Blood Coagulation in Hemophilia A and Hemophilia C

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The coagulation cascade: initiation, maintenance, and regulation

1991 • 1,810 citations

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

1964 • 1,099 citations

Waterfall Sequence for Intrinsic Blood Clotting

1964 • 1,088 citations

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

1989 • 1,059 citations

A simple method for the preparation of homogeneous phospholipid vesicles

1977 • 861 citations

Surface-dependent reactions of the vitamin K-dependent enzyme complexes

1990 • 853 citations

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.

1977 • 791 citations

Factor XI Activation in a Revised Model of Blood Coagulation

1991 • 774 citations

Hemostasis and Thrombosis: Basic Principles and Clinical Practice

1994 • 723 citations

Purification and Characterization of TAFI, a Thrombin-activable Fibrinolysis Inhibitor

1995 • 684 citations

The contribution of bovine Factor V and Factor Va to the activity of prothrombinase.

1979 • 592 citations

Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation

1993 • 505 citations

The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action

1988 • 482 citations

The Tissue Factor Pathway: How It Has Become a “Prima Ballerina”

1995 • 419 citations

Activation of human blood coagulation factor XI independent of factor XII.

1991 • 413 citations

Blood clotting in minimally altered whole blood

1996 • 400 citations

Regulation of coagulation by a multivalent Kunitz-type inhibitor

1990 • 366 citations

D-PHE-PRO-ARGCH2Cl-A selective affinity label for thrombin

1979 • 327 citations

Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis

1995 • 295 citations

TISSUE FACTOR PATHWAY INHIBITOR AND THE REVISED THEORY OF COAGULATION

1995 • 276 citations

Thrombin, Thrombomodulin and TAFI in the Molecular Link Between Coagulation and Fibrinolysis

1997 • 257 citations

A model for the tissue factor pathway to thrombin. I. An empirical study.

1994 • 242 citations

Characterization of the Molecular Defect in Factor VR506A

1995 • 230 citations

Coagulation-dependent inhibition of fibrinolysis: role of carboxypeptidase-U and the premature lysis of clots from hemophilic plasma

1996 • 211 citations

Regulation of Tissue Factor Initiated Thrombin Generation by the Stoichiometric Inhibitors Tissue Factor Pathway Inhibitor, Antithrombin-III, and Heparin Cofactor-II

1997 • 199 citations

A model for the tissue factor pathway to thrombin. II. A mathematical simulation.

1994 • 183 citations

Factor XI Deficiency

1993 • 173 citations

Hageman factor fragment inhibitor in corn seeds: Purification and characterization

1980 • 168 citations

Surface-dependent hemostasis.

1992 • 167 citations

Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation

1995 • 162 citations

Human platelets contain and secrete osteonectin, a major protein of mineralized bone.

1986 • 148 citations

Inhibition of factor VIIa/tissue factor-induced blood coagulation: with particular emphasis upon a factor Xa-dependent inhibitory mechanism

1989 • 141 citations

Epsilon‐Aminocaproic Acid Therapy for Dental Extractions in Haemophilia and Christmas Disease: A Double Blind Controlled Trial

1971 • 140 citations

Complex-dependent inhibition of factor VIIa by antithrombin III and heparin.

1993 • 137 citations

Evaluation of the Initiation Phase of Blood Coagulation Using Ultrasensitive Assays for Serine Proteases

1997 • 134 citations

Inhibitory Mechanism of the Protein C Pathway on Tissue Factor-induced Thrombin Generation

1997 • 122 citations

Factor‐Xa Inactivation by Antithrombin III

1973 • 120 citations

In situ-generated thrombin is the only enzyme that effectively activates factor VIII and factor V in thromboplastin-activated plasma

1989 • 105 citations

Role of antithrombin III as a regulator of in vivo coagulation.

1991 • 79 citations

Physiological concentrations of tissue factor pathway inhibitor do not inhibit prothrombinase

1996 • 77 citations

Tissue factor-dependent activation of tritium-labeled factor IX and factor X in human plasma

1984 • 70 citations

Production and Therapeutic Use of a Factor XI Concentrate from Plasma

1992 • 70 citations

The haemostatic plug in haemophilia A: a morphological study of haemostatic plug formation in bleeding time skin wounds of patients with severe haemophilia A

1984 • 58 citations

Activation of factor XI in plasma is dependent on factor XII [see comments]

1993 • 57 citations

Proteolytic events that regulate factor V activity in whole plasma from normal and activated protein C (APC)-resistant individuals during clotting: an insight into the APC-resistance assay

1996 • 56 citations

Activation of factor XI in plasma is dependent on factor XII [see comments]

1993 • 49 citations

Factor XI: A Review of Its Biochemistry and Deficiency

1991 • 48 citations

Tissue Extract and the Contact Reaction in Blood Coagulation

1961 • 45 citations

Surface Independent Factor XI Activation by Thrombin in the Presence of High Molecular Weight Kininogen

1994 • 43 citations

Human platelet osteonectin: release, surface expression, and partial characterization

1990 • 39 citations

A conserved epitope on several human vitamin K-dependent proteins. Location of the antigenic site and influence of metal ions on antibody binding.

1988 • 38 citations

Aminonaphthalenesulfonamides, a new class of modifiable fluorescent detecting groups and their use in substrates for serine protease enzymes

1992 • 36 citations

Monoclonal antibodies to human coagulation factor V and factor Va

1983 • 34 citations

The transformation of hemostatic platelet plugs in normal and Factor IX deficient dogs.

1968 • 29 citations

Platelet-Mediated Trigger Mechanisms in the Contact Phase of Blood Coagulation

1987 • 28 citations

A 5-Nucleotide Insertion in the Antithrombin Gene Causing a Quantitative Antithrombin Deficiency

1997 • 19 citations

Factor XI: a renaissance.

1992 • 15 citations

Deleted Work

1955 • 0 citations