Synthesis of l-carnitine by microorganisms and isolated enzymes
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Abstract
References (106)
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1970 • 133 citations
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1905 • 131 citations
Effects of Testosterone on the Distribution of Carnitine, Acetylcarnitine, and Carnitine Acetyltransferase in Tissues of the Reproductive System of the Male Rat
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1991 • 81 citations
Comparison of the carnitine acyltransferase activities from rat liver peroxisomes and microsomes
1976 • 78 citations
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1961 • 77 citations
Mikrobielle asymmetrische Katalyse — enantioselektive Reduktion von Ketonen
1984 • 75 citations
Carnitine precursors in the rat
1962 • 75 citations
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1988 • 73 citations
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1965 • 71 citations
On the steric course of baker's yeast mediated reduction of alkyl 4-azido- and 4-bromo-3-oxobutyrate. Synthesis of ()- and ()-carnitin
1985 • 68 citations
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Electrochemical Decarboxylation of Hydroxyproline: A Simple Three-Step Conversion of (2S,4R)-4-Hydroxyproline to (R)-γ-Amino-β-hydroxybutanoic Acid (GABOB)
1986 • 61 citations
Purification and properties of γ-butyrobetaine hydroxylase from Pseudomonas species AK 1
1977 • 60 citations
Localization of carnitine acetyltransferase in peroxisomes and in mitochondria of n‐alkane‐grown candida tropicalis
1978 • 54 citations
Enzymic hydrolysis of alkyl 3,4-epoxybutyrates. A new route to (R)-(-)-carnitine chloride
1988 • 54 citations
Verwertung von Trimethylammoniumverbindungen durch Acinetobacter calcoaceticus
1977 • 53 citations
Significance of renal gamma-butyrobetaine hydroxylase for carnitine biosynthesis in man.
1980 • 52 citations
Mechanism of .alpha.-ketoglutarate oxidation in coupled enzymic oxygenations
1969 • 52 citations
Synthesis of S- and R-4-Amino-3-hydroxybutyric Acid (GABOB) and S- and R-Carnitine from Arabinose or Ascorbic Acid.
1983 • 51 citations
γ-Butyrobetaine hydroxylase from Pseudomonas sp AK 1
1970 • 50 citations
Purification and properties of carnitine dehydratase from Escherichia coli — a new enzyme of carnitine metabolization
1989 • 47 citations
L‐Carnitine. Novel Synthesis and Determination of the Optical Purity
1987 • 47 citations
Stimulation of the anaerobic growth ofSalmonella typhimurium by reduction ofl-carnitine, carnitine derivatives and structure-related trimethylammonium compounds
1982 • 47 citations
Purification and Properties of Carnitine Acetyltransferase from Rat Liver1
1983 • 46 citations
Peroxisomal and Mitochondrial Carnitine Acetyltransferases in Alkane‐Grown Yeast Candida tropicalis
1982 • 45 citations
Reaction of B-alkyl-9-borabicyclo[3.3.1]nonanes with carbon monoxide in the presence of lithium tri-t-butoxyaluminohydride. The conversion of functionally substituted olefins into aldehydes via hydroboration
1969 • 44 citations
.gamma.-Butyrobetaine hydroxylase: stereochemical course of the hydroxylation reaction
1985 • 43 citations
The Formation and Degradation of Carnitine in Pseudomonas*
1967 • 42 citations
A new, short and efficient synthesis of both enantiomers of carnitine
1990 • 42 citations
Preparative Asymmetric Reduction of 3‐Ketobutyrate and ‐valerate by Suspended Cells of Thermophilic Bacteria (Thermoanaerobium brockii) in Ordinary Laboratory Equipment
1985 • 42 citations
Substrate modification as a means of enhancing the enantioselectivity of microbial reductions of .beta.-keto esters. A (R)- or (S)-1,3,5-trihydroxypentane synthon
1987 • 41 citations
Über Liebig's Fleischextrakt
1905 • 39 citations
Purification and properties of calf liver γ-butyrobetaine hydroxylase
1981 • 38 citations
Isolation and characterization of carnitine acetyltransferase from S. cerevisiae
1991 • 38 citations
Enzymatic Synthesis of l -Carnitine by Reduction of an Achiral Precursor: the Problem of Reduced Nicotinamide Adenine Dinucleotide Recycling
1980 • 36 citations
An inducible carnitine dehydrogenase from Pseudomonas aeruginosa
1967 • 36 citations
Reinigung und Eigenschaften der Carnitindehydrogenase aus Pseudomonas aeruginosa
1968 • 36 citations
Carnitine deficiency
1985 • 35 citations
Cholinesterase‐catalyzed resolution of <scp>D</scp>,<scp>L</scp>‐carnitine
1984 • 32 citations
Biochemical profile of propionyl-L-carnitine
1991 • 32 citations
Splitting of the C-N bond in carnitine by an enzyme (trimethylamine forming) from membranes ofAcinetobacter calcoaceticus
1982 • 32 citations
Stoffwechsel des l-Carnitins bei Enterobakterien
1980 • 32 citations
Formation of γ-butyrobetaine and trimethylamine from quaternary ammonium compounds structure-related to l-carnitine and choline byProteus vulgaris
1982 • 32 citations
Regulation of L‐carnitine metabolism in Escherichia coli
1987 • 31 citations
Stereoselective reduction of non-cyclic carbonyl compounds by some eumycetes
1986 • 31 citations
Uncoupling in the γ-butyrobetaine hydroxylase reaction by D=- and L=-carnitine
1982 • 31 citations
Carnitine biosynthesis in Neurospora crassa: enzymatic conversion of lysine to epsilon-N-trimethyllysine
1976 • 31 citations
Stoffwechsel des l‐Carnitins bei Enterobakterien
1980 • 31 citations
Die Darstellung von L-Carnitin und seiner Isomeren
1960 • 29 citations
Beziehungen zwischen Carnitinstoffwechsel und Fetts�ureassimilation bei Pseudomonas putida
1978 • 28 citations
Enzymic synthesis of L-acetylcarnitine and citric acid using acetyl coenzyme A recycling
1986 • 28 citations
Purification of S-adenosylmethionine: epsilon-N-L-lysine methyltransferase. The first enzyme in carnitine biosynthesis.
