A Single Amino Acid Substitution in v-erbB Confers a Thermolabile Phenotype to ts167 Avian Erythroblastosis Virus-Transformed Erythroid Cells

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Fundamental techniques in virology.

1969 • 1,768 citations

A simple method for DNA restriction site mapping

1976 • 1,025 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

Autophosphorylation sites on the epidermal growth factor receptor

1984 • 730 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase

1980 • 378 citations

The erbB gene of avian erythroblastosis virus is a member of the src gene family

1983 • 377 citations

Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus

1982 • 318 citations

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbb protein

1985 • 310 citations

Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes

1983 • 296 citations

Isolation of the chicken β-globin gene and a linked embryonic β-like globin gene from a chicken DNA recombinant library

1979 • 243 citations

Hormone-dependent terminal differentiation in vitro of chicken erythroleukemia cells transformed by ts mutants of avian erythroblastosis virus

1982 • 220 citations

Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: A model system to study erythroid differentiation in vitro

1982 • 188 citations

Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells

1980 • 184 citations

Temperature-sensitive mutant of avian erythroblastosis virus suggests a block of differentiation as mechanism of leukaemogenesis

1978 • 173 citations

Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein

1983 • 167 citations

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro

1985 • 160 citations

Defectiveness of avian erythroblastosis virus: synthesis of a 75K gag-related protein

1979 • 158 citations

Evidence for the multiple oncogenic potential of cloned leukemia virus: In vitro and in vivo studies with avian erythroblastosis virus

1976 • 151 citations

A new avian erythroblastosis virus, AEV-H, carries erbB gene responsible for the induction of both erythroblastosis and sarcomas

1983 • 137 citations

Two types of target cells for transformation with avian myelocytomatosis virus

1973 • 128 citations

Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity

1983 • 127 citations

The product of the avian erythroblastosis virus erbB locus is a glycoprotein

1983 • 111 citations

Characterization of the hematopoietic target cells of AEV, MC29 and AMV avian leukemia viruses

1981 • 100 citations

Temperature-sensitive mutants of avian erythroblastosis virus: Surface expression of the erbB product correlates with transformation

1984 • 98 citations

Identification of a form of the avian erythroblastosis virus erb-B gene product at the cell surface

1984 • 86 citations

Virus-specific RNAs in cells infected by avian myelocytomatosis virus and avian erythroblastosis virus: Modes of oncogene expression

1981 • 71 citations

The membrane glycoprotein encoded by the retroviral oncogene v-erb-B is structurally related to tyrosine-specific protein kinases.

1984 • 67 citations

Avian erythroblastosis virus produces two mRNA's

1980 • 60 citations

Site-specific mutagenesis of avian erythroblastosis virus: v-erb-A is not required for transformation of fibroblasts

1983 • 56 citations

Analysis of the adult and embryonic chicken globin genes in chromosomal DNA.

1978 • 55 citations

Effects of inhibitors of glycoprotein processing on the synthesis and biological activity of the erb B oncogene.

1985 • 46 citations

Isolation and characterization of four new temperature-sensitive mutants of avian erythroblastosis virus (AEV)

1982 • 45 citations

Proteins specified by avian erythroblastosis virus: coding region localization and identification of a previously undetected erb-B polypeptide.

1982 • 41 citations