Increased intestinal protein synthesis during sepsis and following the administration of tumour necrosis factor α or interleukin-1 α

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Mammalian Protein Metabolism

1969 • 1,828 citations

Interleukin-1

1984 • 1,625 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. A comparison of germ-free and conventional mice.

1963 • 480 citations

Muscle Proteolysis Induced by a Circulating Peptide in Patients with Sepsis or Trauma

1983 • 469 citations

Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease.

1989 • 430 citations

Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro.

1986 • 398 citations

The effect of starvation on the rate of protein synthesis in rat liver and small intestine

1979 • 391 citations

Infusion of tumor necrosis factor/cachectin promotes muscle catabolism in the rat. A synergistic effect with interleukin 1.

1989 • 378 citations

The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans.

1990 • 372 citations

Effect of sepsis on tissue adenine nucleotide levels.

1979 • 329 citations

A new chromogenic endotoxin-specific assay using recombined limulus coagulation enzymes and its clinical applications

1985 • 286 citations

The biologic characteristics of cytokines and their implication in surgical injury.

1990 • 252 citations

Isolation and metabolic characteristics of rat and chicken enterocytes

1979 • 247 citations

The effects of endotoxaemia on protein metabolism in skeletal muscle and liver of fed and fasted rats

1986 • 203 citations

Current Concepts of Protein Turnover and Amino Acid Transport in Liver and Skeletal Muscle During Sepsis

1988 • 124 citations

Protein Metabolism in Different Types of Skeletal Muscle During Early and Late Sepsis in Rats

1986 • 114 citations

Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue.

1988 • 111 citations

Protein synthesis in liver and small intestine in protein deprivation and diabetes

1981 • 85 citations

Interaction between corticosterone and tumor necrosis factor stimulated protein breakdown in rat skeletal muscle, similar to sepsis.

1990 • 78 citations

Accelerated Lung Amino Acid Release in Hyperdynamic Septic Surgical Patients

1990 • 78 citations

Cachectin/TNF Production in Experimental Burns and Pseudomonas Infection

1988 • 76 citations

Differences in intestinal protein synthesis and cellular proliferation in well-nourished rats consuming conventional laboratory diets

1985 • 69 citations

Regulation of Small Intestinal Protein Metabolism

1973 • 65 citations

Are the Catabolic Effects of Tumor Necrosis Factor Mediated by Glucocorticoids?

1990 • 63 citations

Cytokines and glucocorticoids in the regulation of the “hepato-skeletal muscle axis” in sepsis

1991 • 59 citations

Measurement of protein synthesis in human skeletal muscle: further investigation of the flooding technique

1991 • 58 citations

Regulation of IL-1 and TNF-alpha expression during the differentiation of bone marrow derived macrophage.

1989 • 55 citations

Hemodynamic and metabolic alterations during experimental sepsis in young and adult rats.

1989 • 52 citations

Intestinal cellular proliferation and protein synthesis in zinc-deficient rats

1985 • 49 citations

Rapid method for micro-analysis of endogenous amino acid neurotransmitters in brain perfusates in the rat by isocratic HPLC-EC

1986 • 36 citations

Effect of sepsis or cytokine administration on release of gut peptides

1992 • 34 citations

Intestinal protein synthesis in guinea pigs infected with Trichostrongylus colubriformis

1983 • 34 citations

Protein loss and cell loss from the small-intestinal mucosa

1971 • 30 citations

Measurement of hepatic protein synthesis in unrestrained mice‐evaluation of the ‘flooding technique’

1991 • 25 citations

Antigen Presentation by Gut Epithelial Cells: Secretion by Rat Enterocytes of a Factor with IL-1-Like Activity

1987 • 24 citations

Effect of Diet Type on Enhanced Intestinal Protein Synthesis by the Gut Microflora in the Chick

1988 • 22 citations

Additive effects of thermal injury and infection on the small bowel.

1990 • 14 citations

Interleukin-1 Induces Mucus Secretion from Mouse Intestinal Explants

1987 • 14 citations

An increase in vasoactive intestinal peptide levels in canine endotoxin shock.

1981 • 13 citations

Release of vasoactive intestinal peptide during hyperdynamic sepsis in dogs.

1988 • 9 citations

Protein synthesis and secretion by hamster, rat and mouse jejunum

1984 • 8 citations