1977 • 27 citations
Amperometric bienzyme electrode for l-carnitine
1988 • 27 citations
Purification of clofibrate-induced carnitine acetyltransferase from rat liver mitochondria
1980 • 27 citations
Rat liver .gamma.-butyrobetaine hydroxylase catalyzed reaction: influence of potassium, substrates, and substrate analogs on hydroxylation and decarboxylation
1988 • 27 citations
Multiple forms of γ-butyrobetaine hydroxylase (EC 1.14.11.1)
1984 • 26 citations
Characterization of peroxisomal and mitochondrial carnitine acetyltransferases purified from alkane‐grown Candida tropicalis
1984 • 26 citations
A new chemical method for synthesizing and recycling acyl coenzyme A thioesters
1991 • 26 citations
γ-Butyrobetaine hydroxylase: A unique protective effect of catalase
1982 • 22 citations
Assimilation of ?-butyrobetaine, and d-and l-carnitine by resting cell suspensions of Acinetobacter calcoaceticus and Pseudomonas putida
1982 • 22 citations
A biosynthetic role for carnitine in the yeast Torulopsis bovina.
1983 • 22 citations
Carnitine acetyltransferase activity in oleaginous yeasts
1985 • 22 citations
Synthesis of l(-)-carnitine by hydration of crotonobetaine by enterobacteria
1988 • 21 citations
Racematspaltung von DL-Carnitin
1972 • 21 citations
Quantitative aspects of γ-butyrobetaine and d- and l-carnitine utilization by growing cell cultures ofAcinetobacter calcoaceticusandPseudomonas putida
1983 • 21 citations
Transport of gamma-butyrobetaine in an Agrobacterium species isolated from soil
1986 • 20 citations
Water Pollution Biology
1990 • 19 citations
Purification and properties of carnitine dehydrogenase from Pseudomonas putida
1988 • 18 citations
Bioconversion of a L-carnitin precursor in a one- or two-phase system
1991 • 16 citations
Carnitine Deficiency Revisited
1987 • 15 citations
Purification of carnitine acetyltransferase from Candida tropicalis
1982 • 11 citations
Reduktion von L-Carnitin zu γ-Butyrobetain durchEscherichia coli
1979 • 11 citations
Quantitative Bestimmung von l-Carnitin mit Hilfe von Carnitindehydrogenase aus Pseudomonas putida
1985 • 11 citations
gamma-Butyrobetaine hydroxylase and the protective role of glutathione peroxidase.
1987 • 10 citations
D,L-Carnitine resolution byFusarium oxysporum
1986 • 10 citations
Reduktion von L‐Carnitin zu γ‐Butyrobetain durch Escherichia coli
1979 • 9 citations
Influence of carnitine on the growth and productivity of murine hybridoma cells
1991 • 8 citations
Kinetische Untersuchungen zum Reaktionsmechanismus der Carnitindehydrogenase aus Pseudomonas aeruginosa
2005 • 7 citations
Detection of ligand-protein binding by direct electrophoresis of the complex
1988 • 6 citations
Characterization of a soluble carnitine acetyltransferase from Candida tropicalis
1987 • 6 citations
[Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa].
1969 • 5 citations
Evidence for a role of a vicinal dithiol in the transport of γ-butyrobetaine inAgrobacterium sp.
1988 • 5 citations
Purification and properties of the gamma-butyrobetaine-binding protein from an Agrobacterium sp
1988 • 3 citations
S‐(p‐Azidophenacyl)thiocarnitine specifically binds to the γ‐butyrobetaine‐binding protein of Agrobacterium sp. and can be used as a photoaffinity label
1988 • 3 citations
Metabolism of Trimethylammonium Compounds by Acinetobacter
1991 • 1 citations
Deleted Work
1955 • 0 citations