Alterations of tubulin function caused by chronic antidepressant treatment in rat brain.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

1965 • 3,421 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

The Biochemistry of Affective Disorders

1967 • 1,183 citations

A rapid method for the regional dissection of the rat brain

1980 • 540 citations

Adenylate cyclase assay.

1979 • 485 citations

Tubulin binds specifically to the signal-transducing proteins, Gs alpha and Gi alpha 1.

1990 • 204 citations

Guanosine Triphosphate Activation of Brain Adenylate Cyclase: Enhancement by Long-Term Antidepressant Treatment

1983 • 142 citations

Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victims

1994 • 136 citations

Chronic Electroconvulsive Treatment Augments Coupling of the GTP‐Binding Protein G_s to the Catalytic Moiety of Adenylyl Cyclase in a Manner Similar to That Seen with Chronic Antidepressant Drugs

1991 • 110 citations

G protein binding and G protein activation by nucleotide transfer involve distinct domains on tubulin: Regulation of signal transduction by cytoskeletal elements

1993 • 97 citations

Coupling of the stimulatory GTP-binding protein Gs to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment.

1989 • 81 citations

Use of a GTP photoaffinity probe to resolve aspects of the mechanism of tubulin polymerization.

1979 • 80 citations

Chronic antidepressant treatment facilitates G protein activation of adenylyl cyclase without altering G protein content.

1995 • 78 citations

Exchange of Guanine Nucleotides Between Tubulin and GTP‐Binding Proteins That Regulate Adenylate Cyclase: Cytoskeletal Modification of Neuronal Signal Transduction

1988 • 76 citations

Chronic Treatment of C6 Glioma Cells with Antidepressant Drugs Increases Functional Coupling Between a G Protein (G_S) and Adenylyl Cyclase

1995 • 70 citations

Exchange of guanine nucleotide between GTP-binding proteins that regulate neuronal adenylate cyclase.

1986 • 47 citations

Depression and antidepressant therapy: Receptor dynamics

1990 • 43 citations

Divalent cation regulation of adenylyl cyclase. An allosteric site on the catalytic component.

1982 • 43 citations

Stoichiometry for guanine nucleotide binding to tubulin under polymerizing and nonpolymerizing conditions

1980 • 41 citations

Antidepressant treatments and regulation of norepinephrine-receptor-coupled adenylate cyclase systems in brain.

1984 • 37 citations

Electroconvulsive Shock and Cyclic AMP Signal Transduction: Effects Distal to the Receptor

1986 • 33 citations

Signal transduction modulation by lithium: cell culture, cerebral microdialysis and human studies.

1991 • 33 citations

Selective adenylate cyclase increase in the limbic area of long-term imipramine-treated rats

1990 • 27 citations

Participation of Tubulin in the Stimulatory Regulation of Adenylyl Cyclase in Rat Cerebral Cortex Membranes

1995 • 20 citations

Alteration of Tubulin‐G_i Protein Interaction in Rat Cerebral Cortex with Aging

1994 • 8 citations

[Effects of tubulin on beta adrenergic receptor linked to adenylyl cyclase system].

1993 • 2 citations