[14] In vitro and in vivo systems to assess role of CXC chemokines in regulation of angiogenesis

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1970 • 253,849 citations

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Angiogenic Factors

1987 • 3,702 citations

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1994 • 3,367 citations

Requirement of Vascular Integrin α _v β ₃ for Angiogenesis

1994 • 3,016 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

1994 • 2,293 citations

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

1992 • 2,130 citations

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

1989 • 1,993 citations

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1996 • 1,973 citations

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1989 • 1,912 citations

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1991 • 1,864 citations

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1996 • 1,678 citations

Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.

1993 • 1,646 citations

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

1996 • 1,482 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis

1995 • 1,222 citations

Macrophages and angiogenesis

1994 • 1,123 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

Tumor Angiogenesis

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Regulators of Angiogenesis

1991 • 959 citations

Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix.

1989 • 877 citations

Activated macrophages induce vascular proliferation

1977 • 818 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Relation of neovascularisation to metastasis of non-small-cell lung cancer

1992 • 780 citations

Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines.

1992 • 737 citations

Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins

1993 • 722 citations

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

1990 • 710 citations

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo.

1995 • 710 citations

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

1990 • 678 citations

Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: partial characterization and separation from interleukin 1 (IL 1).

1987 • 613 citations

Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF

1989 • 602 citations

Protamine is an inhibitor of angiogenesis

1982 • 582 citations

Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

1993 • 574 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

The pericyte—A review

1986 • 563 citations

Inflammation: Basic Principles and Clinical Correlates

1993 • 518 citations

Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells.

1994 • 504 citations

A New Class of Steroids Inhibits Angiogenesis in the Presence of Heparin or a Heparin Fragment

1985 • 492 citations

Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses.

1987 • 491 citations

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene

1989 • 475 citations

The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation.

1995 • 456 citations

Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.

1991 • 437 citations

Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice.

1996 • 405 citations

Interleukin-8. A corneal factor that induces neovascularization.

1992 • 385 citations

Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.

1994 • 373 citations

Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding.

1991 • 372 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

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1984 • 366 citations

Inhibition of tumor angiogenesis mediated by cartilage.

1975 • 361 citations

Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases.

1996 • 358 citations

Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology to interleukin 8.

1991 • 349 citations

Mechanisms of neovascularization. Vascular sprouting can occur without proliferation of endothelial cells.

1984 • 339 citations

Macrophage-derived angiogenesis factors

1991 • 325 citations

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1974 • 294 citations

Cell turnover of capillaries.

1967 • 294 citations

Interferon γ-Inducible Protein-10 (IP-10), a Member of the C-X-C Chemokine Family, Is an Inhibitor of Angiogenesis

1995 • 293 citations

The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin.

1987 • 274 citations

Monokine-induced Neutrophil Chemotactic Factor Gene Expression in Human Fibroblasts

1989 • 272 citations

Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis.

1994 • 267 citations

Cytokine-induced neutrophil-derived interleukin-8.

1992 • 260 citations

Tumor-related angiogenesis

1989 • 256 citations

Extracellular matrix and cell shape: Potential control points for inhibition of angiogenesis

1991 • 247 citations

Neutrophil chemotactic factor (IL-8) gene expression by cytokine-treated retinal pigment epithelial cells.

1990 • 237 citations

Biology of tumor progression in human melanocytes.

1987 • 236 citations

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1990 • 211 citations

A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis

1993 • 211 citations

Human Alveolar Macrophage Gene Expression of Interleukin-8 by Tumor Necrosis Factor-α, Lipopolysaccharide, and Interleukin-1β

1990 • 208 citations

DEVELOPMENT OF THE VASCULAR SYSTEM

1983 • 207 citations

Shark Cartilage Contains Inhibitors of Tumor Angiogenesis

1983 • 204 citations

Endothelial cell gene expression in response to injury

1993 • 194 citations

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1993 • 194 citations

The formation of capillary basement membranes during internal vascularization of the rat's cerebral cortex

1972 • 193 citations

Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.

1994 • 190 citations

Growth Inhibition of Murine Melanoma and Human Colon Carcinoma by Recombinant Human Platelet Factor 4

1990 • 190 citations

Pathobiology of the Endothelial Cell

1982 • 190 citations

HuMig: A New Human Member of the Chemokine Family of Cytokines

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Interleukln-8 stimulates angiogenesis in rats

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1972 • 174 citations

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1988 • 169 citations

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1990 • 162 citations

The resistance of certain tissues to invasion. III. Cartilage extracts inhibit the growth of fibroblasts and endothelial cells in culture.

1975 • 157 citations

Pulmonary Fibroblast Expression of Interleukin-8: A Model for Alveolar Macrophage-derived Cytokine Networking

1991 • 153 citations

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1995 • 149 citations

Initiation and pattern of angiogenesis in wound healing in the rat

1991 • 145 citations

The sequence of events in the regression of corneal capillaries.

1978 • 141 citations

Stimulation of neovascularization by human rheumatoid synovial tissue macrophages

1986 • 137 citations

Development of the Vascular System

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1977 • 132 citations

The resistance of certain tissues to invasion. II. Evidence for extractable factors in cartilage which inhibit invasion by vascularized mesenchyme.

1975 • 130 citations

Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.

1992 • 129 citations

Regulation of Endothelial Cell Growth, Architecture, and Matrix Synthesis by TGF-β

1989 • 116 citations

Human neutrophils exhibit disparate chemotactic factor gene expression

1990 • 114 citations

Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis

1976 • 112 citations

Monokine-induced gene expression of a human endothelial cell-derived neutrophil chemotactic factor

1988 • 112 citations

Interferon-α and interferon-γ down-regulate the production of interleukin-8 and ENA-78 in human monocytes

1995 • 105 citations

Inhibitors of Angiogenesis

1991 • 102 citations

Distribution of Integrin Cell Adhesion Receptors on Normal Bronchial Epithelial Cells and Lung Cancer Cells In Vitro and In Vivo

1993 • 92 citations

Cytokine-activated human mesangial cells generate the neutrophil chemoattractant, interleukin 8

1991 • 89 citations

IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes.

1993 • 88 citations

Vitreous: an inhibitor of retinal extract-induced neovascularization.

1983 • 78 citations

Acquisition of angiogenic capacity and neoplastic transformation in the rat mammary gland.

1978 • 64 citations

Inhibition of basement membrane biosynthesis prevents angiogenesis.

1988 • 61 citations

Heparin-binding fragments of fibronectin are potent inhibitors of endothelial cell growth: structure-function correlations

1986 • 53 citations

Tumor angiogenesis inhibition by prostaglandin synthetase inhibitors.

1986 • 53 citations

Tumor necrosis factor inhibiting angiogenesis in vitro.

1987 • 53 citations

Comparison of gene expression in bovine aortic endothelium in vivo versus in vitro. Differences in growth regulatory molecules.

1993 • 52 citations

Inhibition of angiogenesis by the antineoplastic agents mitoxantrone and bisantrene

1986 • 41 citations

Efficacy of antitumor chemotherapy in C3H mice enhanced by the antiangiogenesis steroid, cortisone acetate.

1987 • 31 citations