Effect of Met-tRNAf deacylase on polypeptide chain initiation in rabbit reticulocyte lysate.

Initiation of Eukaryotic Protein Synthesis: [Met-tRNAf.40S Ribosome] Initiation Complex Catalysed by Purified Initiation Factors in the Absence of mRNA

1973 • 306 citations

Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase

1979 • 263 citations

Regulation of protein synthesis in reticulocyte lysates: phosphorylation of methionyl-tRNAf binding factor by protein kinase activity of translational inhibitor isolated from hemedeficient lysates.

1976 • 221 citations

Regulation of protein synthesis: Activation by double-stranded RNA of a protein kinase that phosphorylates eukaryotic initiation factor 2

1978 • 206 citations

Control of Protein Synthesis in Reticulocyte Lysates by Haemin

1973 • 201 citations

Specificity of the protein kinase activity associated with the hemin-controlled repressor of rabbit reticulocyte.

1976 • 200 citations

Recently discovered systems of enzyme regulation by reversible phosphorylation

1980 • 156 citations

Purification and characterization of protein synthesis initiation factors eIF-1, eIF-4C, eIF-4D, and eIF-5 from rabbit reticulocytes.

1978 • 154 citations

Purification and physical properties of homogeneous initiation factor MP from rabbit reticulocytes

1975 • 151 citations

Control of globin synthesis by hemin: Factors influencing formation of an inhibitor of globin chain initiation in reticulocyte lysates

1972 • 141 citations

Hemin control of globin synthesis: An assay for the inhibitor formed in the absence of hemin and some characteristics of its formation

1971 • 138 citations

Protein Synthesis Initiation in Eukaryotes

1973 • 131 citations

Purification and characterization of initiation factor IF-E2 from rabbit reticulocytes.

1976 • 127 citations

International symposium on protein synthesis Summary of Fogarty Center‐NIH Workshop held in Bethesda, Maryland on 18–20 October, 1976

1977 • 123 citations

Additional evidence that the hemin-controlled translational repressor from rabbit reticulocytes is a protein kinase

1977 • 122 citations

Control of Globin Synthesis in Cell-Free Preparations of Reticulocytes by Formation of a Translational Repressor That is Inactivated by Hemin

1972 • 112 citations

Involvement of hemin, a stimulatory fraction from ribosomes and a protein synthesis inhibitor in the regulation of hemoglobin synthesis

1972 • 97 citations

Characterization of double-stranded-RNA-activated kinase that phosphorylates α subunit of eukaryotic initiation factor 2 (eIF-2α) in reticulocyte lysates

1980 • 93 citations

Cytoplasm from Poliovirus-infected HeLa Cells inhibits Cell-free Haemoglobin Synthesis

1971 • 90 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: Additional initiation factor required for formation of ternary complex (eIF-2·GTP·Met-tRNA _f ) and demonstration of inhibitory effect of heme-regulated protein kinase

1979 • 86 citations

Regulation of protein synthesis in rabbit reticulocyte lysates by the heme-regulated protein kinase: Inhibition of interaction of Met-tRNA _f ^Met binding factor with another initiation factor in formation of Met-tRNA _f ^Met ·40S ribosomal subunit complexes

1978 • 80 citations

Purification and characterization of homogeneous initiation factor M2A from rabbit reticulocytes.

1975 • 76 citations

Mode of action of the hemin-controlled inhibitor of protein synthesis: studies with factors from rabbit reticulocytes.

1978 • 75 citations

Protein synthesis in rabbit reticulocytes: mechanism of protein synthesis inhibition by heme-regulated inhibitor.

1979 • 74 citations

Mode of action of the heme-controlled translational inhibitor: relationship of eukaryotic initiation factor 2-stimulating protein to translation restoring factor.

1981 • 67 citations

Control of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits formation of 80 S initiation complexes from 48 S intermediate initiation complexes

1979 • 59 citations

Control of protein synthesis by hemin. Isolation and characterization of a supernatant factor from rabbit reticulocyte lysate

1976 • 50 citations

Met-tRNA hydrolase from reticulocytes specific for Met-tRNAfMet on 40S ribosomal subunits

1972 • 50 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: Purification and initial characterization of the double stranded RNA activated protein kinase

1980 • 44 citations

Isolation and Characterization of Two Methionine: tRNA Ligases from Wheat Germ

1977 • 40 citations

Regulation of protein synthesis in rabbit reticulocyte lysates: The heme-regulated protein kinase (HRI) and double stranded RNA induced protein kinase (dRI) phosphorylate the same site(s) on initiation factor eIF-2

1979 • 40 citations

Partial reaction of peptide initiation inhibited by the reticulocyte hemin-controlled repressor

1976 • 38 citations

Purification and properties of the double-stranded RNA-activated eukaryotic initiation factor 3 kinase from rabbit reticulocytes.

1980 • 38 citations

Protein synthesis in rabbit reticulocytes: Control of protein synthesis initiation by a Met-tRNAfMet deacylase and peptide chain initiation factors

1973 • 37 citations

Control of globin synthesis by hemin An intermediate form of the translational repressor in rabbit reticulocyte lysates

1974 • 36 citations

Regulation of protein synthesis in reticulocyte lysates: immune serum inhibits heme-regulated protein kinase activity and differentiates heme-regulated protein kinase from double-stranded RNA-induced protein kinase.

1979 • 36 citations

Protein synthesis in rabbit reticulocytes. Purification and characterization of a double-stranded RNA-dependent protein synthesis inhibitor from reticulocyte lysates.

1981 • 35 citations

Protein synthesis in rabbit reticulocytes: characteristics of a postribosomal supernatant factor that reverses inhibition of protein synthesis in heme-deficient lysates and inhibition of ternary complex (Met-tRNAfMet.eIF-2.GTP) formation by heme-regulated inhibitor.

1979 • 35 citations

Identification of a Mr = 39,000 phosphoprotein in highly purified preparations of rabbit reticulocyte eIF-2 that is distinct from the Mr = 35,000 subunit phosphorylated by the hemin-controlled translational repressor.

1980 • 25 citations

Isolation of two initiation factors that can partially reverse the inhibition of protein synthesis due to hemin deficiency or the hemin-controlled translational repressor in rabbit reticulocyte lysates

1977 • 18 citations

Characterization of a rabbit reticulocyte supernatant factor that reverses the translational inhibition of hemin deficiency

1981 • 13 citations

Regulation of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits the rate of formation of 40S.Met-tRNAf complexes directly

1979 • 13 citations

Protein synthesis in rabbit reticulocytes. Preparation of homogeneous Met-tRNAf deacylase and studies of its role in protein synthesis.

1980 • 8 citations

Rabbit reticulocyte double‐stranded RNA‐activated protein kinase and the hemin‐controlled translational repressor phosphorylate the same M_r 1500 peptide of eukaryotic initiation factor 2α

1981 • 7 citations

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