulation of Extracellular Matrix Synthesis in the Developing Cornea by Glycosaminoglycans

1974 • 99 citations

Binding of the basement-membrane glycoprotein laminin to glycosaminoglycans. An affinity-chromatography study

1981 • 99 citations

Cell adhesion and proteoglycans: I. the effect of exogenous proteoglycans on the attachment of chick embryo fibroblasts to tissue culture plastic and collagen

1979 • 97 citations

Structure and properties of an under-sulfated heparan sulfate proteoglycan synthesized by a rat hepatoma cell line.

1984 • 96 citations

Laminin, Proteoglycan, Nidogen and Collagen IV: Structural Models and Molecular Interactions

1984 • 95 citations

Fibronectin-Mediated Keratinocyte Migration and Initiation of Fibronectin Receptor Function In Vitro

1985 • 92 citations

Heparan sulfate proteoglycan of cultured cells: Demonstration of a lipid- and a matrix-associated form

1981 • 91 citations

Analysis of cell-growth-phase-related variations in hyaluronate synthase activity of isolated plasma-membrane fractions of cultured human skin fibroblasts

1986 • 91 citations

Translation and characterization of messenger RNAs in differentiating chicken cartilage.

1979 • 89 citations

Biosynthesis of hyaluronic acid by Streptococcus.

1979 • 88 citations

STRUCTURAL ALTERATION IN ISOLATED RAT LIVER NUCLEI AFTER REMOVAL OF TEMPLATE RESTRICTION BY POLYANIONS

1972 • 86 citations

Are glycoproteins and glycosaminoglycans components of the eukaryotic genome?

1975 • 83 citations

The interaction of natural and synthetic polyanions with mammalian nuclei

1970 • 83 citations

Guidance of myogenic cell migration by oriented deposits of fibronectin

1983 • 82 citations

The role of proteoglycan in the development of sea urchins

1979 • 81 citations

Effect of hyaluronic acid on neutrophil adhesion

1981 • 80 citations

The glycosaminoglycans of open wounds

1980 • 80 citations

Conditioning of native substrates by chondroitin sulfate proteoglycans during cardiac mesenchymal cell migration.

1986 • 79 citations

Glycosaminoglycans and glycoproteins associated with rat brain nuclei

1976 • 77 citations

Mucopolysaccharides associated with nuclei of cultured mammalian cells.

1975 • 75 citations

Hyaluronic acid synthetase in cultured mammalian cells producing hyaluronic acid Oscillatory change during the growth phase and suppression by 5-bromodeoxyuridine

1974 • 73 citations

Topographic localization of the heparin-binding domain of the neural cell adhesion molecule N-CAM.

1986 • 72 citations

Multiple classes of heparan sulfate proteoglycans from fibroblast substratum adhesion sites. Affinity fractionation on columns of platelet factor 4, plasma fibronectin, and octyl-sepharose.

1984 • 69 citations

Identification from cDNA of the precursor form of a chondroitin sulfate proteoglycan core protein.

1986 • 68 citations

Receptor-mediated endocytosis of proteoglycans by human fibroblasts involves recognition of the protein core

1983 • 63 citations

Self-association of heparan sulfate. Demonstration of binding by affinity chromatography of free chains on heparan sulfate-substituted agarose gels.

1981 • 63 citations

Heparan sulfate-chondroitin sulfate hybrid proteoglycan of the cell surface and basement membrane of mouse mammary epithelial cells.

1985 • 62 citations

Lactosaminoglycans and heparan sulfate are covalently bound to fibronectins synthesized by mouse stem teratocarcinoma cells.

1983 • 62 citations

Isolation and identification of glycosaminoglycans associated with purified nuclei from rat liver

1977 • 58 citations

Interactions of cartilage proteoglycans with hyaluronate. Inhibition of the interaction by modified oligomers of hyaluronate.

1979 • 58 citations

Specific association of iduronic acid-rich dermatan sulphate with the extracellular matrix of human skin fibroblasts cultured on collagen gels

1983 • 58 citations

Characterization of a high-Mr plasma-membrane-bound protein and assessment of its role as a constituent of hyaluronate synthase complex

1986 • 57 citations

Increased hyaluronic acid production on stimulation of DNA synthesis in chick embryo fibroblasts

1975 • 56 citations

Specific interaction between cartilage proteoglycans and hyaluronic acid at the chondrocyte cell surface

1983 • 55 citations

Liver plasma membranes and proteoglycan prepared therefrom inhibit the growth of hepatoma cells in vitro

1981 • 54 citations

Self-association of scleral proteodermatan sulfate. Evidence for interaction via the dermatan sulfate side chains.

1982 • 51 citations

Isolation and characterization of proteoheparan sulfate synthesized in vitro by rat glomeruli.

1983 • 49 citations

An amino acid sequence common to both cartilage proteoglycan and link protein.

1985 • 46 citations

Inhibition of cell migration in sea urchin embryos by β-d-xyloside

1986 • 45 citations

Influences of anionic polysaccharides on DNA synthesis in isolated nuclei and by DNA polymerase α: Correlation of observed effects with properties of the polysaccharides

1983 • 45 citations

Mucopolysaccharides, Collagen, and Nonfibrillar Proteins in Inflammation

1964 • 44 citations

Fluorescent morphological probe for hyaluronate.

1985 • 43 citations

Chondroitin sulfate at the plasma membranes of cultured fibroblasts.

1983 • 43 citations

Visualization of heparin-binding proteins by ligand blotting with 125I-heparin

1984 • 42 citations

Location of a fibronectin domain involved in newt epidermal cell migration.

1985 • 42 citations

AN INTEGRAL MEMBRANE PROTEOGLYCAN IS CAPABLE OF BINDING COMPONENTS OF THE CYTOSKELETON AND THE EXTRACELLULAR MATRIX11This work was supported by NIH grants CA28735 and HD06763 and NIH training grant GM07781.

1982 • 40 citations

Solubilization of hyaluronic acid synthetic activity from streptococci and its activation with phospholipids.

1986 • 40 citations

Biosynthesis of heparin. Concerted action of early polymer-modification reactions.

1982 • 40 citations

Streptococcal hyaluronic acid: proposed mechanisms of degradation and loss of synthesis during stationary phase

1983 • 39 citations

Hyaluronate-protein complex of rous sarcoma virus-transformed chick embryo fibroblasts.

1981 • 36 citations

Cell-free synthesis of cartilage proteins: partial identification of proteoglycan core and link proteins

1980 • 36 citations

Localization of sulfated glycosaminoglycans within cell nuclei by high-resolution autoradiography

1976 • 30 citations

Pattern of glycosaminoglycans and glycoproteins associated with nuclei of regenerating liver of rat

1979 • 30 citations

Glycosaminoglycans and other carbohydrate groups bound to proteins of control and transformed cells.

1980 • 28 citations

Common Structures of the Core Proteins of Interstitial Proteoglycans

2007 • 28 citations

Isolation of lipid glucuronic acid and N-acetylglucosamine derivatives from a rat fibrosarcoma

1977 • 25 citations

Proteoglycan Biosynthesis

1981 • 24 citations

Introduction

1975 • 15 citations

Glycosaminoglycan Changes in Healing Myocardial Infarction

1978 • 11 citations

The Allure of High-Tech Weapons for Europe

1984 • 4 citations

The effect of strychnin in cardiectomized frogs with destroyed lymph hearts; a demonstration

1912 • 4 citations

The Effect of Hyaluronic Acid on Neutrophil Function in Vitro and in Vivo

1982 • 2 citations

Deleted Work

1955 • 0 citations