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Regulation of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits the rate of formation of 40S.Met-tRNAf complexes directly

Data up to Jan 2025

Published1979
Citations13
References31

Total Citations Per Year

Abstract

References (31)

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes.

1978 • 436 citations

Initiation of mammalian protein synthesis

1977 • 337 citations

Initiation of Eukaryotic Protein Synthesis: [Met-tRNAf.40S Ribosome] Initiation Complex Catalysed by Purified Initiation Factors in the Absence of mRNA

1973 • 306 citations

Initiation of protein synthesis: Evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit

1973 • 296 citations

Regulation of protein synthesis in reticulocyte lysates: phosphorylation of methionyl-tRNAf binding factor by protein kinase activity of translational inhibitor isolated from hemedeficient lysates.

1976 • 221 citations

Control of Protein Synthesis in Reticulocyte Lysates by Haemin

1973 • 201 citations

Specificity of the protein kinase activity associated with the hemin-controlled repressor of rabbit reticulocyte.

1976 • 200 citations

Hemin control of globin synthesis: An assay for the inhibitor formed in the absence of hemin and some characteristics of its formation

1971 • 138 citations

Protein Synthesis Initiation in Eukaryotes

1973 • 131 citations

Purification and characterization of initiation factor IF-E2 from rabbit reticulocytes.

1976 • 127 citations

Additional evidence that the hemin-controlled translational repressor from rabbit reticulocytes is a protein kinase

1977 • 122 citations

Eukaryotic initiation complex formation. Evidence for two distinct pathways

1975 • 122 citations

Control of Globin Synthesis in Cell-Free Preparations of Reticulocytes by Formation of a Translational Repressor That is Inactivated by Hemin

1972 • 112 citations

Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation.

1978 • 107 citations

Met-tRNA f Met Binding to 40S Ribosomal Subunits: A Site for the Regulation of Initiation of Protein Synthesis by Hemin

1974 • 103 citations

Involvement of hemin, a stimulatory fraction from ribosomes and a protein synthesis inhibitor in the regulation of hemoglobin synthesis

1972 • 97 citations

Preparation and analysis of l-[35S]methionine labeled transfer ribonucleic acids from rabbit liver

1972 • 88 citations

Regulation of protein synthesis in rabbit reticulocyte lysates by the heme-regulated protein kinase: Inhibition of interaction of Met-tRNA f Met binding factor with another initiation factor in formation of Met-tRNA f Met ·40S ribosomal subunit complexes

1978 • 80 citations

Partial purification of a translational repressor mediating hemin control of globin synthesis and implication of results on the site of inhibition

1973 • 79 citations

Mode of action of the hemin-controlled inhibitor of protein synthesis: studies with factors from rabbit reticulocytes.

1978 • 75 citations

Control of protein synthesis in reticulocyte lysates: The effect of nucleotide triphosphates on formation of the translational repressor

1975 • 73 citations

Two Eukaryotic Initiation Factors (IF-I and IF-II) of Protein Synthesis that Are Required to Form an Initiation Complex with Rabbit Reticulocyte Ribosomes

1974 • 67 citations

Control of protein synthesis by hemin. Evidence that the hemin-controlled translational repressor inhibits formation of 80 S initiation complexes from 48 S intermediate initiation complexes

1979 • 59 citations

Control of protein synthesis by hemin. Isolation and characterization of a supernatant factor from rabbit reticulocyte lysate

1976 • 50 citations

Identification of a 48 S preinitiation complex in reticulocyte lysate.

1978 • 49 citations

The Role of Complexes between the 40-S Ribosomal Subunit and Met-tRNAMetf in the Initiation of Protein Synthesis in the Wheat-Germ System

1977 • 42 citations

Partial reaction of peptide initiation inhibited by the reticulocyte hemin-controlled repressor

1976 • 38 citations

THE CONTROL OF GLOBIN SYNTHESIS IN RABBIT RETICULOCYTES *

1974 • 38 citations

Heterogeneity of the small ribosomal subunit and mechanism of chain initiation in eukaryotes

1972 • 36 citations

ATP requirement for binding of 125I-labeled globin mRNA to Artemia salina ribosomes

1976 • 25 citations

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Regulation of protein synthesis by hemin. Evidence that the hemin-controlled… (1979) – Journal of Biological Chemistry | Metascience Observatory Explorer