A Role for The Arachidonic Acid Cascade In Fast Synaptic Modulation: Ion Channels and Transmitter Uptake Systems As Target Proteins

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain

1970 • 854 citations

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1987 • 640 citations

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1988 • 600 citations

Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysis.

1980 • 513 citations

G-protein βγ-subunits activate the cardiac muscarinic K+-channel via phospholipase A2

1989 • 438 citations

Direct regulation of ion channels by fatty acids

1991 • 407 citations

Mechanisms generating the time course of dual component excitatory synaptic currents recorded in hippocampal slices

1990 • 396 citations

Arachidonic Acid and Other Fatty Acids Directly Activate Potassium Channels in Smooth Muscle Cells

1989 • 353 citations

Potassium Channels in Cardiac Cells Activated by Arachidonic Acid and Phospholipids

1989 • 329 citations

Arachidonic acid metabolites as intracellular modulators of the G protein-gated cardiac K+ channel

1989 • 299 citations

Reductions of Γ‐Aminobutyric Acid and Glutamate Uptake and (Na⁺+ K⁺)‐ATPase Activity in Brain Slices and Synaptosomes by Arachidonic Acid

1983 • 194 citations

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

1989 • 188 citations

Regulation of synaptic transmission in the central nervous system: Long-term potentiation

1989 • 186 citations

N‐Methyl‐d‐Aspartate‐Sensitive Glutamate Receptors Induce Calcium‐Mediated Arachidonic Acid Release in Primary Cultures of Cerebellar Granule Cells

1990 • 171 citations

Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels

1987 • 170 citations

Arachidonic acid metabolites as mediators of somatostatin-induced increase of neuronal M-current

1990 • 170 citations

LIPID DOMAINS IN MEMBRANES*

1982 • 155 citations

Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: An in vivo study in the dentate gyrus of the rat

1989 • 153 citations

Direct modulation of Aplysia S-K+ channels by a 12-lipoxygenase metabolite of arachidonic acid

1989 • 135 citations

Astrocytes as eicosanoid‐producing cells

1988 • 122 citations

Arachidonic acid modulates hippocampal calcium current via protein kinase C and oxygen radicals

1990 • 122 citations

Reversed-phase high-pressure liquid chromatography of arachidonic acid metabolites formed by cyclooxygenase and lipoxygenases

1985 • 118 citations

Arachidonic acid epoxides. Demonstration through [18O]oxygen studies of an intramolecular transfer of the terminal hydroxyl group of (12S)-hydroperoxyeicosa-5,8,10,14-tetraenoic acid to form hydroxyepoxides.

1984 • 117 citations

Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons.

1989 • 87 citations

Effect of Bicuculline‐Induced Status Epilepticus on Prostaglandins and Hydroxyeicosatetraenoic Acids in Rat Brain Subcellular Fractions

1987 • 80 citations

Products of heme-catalyzed transformation of the arachidonate derivative 12-HPETE open S-type K+ channels in Aplysia

1989 • 78 citations

Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds

1985 • 40 citations

Formation of 12-lipoxygenase metabolites in rat cerebral cortical slices: stimulation by calcium ionophore, glutamate and N-methyl-D-aspartate

1990 • 13 citations