Differentiation-dependent expression of catecholamine-stimulated adenylate cyclase. Roles of the beta-receptor and G/F protein in differentiating 3T3-L1 adipocytes.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

1977 • 726 citations

Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells.

1978 • 678 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

Relationship between the beta-adrenergic receptor and adenylate cyclase.

1977 • 497 citations

Purification of the regulatory component of adenylate cyclase.

1980 • 497 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.

1978 • 372 citations

Catecholamine-specific desensitization of adenylate cyclase. Evidence for a multistep process.

1980 • 342 citations

An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.

1976 • 318 citations

Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides.

1976 • 314 citations

Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.

1978 • 281 citations

Selection of a Variant Lymphoma Cell Deficient in Adenylate Cyclase

1975 • 276 citations

Coupling of catecholamine receptor from one cell with adenylate cyclase from another cell by cell fusion.

1976 • 240 citations

Acquisition of increased hormone sensitivity during in vitro adipocyte development.

1977 • 221 citations

Characterization and comparison of membrane-associated and cytosolic cAMP-dependent protein kinases. Physicochemical and immunological studies on bovine cerebral cortex protein kinases.

1979 • 188 citations

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.

1977 • 173 citations

GTP stimulates and inhibits adenylate cyclase in fat cell membranes through distinct regulatory processes.

1977 • 120 citations

Adenylate cyclase assembled in vitro: cholera toxin substrates determine different patterns of regulation by isoproterenol and guanosine 5'-triphosphate.

1979 • 114 citations

Beta adrenergic receptors and adenylate cyclase: products of separate genes?

1976 • 98 citations

Determination of the turn-off reaction for the hormone-activated adenylate cyclase.

1979 • 98 citations

The requirement of guanine nucleotides for glucagon stimulation of adenylate cyclase in rat liver plasma membranes.

1977 • 93 citations

The regulatory component of adenylate cyclase from uncoupled S49 lymphoma cells differs in charge from the wild type protein.

1980 • 92 citations

Transient and steady state kinetics of the interaction of guanyl nucleotides with the adenylyl cyclase system from rat liver plasma membranes. Interpretation in terms of a simple two-state model.

1980 • 92 citations

Transfer of glucagon receptor from liver membranes to a foreign adenylate cyclase by a membrane fusion procedure

1979 • 89 citations

Evidence for specific binding sites for guanine nucleotides in adipocyte and hepatocyte plasma membranes. A difference in fate of GTP and guanosine 5'-(beta, gamma-imino) triphosphate.

1975 • 79 citations

Divalent cation-induced desensitization of glucagon-stimulable adenylyl cyclase in rat liver plasma membrane. GTP-dependent stimulation by glucagon.

1980 • 64 citations

[4] Separation of cyclic nucleotides by thin-layer chromatography on polyethyleneimine cellulose

1974 • 49 citations

Peptide mapping of adenylate cyclase regulatory proteins that are cholera toxin substrates.

1980 • 47 citations

Stimulatory and inhibitory effects of ATP-regenerating systems on liver adenylate cyclase.

1980 • 35 citations

Prostaglandins increase GTP hydrolysis by membranes from human mononuclear cells.

1980 • 27 citations

Hybridization of adenylate cyclase components by membrane fusion and the effect of selective digestion by trypsin.

1980 • 24 citations