Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Current protocols in molecular biology

1988 • 4,543 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH.

1984 • 544 citations

Effects of Growth Factors on Intracellular pH Regulation

1986 • 498 citations

A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells

1985 • 456 citations

Avian leukemia viruses interaction with their target cells in vivo and in vitro

1978 • 421 citations

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1989 • 387 citations

Developmental regulation of β-globin gene switching

1988 • 328 citations

Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes

1983 • 296 citations

Activation of the cellular oncogene c-erbB by ltr insertion: Molecular basis for induction of erythroblastosis by avian leukosis virus

1983 • 289 citations

Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene

1982 • 242 citations

v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA

1990 • 236 citations

Hormone-dependent terminal differentiation in vitro of chicken erythroleukemia cells transformed by ts mutants of avian erythroblastosis virus

1982 • 220 citations

c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor

1985 • 216 citations

Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro

1982 • 188 citations

Role of the v-erbA and v-erbB oncogenes of avian erythroblastosis virus in erythroid cell transformation

1983 • 188 citations

Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells

1980 • 184 citations

Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential binding of EGF and transforming growth factor alpha.

1988 • 178 citations

Temperature-sensitive mutant of avian erythroblastosis virus suggests a block of differentiation as mechanism of leukaemogenesis

1978 • 173 citations

v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation

1986 • 156 citations

v-erbA specifically suppresses transcription of the avian erythrocyte anion transporter (Band 3) gene

1988 • 153 citations

A new avian erythroblastosis virus, AEV-H, carries erbB gene responsible for the induction of both erythroblastosis and sarcomas

1983 • 137 citations

Activation of protein kinase C or cAMP-dependent protein kinase increases phosphorylation of the c-erbA-encoded thyroid hormone receptor and of the v-erbA-encoded protein.

1988 • 136 citations

Two types of target cells for transformation with avian myelocytomatosis virus

1973 • 128 citations

Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity

1983 • 127 citations

Characterization of the hormone-binding domain of the chicken c-erbA/thyroid hormone receptor protein.

1988 • 109 citations

Temperature-sensitive mutants of avian erythroblastosis virus: Surface expression of the erbB product correlates with transformation

1984 • 98 citations

Target cells infected by avian erythroblastosis virus differentiate and become transformed

1982 • 96 citations

A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes.

1987 • 87 citations

High-frequency transduction of c-erbB in avian leukosis virus-induced erythroblastosis

1985 • 84 citations

v-erbA overexpression is required to extinguish c-erbA function in erythroid cell differentiation and regulation of the erbA target gene CAII.

1991 • 83 citations

Phosphorylation of the v-erbA protein is required for its function as an oncogene.

1990 • 83 citations

EGF-R as a hemopoietic growth factor receptor: The c-erbB product is present in chicken erythrocytic progenitors and controls their self-renewal

1991 • 80 citations

src- and fps-containing avian sarcoma viruses transform chicken erythroid cells.

1984 • 76 citations

Expression of the v-erbA product, an altered nuclear hormone receptor, is sufficient to transform erythrocytic cells in vitro

1989 • 73 citations

Avian erythroblastosis virus produces two mRNA's

1980 • 60 citations

Chicken Epidermal Growth Factor (EGF) Receptor: cDNA Cloning, Expression in Mouse Cells, and Differential Binding of EGF and Transforming Growth Factor Alpha

1988 • 50 citations

The avian erythroblastosis virus erbA oncogene encodes a DNA-binding protein exhibiting distinct nuclear and cytoplasmic subcellular localizations

1988 • 47 citations

Modern Trends in Human Leukemia VI

1987 • 47 citations

The chicken carbonic anhydrase II gene: evidence for a recent shift in intron position

1987 • 45 citations

Temperature-sensitive v-sea transformed erythroblasts: a model system to study gene expression during erythroid differentiation.

1988 • 45 citations

A single amino acid substitution in v-erbB confers a thermolabile phenotype to ts167 avian erythroblastosis virus-transformed erythroid cells.

1986 • 43 citations

Avian Erythroblastosis Virus Isolated From Chick Erythroblastosis Induced by Lymphatic Leukemia Virus Subgroup A<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref><xref ref-type="fn" rid="FN4">4</xref>

1983 • 40 citations

Oncornavirus-induced sarcoma formation obscured by rapid development of lethal leukemia.

1977 • 36 citations

The lack of transcriptional activation of the v-erbA oncogene is in part due to a mutation present in the DNA binding domain of the protein

1990 • 35 citations

Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector

1990 • 35 citations

Ontogeny of the v-erbA oncoprotein from the thyroid hormone receptor: an alteration in the DNA binding domain plays a role crucial for v-erbA function

1991 • 34 citations

The carbonic anhydrase II gene, a gene regulated by thyroid hormone and erythropoietin, is repressed by the v-erbA oncogene in erythrocytic cells.

1990 • 31 citations

Genetic dissection of functional domains within the avian erythroblastosis virus v-erbA oncogene.

1988 • 28 citations

Changes in the Expression of Membrane Antigens During the Differentiation of Chicken Erythroblasts

1982 • 24 citations

Requirement for the C-terminal domain of the v-erbA oncogene protein for biological function and transcriptional repression.

1990 • 24 citations

The v-erb A oncogene causes repression of erythrocyte-specific genes and an immature, aberrant differentiation phenotype in normal erythroid progenitors.

1990 • 23 citations

A Single Amino Acid Substitution in v-erbB Confers a Thermolabile Phenotype to ts167 Avian Erythroblastosis Virus-Transformed Erythroid Cells

1986 • 18 citations

The nuclear oncogenes v-erbA and v-ets cooperate in the induction of avian erythroleukemia.

1992 • 13 citations

Common site of mutation in the erbB gene of avian erythroblastosis virus mutants that are temperature sensitive for transformation.

1987 • 9 citations

Genetic Dissection of Functional Domains within the Avian Erythroblastosis Virus v-erbA Oncogene

1988 • 5 citations