ATP citrate-lyase and glycogen synthase kinase-3β in 3T3-L1 cells during differentiation into adipocytes

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

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Molecular cloning and expression of glycogen synthase kinase-3/factor A.

1990 • 1,329 citations

Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase.

1980 • 896 citations

Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth-factor signalling

1993 • 877 citations

Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells

1976 • 826 citations

After Insulin Binds

1987 • 687 citations

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells.

1978 • 678 citations

Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.

1993 • 616 citations

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1990 • 529 citations

Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes.

1988 • 506 citations

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B

1993 • 399 citations

Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase.

1977 • 328 citations

Induction of lipogenesis during differentiation in a "preadipocyte" cell line.

1976 • 317 citations

Molecular Basis of Insulin Action

1985 • 309 citations

Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase.

1980 • 279 citations

Multisite phosphorylation of glycogen synthase

1984 • 208 citations

Molecular basis of insulin action

1986 • 201 citations

Synthesis and degradation of the lipogenic enzymes of rat liver

1972 • 186 citations

Regulation of fatty acid synthesis via phosphorylation of acetyl-CoA carboxylase

1989 • 186 citations

Effect of (−)‐hydroxycitrate upon the accumulation of lipid in the rat: I. Lipogenesis

1974 • 140 citations

Effects of epinephrine and insulin on phosphopeptide metabolism in adipocytes.

1976 • 133 citations

Rat ATP citrate-lyase. Molecular cloning and sequence analysis of a full-length cDNA and mRNA abundance as a function of diet, organ, and age.

1990 • 128 citations

Purification of a Hepatic S6 Kinase from Cycloheximide-treated Rats

1989 • 127 citations

Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport or glycogen synthase in 3T3-L1 adipocytes.

1993 • 119 citations

Purification and characterisation of the insulin‐stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II

1991 • 117 citations

Identification of multifunctional ATP-citrate lyase kinase as the α-isoform of glycogen synthase kinase-3

1992 • 113 citations

Role of pyruvate carboxylase in fatty acid synthesis: Alterations during preadipocyte differentiation

1977 • 107 citations

Actions of insulin, epinephrine, and dibutyryl adenosine cyclic 5'-monophosphate on fat cell protein phosphorylations. Adenosine cyclic 5'-monophosphate dependent and independent mechanisms

1975 • 105 citations

Protein phosphorylation

1982 • 104 citations

Insulin stimulates the dephosphorylation and activation of acetyl-CoA carboxylase.

1988 • 104 citations

Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. I. Multiple hormone regulatory elements and the effects of enhancers.

1986 • 103 citations

Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast‐atom‐bombardment mass spectrometry

1988 • 101 citations

Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6.

1980 • 98 citations

Phosphoserine as a recognition determinant for glycogen synthase kinase-3: Phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1

1988 • 95 citations

Gene expression during 3T3-L1 adipocyte differentiation. Characterization of initial responses to the inducing agents and changes during commitment to differentiation.

1992 • 82 citations

ATP-citrate lyase. Structure of a tryptic peptide containing the phosphorylation site directed by glucagon and the cAMP-dependent protein kinase.

1981 • 79 citations

Early events in insulin actions.

1986 • 74 citations

Fat cell protein phosphorylation. Identification of phosphoprotein-2 as ATP-citrate lyase.

1979 • 71 citations

Structure of ATP citrate lyase from rat liver. Physicochemical studies and proteolytic modification.

1976 • 70 citations

Sequence of sites on ATP-citrate lyase and phosphatase inhibitor 2 phosphorylated by multifunctional protein kinase (a glycogen synthase kinase 3 like kinase)

1990 • 65 citations

Signal Transduction and Protein Phosphorylation in the Regulation of Cellular Metabolism by Insulin

1992 • 61 citations

Effect of insulin on the phosphorylation of adipose tissue protein

1974 • 53 citations

Insulin action rapidly decreases multifunctional protein kinase activity in rat adipose tissue.

1988 • 45 citations

Hormonal regulation of the phosphorylation of ATP citrate lyase in 3T3-L1 adipocytes. Effects of insulin and isoproterenol.

1982 • 41 citations

Phosphorylation of ATP-citrate lyase by a cyclic AMP-independent protein kinase from a rat liver

1981 • 37 citations

Hormonal control of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression in rat hepatoma cells

1991 • 36 citations

Regulation of ATP-citrate lyase in primary cultures of adult rat hepatocytes.

1979 • 34 citations

Cyclic nucleotide-independent protein kinase from rat liver. Purification and characterization of a multifunctional protein kinase.

1985 • 30 citations

Dependence of ATP-citrate lyase kinase activity on the phosphorylation of ATP-citrate lyase by cyclic AMP-dependent protein kinase.

1983 • 29 citations

Effect of insulin on ATP-citrate lyase phosphorylation: regulation of peptide A and peptide B phosphorylations

1989 • 22 citations

Insulin stimulates phosphorylation of a heat-stable protein in rat adipose tissue

1983 • 14 citations

An insulin-sensitive cytosolic protein kinase accounts for the regulation of ATP citrate-lyase phosphorylation

1990 • 14 citations

Insulin stimulates the dephosphorylation of phosphothreonine from FAT-PAD ATP-citrate lyase

1984 • 12 citations

Phosphorylation of different sites of acetyl CoA carboxylase by ATP-citrate lyase kinase and cyclic AMP-dependent protein kinase

1983 • 11 citations

Rapid Purification of Enzymes of Fatty Acid Biosynthesis from Rat Adipose Tissue

1983 • 7 citations