Ganglioside GM2 N-acetyl-beta-D-galactosaminidase activity in cultured fibroblasts of late-infantile and adult GM2 gangliosidosis patients and of healthy probands with low hexosaminidase level.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Quantitive estimation of sialic acids

1957 • 2,782 citations

Tay-Sachs Disease: Generalized Absence of a Beta-D- N -Acetylhexosaminidase Component

1969 • 707 citations

Deficient hexosaminidase activity in an exceptional case of Tay-Sachs disease with additional storage of kidney globoside in visceral organs

1968 • 329 citations

ENZYME ALTERATIONS AND LIPID STORAGE IN THREE VARIANTS OF TAY‐SACHS DISEASE

1971 • 292 citations

AB variant of infantile GM2 gangliosidosis: deficiency of a factor necessary for stimulation of hexosaminidase A-catalyzed degradation of ganglioside GM2 and glycolipid GA2.

1978 • 274 citations

Variation of β‐N‐acetylhexosaminidase‐pattern in Tay‐Sachs disease

1969 • 258 citations

Specific radioactive labeling of terminal N-acetylgalactosamine of glycosphingolipids by the galactose oxidase–sodium borohydride method

1972 • 207 citations

Purification and Characterization of an Activator Protein for the Degradation of Glycolipids G_M2and G_A2by Hexosaminidase A

1979 • 180 citations

An activator stimulating the enzymic hydrolysis of sphingoglycolipids.

1976 • 159 citations

Complexing of Glycolipids and Their Transfer between Membranes by the Activator Protein for Degradation of Lysosomal Ganglioside G_M2

1982 • 152 citations

The Activator of Cerebroside Sulphatase. Purification from Human Liver and Identification as a Protein

1975 • 135 citations

Chemical characterization and subunit structure of human N-acetylhexosaminidases A and B

1976 • 128 citations

Hexosaminidase-A and Hexosamini-dase-B: Studies in Tay-Sachs' and Sandhoff's Disease

1973 • 100 citations

Apparent deficiency of hexosaminidase A in healthy members of a family with Tay-Sachs disease.

1973 • 97 citations

Specificity of Human Liver Hexosaminidases A and B against Glycosphingolipids G_M2and G_A2. Purification of the Enzymes by Affinity Chromatography Employing Specific Elution

1977 • 91 citations

Absence of Hexosaminidase a and B in a Normal Adult

1975 • 67 citations

Absence of -N-acetyl-D-hexosaminidase A activity in a healthy woman.

1973 • 65 citations

A new variant of Type-AB GM2-gangliosidosis

1981 • 63 citations

Ganglioside catabolism in hexosaminidase A-deficient adults

1974 • 53 citations

Adult GM ₂ gangliosidosis in association with Tay‐Sachs disease

1981 • 52 citations

Purification and chemical characterization of human hexosaminidases A and B

1976 • 41 citations

Segregation within a family of two mutant alleles for hexosaminidase A

1976 • 38 citations

The Biochemistry of Sphingolipid Storage Diseases

1977 • 33 citations

Characterization of unusual hexosaminidase A (HEX A) deficient human mutants.

1978 • 32 citations

Characterization of a variant of beta-hexosaminidase: "hexosaminidase Paris".

1977 • 29 citations

Low levels of beta hexosaminidase A in healthy individuals with apparent deficiency of this enzyme.

1976 • 27 citations

Juvenile GM2-Gangliosidose mit ver�nderter Substratspezifit�t der Hexosaminidase A

1974 • 24 citations

Assay of ganglioside activity in human fibroblasts employing the natural activator protein — Diagnosis of variant forms of GM2 gangliosidosis

1980 • 20 citations